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protein biomarkers

Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review

Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review

... far, protein biomarkers are still recognized as a golden standard for PC diagnosis ...PC protein biomark- ers, aiming at better performance of cancer diagnosis such as easy operation, portability, ...

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Prognostic and Predictive Protein Biomarkers in Laryngeal Squamous Cell Carcinoma—A Systematic Review

Prognostic and Predictive Protein Biomarkers in Laryngeal Squamous Cell Carcinoma—A Systematic Review

... new biomarkers in HNSCC [15], using various proteomic techniques. Protein separation techniques, such as 2-dimensional (2D) dif- ferential in-gel electrophoresis, have allowed large numbers of proteins to ...

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Protein biomarkers in cystic fibrosis research: where next?

Protein biomarkers in cystic fibrosis research: where next?

... of biomarkers and their clinical ...date biomarkers [57]. The validation of a panel of CF­ specific protein biomarkers could precipitate the produc­ tion of novel biomarker arrays or tests for ...

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Integrating multiple ‘omics’ analyses identifies serological protein biomarkers for preeclampsia

Integrating multiple ‘omics’ analyses identifies serological protein biomarkers for preeclampsia

... step, protein detection by our two-dimensional gel is limited to proteins whose serological concentrations are >10 ug/mL, clearly influ- encing the composition of the protein biomarkers we ...

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Wound outcome in combat injuries is associated with a unique set of protein biomarkers

Wound outcome in combat injuries is associated with a unique set of protein biomarkers

... selected protein biomarkers with the re- spective discrimination accuracy ...and protein identifica- ...threonine protein kinase 3, receptor type tyrosine pro- tein phosphotase precursor, ...

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Highly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite  particles

Highly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite particles

... Abstract: Magnetic-based biosensors are attractive for on-site detection of biomarkers due to the low magnetic susceptibility of biological samples. Here, we report a highly sensitive magnetic- based biosensing ...

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Advances in blood-based protein biomarkers for Alzheimer's disease

Advances in blood-based protein biomarkers for Alzheimer's disease

... Th e central role of Aβ in AD suggested that it would be a candidate disease biomarker and, according to a recent review, about 26 investigations have been performed to evaluate both Aβ40 and Aβ42 as useful diagnostic ...

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Original Article Plasma protein biomarkers of ALI and ARDS

Original Article Plasma protein biomarkers of ALI and ARDS

... An antibody-based membrane array for mea- suring inflammatory factors (A Custom Raybio Human Inflammation Antibody Array kit) was purchased from Raybiotech (Norcross, Ga., USA), including our request of 507 inflammato- ...

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Journal of Applied Pharmaceutical Science

Journal of Applied Pharmaceutical Science

... biomarkers could serve as intermediate markers of disease in clinical trials, and also be possible drug ...significant protein biomarkers of phenotype and biological function is an expanding area of ...

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Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals

Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals

... a protein biomarker study evaluating 74 different protein biomarkers in plasma samples from case–control patient material consisting of symptomatic individuals represented by CRC patients, adenoma ...

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Redox proteomic identification of carbonylated proteins in autism plasma: insight into oxidative stress and its related biomarkers in autism

Redox proteomic identification of carbonylated proteins in autism plasma: insight into oxidative stress and its related biomarkers in autism

... identify biomarkers for neuropsychiatric disorders including ...in protein concentration, post-translational protein modifications (PTMs) have contributed significantly to the identification of ...

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A Machine Learning Model for Discovery of Protein Isoforms as Biomarkers

A Machine Learning Model for Discovery of Protein Isoforms as Biomarkers

... Wagner et al. discussed various classification approaches using protein profiles from mass spectrometry experiments to discover protein biomarkers [51]. The authors aimed to define peaks with a high ...

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Study of high sensitive c-reactive protein and myoglobin in the saliva of  acute myocardial infarct patients.

Study of high sensitive c-reactive protein and myoglobin in the saliva of acute myocardial infarct patients.

... Three protein biomarkers, cathepsin D, alpha-enolase and beta-2- microglobulin (B2M), and three mRNA biomarkers, myeloid cell nuclear differentiation antigen (MNDA),Guanylate binding protein 2 ...

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Surfactant protein D, Club cell protein 16, Pulmonary and activation-regulated chemokine, C-reactive protein, and Fibrinogen biomarker variation in chronic obstructive lung disease

Surfactant protein D, Club cell protein 16, Pulmonary and activation-regulated chemokine, C-reactive protein, and Fibrinogen biomarker variation in chronic obstructive lung disease

... obtained biomarkers that can identify subtypes of COPD, predict outcomes of COPD, and that can evaluate and facilitate targeting in management of ...of biomarkers for COPD, Sin & Vestbo have formulated ...

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Performance of C reactive protein and procalcitonin to distinguish viral from bacterial and malarial causes of fever in Southeast Asia

Performance of C reactive protein and procalcitonin to distinguish viral from bacterial and malarial causes of fever in Southeast Asia

... the biomarkers to distinguish between infections in the viral aetiological group from those in either of the two bacterial aetiological groups, as well as from the bacteraemia group in ...

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Improved prediction of gestational hypertension by inclusion of placental growth factor and pregnancy associated plasma protein-a in a sample of Ghanaian women

Improved prediction of gestational hypertension by inclusion of placental growth factor and pregnancy associated plasma protein-a in a sample of Ghanaian women

... of biomarkers in prediction models in the clinical setting would be the cost of carrying out biomarker tests, especially in LMIC set- ...the biomarkers in whole blood correlates with that of ...

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2D DIGE analysis of maternal plasma for potential biomarkers of Down Syndrome

2D DIGE analysis of maternal plasma for potential biomarkers of Down Syndrome

... the protein spots (M indicates methionine oxidation) and their position within the protein sequence are shown; also the function of the ...each protein sequence that was ...

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Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature

Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature

... the biomarkers in our BCa- associated diagnostic signature are largely reflected in solid tumor tissues and specific associations with grade and stage and DSS were ...immunohistochemical biomarkers may aid ...

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Loss of integration is associated with reduced resistance to oxidative stress

Loss of integration is associated with reduced resistance to oxidative stress

... and protein carbonyls became significant only in the HF ...both biomarkers of oxidative damage (hydroperoxides and protein carbonyls) were correlated with those in uric acid, but such connections ...

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Development of a Bayesian model to estimate health care outcomes in the severely wounded

Development of a Bayesian model to estimate health care outcomes in the severely wounded

... the biomarkers studied were not additive, they were indeed illustrative of the utility of the modeling process applied in this ...molecular biomarkers in an inter-dependent fashion represents a meaningful ...

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