protein kinase CK2-phosphorylation
Protein Kinase CK2 Phosphorylation of EB2 Regulates Its Function in the Production of Epstein-Barr Virus Infectious Viral Particles
... U2AF protein (48), which by interacting with the heterodimeric ex- port receptor TAP/p15 facilitates the transport of mature mRNPs to and through the nuclear ...cap-binding protein CBP80, which makes ...
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Phosphorylation of PRH/HHEX by Protein Kinase CK2 Regulates Cell Proliferation and Cell Migration in Diverse Cell Types
... PRH expression is up-regulated in the intimal compartment of rat thoracic aortas injured with a balloon embolectomy catheter – a robust model for neointimal hyperplasia [37]. However, PRH mRNA and protein ...
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Eukaryotic Release Factor 1 Phosphorylation by CK2 Protein Kinase Is Dynamic but Has Little Effect on the Efficiency of Translation Termination in Saccharomyces cerevisiae
... contain protein kinases that recognize CK2 protein kinase sites, wild-type eRF1 puri- fied from ...constitutive phosphorylation (eRF1- S421D/S432D) resulted in the appearance of the ...
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Antitumoral activity of allosteric inhibitors of protein kinase CK2
... by CK2 inhibition, we transfected HeLa cells with a CK2α or a GFP- expressing ...of CK2 activity attested by Cdc37 Ser13 phosphorylation which was drastically reduced in U373 cells exposed to ...
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Role of protein kinase CK2 in antitumor drug resistance
... cific CK2 inhibitor CX-4945 (also known as silmitasertib) has been shown to suppress the DNA repair response to anticancer drugs ...of CK2 in DNA damage response and repair pathways has been recently ...
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Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2α’: implications for pathological roles of CK2 in promoting cancer cell survival.
... caspase-3 phosphorylation, we constructed CK2α / α′ chimeras in which three different segments of CK2α′ were swapped into CK2α- HA (Figure 1 C, upper ...for kinase family members (45-300), and the divergent ...
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CK2 Protein Kinase Is Stimulated and Redistributed by Functional Herpes Simplex Virus ICP27 Protein
... elevated CK2 protein levels, aliquots of the extracts used for the in situ gel kinase assay were examined by Western blot analysis to deter- mine the levels of the three CK2 ...of CK2 ...
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Malaria protein kinase CK2 (PfCK2) shows novel mechanisms of regulation
... human protein kinase CK2 in the regulation of cell proliferation and apoptosis, together with the fact that this kinase is up-regulated in cancer, has led to efforts to target protein ...
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Involvement of Plasmodium falciparum protein kinase CK2 in the chromatin assembly pathway
... histone phosphorylation is known to play an important regulatory role in other eukaryotes [49], and in yeast, CK2 phosphorylates histone H4 at serine 1 as part of a DNA damage-signaling pathway ...few ...
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Mitotic Regulation of Protein Kinase CK2
... to CK2, as CK1, another primed kinase, can use both phosphoserine and phosphothreonine as phosphodeterminants ...while CK2 can and in most cases does utilize aspartic acid and glutamic acid as ...
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Phosphorylation of apoptosis repressor with caspase recruitment domain by protein kinase CK2 contributes to chemotherapy resistance by inhibiting doxorubicin induced apoptosis
... of CK2 in some cancer cells is a common downstream response of cells subjected to diverse types of growth stimuli, such as heat shock, UV irradiation and chemicalstress [32, ...example, CK2 translocates to ...
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Hepatitis C Virus NS2 Protein Is Phosphorylated by the Protein Kinase CK2 and Targeted for Degradation to the Proteasome
... (NS2) protein is a hydrophobic transmembrane protein, described to be involved in different functions, such as apoptosis inhibition and gene transcription ...NS2 protein turnover and found that NS2 ...
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Casein Kinase 2-Mediated Phosphorylation of Respiratory Syncytial Virus Phosphoprotein P Is Essential for the Transcription Elongation Activity of the Viral Polymerase; Phosphorylation by Casein Kinase 1 Occurs Mainly at Ser215 and Is without Effect
... P protein can promote transcription initia- tion, but phosphorylation is required for promoter ...Since phosphorylation of P was found to be important for transcription elongation, we sought to ...
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The Human Adenovirus Type 5 E1B 55-Kilodalton Protein Is Phosphorylated by Protein Kinase CK2
... 55-kDa protein (E1B-55K) is a multifunctional phosphoprotein playing several critical roles during adenoviral productive infection, ...potential CK2 consensus phosphorylation ...of CK2 ...
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Coumestrol from the national cancer Institute’s natural product library is a novel inhibitor of protein kinase CK2
... of CK2-specific Akt ...permeable CK2 inhibitor with submicromolar IC50, had inhibition effects on the growth of three cancer cell lines and may represent a promising class of CK2 ...
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Protein kinase CK2 in the ER stress response
... Protein kinase CK2 is a serine/threonine protein kinase composed of two catalytic α- or α’-subunits and two non- catalytic ...that CK2 is implicated in the decision of life and ...
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Phosphorylation of varicella-zoster virus open reading frame (ORF) 62 regulatory product by viral ORF 47-associated protein kinase.
... We showed in this study that in vitro phosphorylation of ORF 62 protein was specific to the protein kinase activity associated with the ORF 47 protein because i phosphorylation could be [r] ...
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Cyclic nucleotide phosphodiesterase 3B is connected to osteopontin and protein kinase CK2 in pancreatic β cells
... phospho- protein 1 (SPP1), is an integrin- and calcium-binding phosphoprotein expressed in multiple cell types and in- volved in a broad spectrum of disease conditions, such as complications associated with ...
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Increased occurrence of protein kinase CK2 in astrocytes in Alzheimer’s disease pathology
... chemoattractant protein-1 (MCP- 1) was determined using the DuoSet MCP-1 enzyme-linked immune sorbent assay (ELISA) (R&D Systems Europe, Abingdon, UK), while for interleukin-6 (IL-6), the Pelipair IL-6 ELISA ...
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Defective expression of p56lck in an infant with severe combined immunodeficiency
... p56lck protein expression. Protein in- stability may account for the decreased expression of the mu- tant (exon 7 deleted) lck ...the kinase domain of ZAP-70 result in diminished or absent levels of ...
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