protein kinases
Nucleoporin Phosphorylation Triggered by the Encephalomyocarditis Virus Leader Protein Is Mediated by Mitogen-Activated Protein Kinases
... other protein kinases, were ...mitogen-activated kinases, p38 and ERK, as possible components in coresponsive cascades ...L protein but not L derivatives harboring knock- ...
11
Insulin receptor substrate 1 is a substrate of the Pim protein kinases
... serine/threonine protein kinases (Pim 1, 2, and 3) contribute to cellular transformation by regulating glucose metabolism, protein synthesis, and mitochondrial oxidative ...Pim protein ...
14
Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses
... form. This may be because a kinase dead form of Chk1 was used and it has been reported that Chk1 kinase activity is required to see the mobility change (Walworth and Bernards, 1996). These results show that the Rad3 ...
11
Dissection of Signal Transduction Networks Using Light-activated Protein Kinases.
... mitogen-activated protein kinase (MAPK) ...three protein kinases in a kinase cascade, and MKK6 is one of the dual-specificity kinases that specifically phosphorylates and activates p38s ...
220
Ecto protein kinases and phosphatases: an emerging field for translational medicine
... extracellular protein phosphorylation activity provide unique opportun- ities for translational medicine to design novel drugs and identify new disease ...extracellular protein kinases and ...
6
Identification and Functional Characterization of GmMYB176-Specific Protein Kinases in Soybean
... candidate protein kinases suggests that there could be more than one GmMYB176-specific protein ...candidate protein kinase may phosphorylate GmMYB176 in any one of putative serine residues, ...
102
Role of Trichoderma reesei mitogen-activated protein kinases (MAPKs) in cellulase formation
... Mitogen-activated protein kinases are ubiquitous pro- tein kinases in eukaryotes that play the role of signal transduction and amplification ...
14
Interacting protein kinases involved in the regulation of flagellar length
... that protein phos- phorylation adds an additional layer to the regulation of flagel- lar maintenance because ⬎80 flagellar components have been found to be phosphorylated in Chlamydomonas (Piperno and Luck, 1976; ...
11
Systematic Deletion Analysis of Fission Yeast Protein Kinases
... Eukaryotic protein kinases are key molecules mediating signal transduction that play a pivotal role in the regulation of various biological processes, including cell cycle progression, cellular ...
15
Computational Modeling of Protein Kinases: Molecular Basis for Inhibition and Catalysis
... Protein kinases catalyze protein phosphorylation reactions, ...many kinases is directly linked to cancer development and the protein kinase family is one of the most important targets ...
157
Regulation of cardiac hypertrophy in vivo by the stress activated protein kinases/c Jun NH2 terminal kinases
... Cardiac hypertrophy often presages the development of heart failure. Numerous cytosolic signaling pathways have been implicated in the hypertrophic response in cardiomyocytes in culture, but their roles in the ...
9
A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases
... of protein kinases include several family members, such as protein kinase A (PKA), cyclic GMP- dependent protein kinase (PKG), and protein kinase C (PKC), that have been implicated in ...
10
Identification of SRPK1 and SRPK2 as the Major Cellular Protein Kinases Phosphorylating Hepatitis B Virus Core Protein
... core protein has recently been shown to be a prerequisite for pregenomic RNA encapsidation into viral capsids, but the host cell kinases mediating this essential step of the HBV replication cycle have not ...
14
Protein Kinases Involved in Mating and Osmotic Stress in the Yeast Kluyveromyces lactis
... In addition to the interaction detected between components of the MAPK module and scaffold proteins, two-hybrid studies indicate that some of the protein kinases associate with each other independently of ...
8
The actions of NME1/NDPK-A and NME2/NDPK-B as protein kinases
... about protein phosphorylation by histidine kinases in animals suggests that the main purpose of this form of phosphorylation is similar to that in the Ser/Thr and Tyr kinase systems ...changing ...
24
The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis
... As we have reviewed here, the differential activation (and inhibition) of distinct protein kinases acts to con- trol the formation of a mature myotube from a popula- tion of embryonic precursors or ...
18
Protein Kinases Are Associated with Multiple, Distinct Cytoplasmic Granules in Quiescent Yeast Cells
... the protein kinase under ...“Insoluble Protein Deposit,” which is thought to contain misfolded protein that forms amyloid and other types of aggregate structures (Kaganovich et ...the protein ...
18
Role of protein kinases in signal transduction and their inhibitors
... necrosis. Protein kinases act as the third messenger system and activity of most of its isoforms often depends upon second messengers such as cAMP and ...of protein kinase is a frequent cause of ...
14
Refolding of protein kinases
... Four protein kinases from the serine/threonine and dual specificity classes of protein kinases, with tyrosine kinases being ...The protein kinases selected were ...
283
Highly conserved protein kinases involved in the regulation of carbon and amino acid metabolism
... GCN2-type protein kinases are another ancient family that evolved before the divergence of plants, animals and ...eIF2a kinases that have similar catalytic domains to GCN2, but do not contain a ...
9