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Proteins identified from mass spectrometry data

ANALYSIS OF PROTEINS AND PROTEOMES BY MASS SPECTROMETRY

ANALYSIS OF PROTEINS AND PROTEOMES BY MASS SPECTROMETRY

... biomolecules, mass spectrometry has become a powerful tool in protein analysis and the key technology in the emerging field of ...of mass spectrom- etry is driven both by innovative instrumentation ...

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LESA FAIMS mass spectrometry for the spatial profiling of proteins from tissue

LESA FAIMS mass spectrometry for the spatial profiling of proteins from tissue

... lipids, proteins and a drug compound in mouse brain tissue ...proteomics data. 28 LESA MSI su ffers from low spatial resolution, typically 500 μm to 1 mm, but has the advantages of sensitivity, ...

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1 Mass Spectrometry of Amino Acids and Proteins

1 Mass Spectrometry of Amino Acids and Proteins

... For these reasons, de novo sequencing typically results in a short list of candidate sequences that each account for the data to varying degrees. Why bother performing a de novo sequence determination when ...

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A Tandem Mass Spectrometry Sequence Database Search Method for Identification of O-Fucosylated Proteins by Mass Spectrometry.

A Tandem Mass Spectrometry Sequence Database Search Method for Identification of O-Fucosylated Proteins by Mass Spectrometry.

... TSR-containing proteins exhibit stability and trafficking defects, while other TSR-containing proteins show no discernable defect from loss of glycosylation 9–10 ...vivo. Mass ...

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Analysis of posttranslational modifications of proteins by tandem mass spectrometry

Analysis of posttranslational modifications of proteins by tandem mass spectrometry

... unmodified proteins and the corresponding proteo- lytic peptides are readily calculated from the protein sequences obtained by the initial sequence database ...a mass increment or mass deficit ...

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Oligoglycerol Detergents for Native Mass Spectrometry of Membrane Proteins

Oligoglycerol Detergents for Native Mass Spectrometry of Membrane Proteins

... protein mass spectra could be obtained directly upon protein ...membrane proteins were easily released from OGDs, which enabled the easy native MS analysis of a challenging ...obtained from ...

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Mass spectrometry-enabled structural biology of membrane proteins

Mass spectrometry-enabled structural biology of membrane proteins

... of data obtained by MS into a structural model can be complex, especially for dynamic systems, wherein model building guided by computer simulations is an essential compo- nent of the MS ...MS data with ...

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Mass Spectrometry-Based Proteomics Analysis of Secreted Proteins

Mass Spectrometry-Based Proteomics Analysis of Secreted Proteins

... bias from the analyst, or the materials ...differences from sample to sample during analysis may affect ...reproducibility from sample run to run is necessary in label-free ...and data ...

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Proteomic Approach for Extracting Cytoplasmic Proteins from Streptococcus sanguinis using Mass Spectrometry

Proteomic Approach for Extracting Cytoplasmic Proteins from Streptococcus sanguinis using Mass Spectrometry

... extracted proteins under the precipitating genomic DNA that is so large and abundant that as it precipitates it can trap proteins or even ...of proteins from the heat elicited by the pressing ...

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Data mining in proteomic mass spectrometry

Data mining in proteomic mass spectrometry

... tracted from the original mass ...the mass spec- trum, estimating the average or minimum intensity within the window, and then moving the window across the spectrum to estimate the overall ...

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MSSimulator: Simulation of Mass Spectrometry Data

MSSimulator: Simulation of Mass Spectrometry Data

... are identified and ...E data, for example, ETISEQ. 21 By providing simulated data, we hope to facilitate algorithm development, as the simulator provides an easy means to benchmark the ...E ...

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Denoising Tandem Mass Spectrometry Data

Denoising Tandem Mass Spectrometry Data

... of proteins is to defend our bodies against infection and keep- ing our bodies in good ...Protein Data Bank (PDB), there are records of about 80,000 entries that is made up of proteins with their ...

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Tandem mass spectrometry of non enzymatically glycated peptides and proteins

Tandem mass spectrometry of non enzymatically glycated peptides and proteins

... Jason from IT, Steve, Phil and Dave from chemistry stores, Marcus and Lee from the workshop, Olvi, Shukhbinder, and Samantha from finance office, Rob Jenkins, Ken Westwood and David ...Smith ...

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Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry

Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry

... derived from a single gene, is their similarity regarding the composition of atoms, making their analysis very chal- ...recombinant proteins are strongly associated with this problem, especially recombinant ...

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proBed: extension of the BED format for mapping peptides identified by mass spectrometry to a genome

proBed: extension of the BED format for mapping peptides identified by mass spectrometry to a genome

... produced from the same genome sequence ...results from the same sample; merged results from different replicates; merged results from different samples and so on (discussion on merging proBed ...

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Ion mobility spectrometry-mass spectrometry of intrinsically unfolded proteins: trying to put order into disorder

Ion mobility spectrometry-mass spectrometry of intrinsically unfolded proteins: trying to put order into disorder

... disordered proteins, apo- cytochrome c and apo-bovine osteocalcin, has produced interesting insights into their respective conformational behaviour ...The data show that it is possible to discern different ...

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Weight Loss Determined from Mass Spectrometry Trend Data in a Thermogravimetric/Mass Spectrometer System

Weight Loss Determined from Mass Spectrometry Trend Data in a Thermogravimetric/Mass Spectrometer System

... the mass spectrometer is used for identification ...known from the TGA, but the weights for the individual components are ...trend data from a mass spectrometer can be used to semi- ...

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Psoriasin, one of several new proteins identified in nasal lavage fluid from allergic and non-allergic individuals using 2-dimensional gel electrophoresis and mass spectrometry

Psoriasin, one of several new proteins identified in nasal lavage fluid from allergic and non-allergic individuals using 2-dimensional gel electrophoresis and mass spectrometry

... The role of these newly identified proteins in allergic rhin- itis is not known and they all render further investigation. However, special attention might be drawn to the two dif- ferent forms of psoriasin ...

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Mass spectrometry data mining for cancer detection

Mass spectrometry data mining for cancer detection

... implemented the following simulations. For each N , we perform 1000 simulations SIM 1 , SIM 2 , · · · , SIM 1000 . In each simulation SIM j , we generate N/2 binary vec- tors of size 10 drawn from the Gibbs ...

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Statistical analysis of proteomic mass spectrometry data

Statistical analysis of proteomic mass spectrometry data

... ing data available for this ...spectra from each day of each group in the training set which may not be a representative sample of the population of ...all, from the boundary if those outliers were ...

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