Proton pump
Deprescribing proton pump inhibitors
... Proton pump inhibitors are used for a number of reasons; however, most deprescribing research has been done in relatively healthy patients (primarily adults and younger elderly patients) with mild or ...
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Proton pump inhibitors in acid-related diseases. Christian Jonasson
... With the sharp increase in the usage of PPIs in the Western world the fear of over- utilisation of PPI is increasing and has implications both in relation to health care expenditure and PPI related adverse events. A ...
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A Retrospective Study on Prescribing Patterns and Cost Analysis of Proton Pump Inhibitors
... Proton Pump Inhibiitors (PPIs) remain the superior choicein the evidence-based treatment of gastrointestinal disorders which include peptic ulcer disease (PUD), dyspepsia, gastro esophageal reflux disease ...
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An Arabidopsis thaliana Plasma Membrane Proton Pump Is Essential for Pollen Development
... membrane proton pump (H ⫹ -ATPase) found in plants and fungi is a P-type ATPase with a polypeptide sequence, structure, and in vivo function similar to the mammalian sodium pump (Na ⫹ , K ⫹ ...the ...
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Treatment with clopidogrel and proton pump inhibitors in combination: a review of emerging evidence
... duce the active metabolite that inhibits platelet aggrega- tion [8]. Metabolism of clopidogrel occurs through two distinct pathways: esterase-mediated hydrolysis into an inactive derivative and activation by multiple ...
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Effects of long term proton pump inhibitors use in pediatrics
... Proton pump inhibitors induce a hypochloridric status. There is increasing medical evidence about adverse effects secondary to long term use. Most of the knowledge arises from large studies in adults. ...
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Effect of Proton Pump inhibitors on laryngopharyngeal reflux disease: A Prospective study
... of proton pump inhibitors on Laryngopharyngeal reflux disease – A prospective study” to be conducted in the department of ENT, Sree Mookambika Institute of Medical Sciences, ...
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Antiplatelet agents and proton pump inhibitors – personalizing treatment
... • Clopidogrel has received considerable attention due to several level 1 studies showing a statistically-significant pharmacody- namic interaction of clopidogrel with proton pump inhibitors. Studies point ...
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Micronutrient Consequences of Long Term Proton Pump Inhibitor Therapy
... Proton pump inhibitors (PPIs) are currently the mainstay of treatment for gastro-oesophageal reflux disease, peptic ulcer disease and dyspepsia. In this area, they have enjoyed remarkable success and there ...
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A Review on Proton Pump Inhibitor for The Treatment of Peptic Ulcer
... of proton-pump inhibitors as long-term treatment for managing GERD, medical societies recommend that patients use the minimal effective dosage to achieve the goals of the ...
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Proton Pump Inhibitors and Corticosteroids as Synergistic Risk Factors for Candida Esophagitis
... There are multiple physiologic defense mechanisms that normally inhibit colonization. Such mechanisms include salivation, mechanical clearance of esophageal luminal contents, a mucosal barrier, an intact pH gradient ...
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Proton-Pump Inhibitors and Hypomagnesaemia in Kidney Transplant Recipients
... Received: 30 October 2019; Accepted: 4 December 2019; Published: 6 December 2019 Abstract: Proton-pump inhibitors (PPIs) are commonly used after kidney transplantation and there is rarely an incentive to ...
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DRUG USE EVALUATION OF PROTON PUMP INHIBITORS IN A TERTIARY CARE HOSPITAL
... Proton Pump Inhibitors (PPIs) are one of the most commonly prescribed category of drugs that cause pronounced and long-lasting suppression of gastric acid production by inhibiting the Hydrogen-Potassium ...
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Evidence based support for the use of proton pump inhibitors in cancer therapy
... of proton pump inhibitors (PPI) currently used for the treatment of peptic disease and as gastroprotectors, and including omeprazole, esomeprazole, lansoprazole, pantoprazole and rabepra- zole, in the ...
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Prescribing efficiency of proton pump inhibitors in China: influence and future directions
... Background: Pharmaceutical expenditure is currently rising by 16% per annum in China, greater in recent years. Initiatives to moderate growth include drug pricing regulations, essential medicine lists and encouraging ...
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Proton pump inhibitors: potential cost reductions by applying prescribing guidelines
... Proton pump inhibitors (PPI) are indicated in the treat- ment of acid related dyspepsia and peptic ulcers and are one of the most frequently prescribed classes of drugs in the world ...
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The potential interaction between clopidogrel and proton pump inhibitors: a systematic review
... confirmation of increased adverse outcomes [4-6]. Recently, mechanistic in vitro studies have suggested that proton pump inhibitors (PPIs) may diminish clopi- dogrel’s clinical efficacy via CYP2C19 ...
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Potential adverse effects of long term use of Proton Pump Inhibitors.
... 21. Thomson AB, Sauve MD, Kassam N, Kamitakahara H. Safety of the long-term use of proton pump inhibitors. World J Gastroenterol. 2010 May 21;16(19):2323-30. https://doi.org/10.3748/wjg.v16.i19.2323 22. ...
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Delirium in the geriatric unit: proton-pump inhibitors and other risk factors
... previously reported: greater age, dementia, congestive heart disease, peripheral artery disease, pressure ulcers, urinary incontinence, permanent or prolonged bladder catheteriza- tion, history of delirium episodes, ...
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Proton pump inhibitor-refractory gastroesophageal reflux disease: challenges and solutions
... Abstract: A significant percentage of patients with gastroesophageal reflux disease (GERD) will not respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are numerous and ...
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