Proton-pump inhibitor
FORMULATION AND EVALUATION OF BILAYER TABLETS OF SUSTAINED RELEASE NSAID’s AND IMMEDIATE RELEASE PROTON PUMP INHIBITOR
... a proton pump inhibitor. Esomeprazole is a proton pump inhibitor, suppress the gastric acid secretion by the specific inhibition of the H+/k+ ATPase enzyme at the secretory ...
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Formulation and Optimization of Oro dispersible Tablet of Pentoprazole Sodium as Proton Pump Inhibitor
... a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by forming a covalent bond to two sites of the (H+, K+)-ATPase enzyme system at the secretory surface of the ...
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Proton pump inhibitor-refractory gastroesophageal reflux disease: challenges and solutions
... Abstract: A significant percentage of patients with gastroesophageal reflux disease (GERD) will not respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are numerous and ...
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Micronutrient Consequences of Long Term Proton Pump Inhibitor Therapy
... PPIs have been a remarkable success story. Omeprazole was the first proton-pump inhibitor to be introduced in Europe in 1988. It was quickly shown to be superior to all previously available ...
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Formulation development of enteric coated tablets of a proton pump inhibitor for stability enhancement
... In the present investigation enteric coated formulation of proton pump inhibitor which is a substituted benzimidazole derivative was developed to enhance its stability. The tablets were coated with ...
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Formulation and optimization of oro dispersible tablet of rabeprazole sodium as proton pump inhibitor
... substituted benzimidazole that inhibits gastric acid secretion. The stability of rabeprazole sodium is function of pH; it is rapidly degraded in acid media, and is more stable under alkaline condition (VL. Kulkarni et ...
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Evaluation of costs accrued through inadvertent continuation of hospital-initiated proton pump inhibitor therapy for stress ulcer prophylaxis beyond hospital discharge: a retrospective chart review
... patients. Proton pump inhibitor (PPI)-based stress ulcer prophylaxis (SUP) has been widely prescribed in noncritically ill patients who are at low risk for clinically significant bleeding, which is ...
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Perceptions of patient-centered care among veterans with gastroesophageal reflux disease on proton pump inhibitor therapy
... The aim of this study was to explore perceptions of patient-centered care (PCC) among Veterans with gastroesophageal reflux disease (GERD) on proton pump inhibitor (PPI) therapy using p[r] ...
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The Proton Pump Inhibitor Omeprazole Does Not Promote Clostridioides difficile Colonization in a Murine Model
... IMPORTANCE Antibiotics are the primary risk factor for Clostridioides difficile infec- tions (CDIs), but other factors may also increase a person’s risk. In epidemiological studies, proton pump ...
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Chronic use of proton pump inhibitor: A Narrative Review
... Because gastric acidity plays the role of protective barrier against infections of the upper gastrointestinal tract, hypochlorite has been associated with increased intestinal infections and respiratory infections caused ...
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Proton pump inhibitor: a risk factor for spontaneous bacterial peritonitis in Indian cirrhotics decompensated with ascites
... Proton pump inhibitor: a risk factor for spontaneous bacterial peritonitis in Indian cirrhotics decompensated with ascites.. Akash Rajender 1 , Priyanka Choudhary 2 *, Saumya Mathur 2 ,[r] ...
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Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis
... of lung inflammation and fibrosis and how these path- ways are affected by esomeprazole. We conducted GeneChip array of lung tissue homogenates using a bio- analyzer as described above. Intriguingly, cluster analysis of ...
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Proton pump inhibitor responsive chronic cough without acid reflux: a case report
... Gastroesophageal reflux disease (GERD)-associated cough is a well-known type of chronic, non-productive cough [1]. Asthma, postnasal drip syndrome, and GERD are the three most frequently identified causes of cough in ...
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Proton pump inhibitor omeprazole attenuates hyperoxia induced lung injury
... Fifteen does 96 pups were used for the assessment of lung function and histology morphometry and immunohistochemistry at day 5 of life Omeprazole was administered prenatally to the doe 2[r] ...
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Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients’ bed
... of proton pumps that avoid intracellular acidifi- cation ...with proton pump inhibitors (PPI) increases tumor cells sensitivity to a variety of anticancer drugs ...
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STABILITY ENHANCEMENT OF PROTON PUMP INHIBITOR IN STOMACH: FORMULATION AND IN VITRO EVALUATION OF STABILIZED PROTON PUMP INHIBITOR
... Formulation of the tablet using pantoprazole rosin complex Pantoprazole sodium tablet was prepared using 10 station automatic tablet compression machine (Rimek Mini Press 1). The excipients were selected based on direct ...
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A Review on Proton Pump Inhibitor for The Treatment of Peptic Ulcer
... Now a day’s peptic ulcer is a common problem associated with g.i.t and is affecting most of the total population due to present life style, intake of unhealthy foods and lack of exercise resulting in imbalance between ...
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CYP2C19 Phenotype and Risk of Proton Pump Inhibitor–Associated Infections
... Gastroesophageal reflux disease is perhaps the most common indication for PPIs in children; however, PPIs are used in a variety of in fl ammatory conditions of the upper intestinal tract. 5 In their activated form, PPIs ...
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Esophageal Strictures during Treatment with a Proton Pump Inhibitor
... Background: The development of esophageal stricture during treatment with high dose chemo- therapeutic agents is well known and documented in the literature. With the introduction of pro- ton pumps inhibitors (PPI), the ...
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A Prospective study on Symptomatic Improvement of Helicobacter pylori Positive patients taking Standard Triple Therapy: A Pilot study
... Although a variety of regimens are available for the eradication of H. pylori, the American College of Gastroenterology still recommends the use of Standard Triple Therapy. The standard triple therapy consisting of ...
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