protoporphyrin IX
Light harvesting in silicon(111) surfaces using covalently attached protoporphyrin IX dyes
... X-ray Photoelectron Spectroscopy: XPS measurements on the samples were performed on a Thermo Fisher ME17 Thetraprobe system with a monochromatic Al X-ray source, set to a 400 µm spot size. The scan count was set to 500 ...
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Carbon dot-protoporphyrin IX conjugates for improved drug delivery and bioimaging
... ethylenediamine, protoporphyrin IX, sodium chloride, resa- zurin sodium salt, (N-(3-Dimethylaminopropyl)-N’-ethylcarbodiimide), N-Hydroxysuccini- mide, formaldehyde, phenalenone, 2-(N-Morpholino) ...
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Zinc Protoporphyrin IX Binds Heme Crystals to Inhibit the Process of Crystallization in Plasmodium falciparum
... zinc protoporphyrin IX, normally present at ...zinc protoporphyrin IX inhibition of heme crystallization similar to the antimalarial ...Zinc protoporphyrin IX neither forms ...
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Enhancement of Cancer-Specific Protoporphyrin IX Fluorescence by Targeting Oncogenic Ras/MEK Pathway
... Among the tumor-specific fluorescent probes used for FGS, 5-Aminolevulinic acid (5-ALA) is the front-runner for tumor-normal border detection with a good safety profile and minimal side effects [4–6]. 5-ALA is a small ...
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Light harvesting in silicon(111) surfaces using covalently attached protoporphyrin IX dyes
... We report the photosensitization of crystalline silicon via energy transfer using covalently attached protoporphyrin IX (PpIX) derivative molecules at different distances via changing the diol linker to the ...
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Klein, Susanne (2005): Einfluss verschiedener Faktoren auf die durch 5-Aminolävulinsäure und ihre Ester induzierte Protoporphyrin IX - Fluoreszenz in Zervixkarzinomzelllinien. Dissertation, LMU München: Medizinische Fakultät
... 4.2.4 Protoporphyrin IX- Fluoreszenz, Dunkeltoxizität und Photodynamische Wirksamkeit in Abhängigkeit von Desferrioxamin bei C33A-Zellen 49 4.3 Einfluss von pH-Wert, Serum, EDTA[r] ...
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Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells
... Results: By employing a drug repurposing approach, we found that protoporphyrin IX (PpIX), a metabolite of ami‑ nolevulinic acid applied in photodynamic therapy of cancer, stabilizes T[r] ...
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A quantitative study of in vivo protoporphyrin IX fluorescence build up during occlusive treatment phases
... Background: Topical photodynamic therapy (PDT) is a non-invasive light based ther- apy used to treat non-melanoma skin cancer (NMSC) and dysplasia. During PDT, the light sensitive molecule protoporphyrin IX ...
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In-vivo kinetics of inhaled 5-Aminolevulinic acid-Induced Protoporphyrin IX fluorescence in bronchial tissue
... The detection of premalignant and early-malignant endo- bronchial alterations is growing increasingly important in the diagnosis of lung cancer, since an acceptable progno- sis is strictly confined to the early stage of ...
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Apoptosis of THP-1 macrophages induced by protoporphyrin IX-mediated sonodynamic therapy
... Protoporphyrin IX, 3-[4,5-dimethylthiazol-2-yl]-2,5- diphenyltetrazolium bromide (MTT), and propidium iodide were purchased from Sigma-Aldrich (St Louis, MO, ...
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Modelling topical photodynamic therapy treatment including the continuous production of Protoporphyrin IX
... Most existing theoretical models of photodynamic therapy (PDT) assume a uniform initial distribution of the photosensitive molecule, Protoporphyrin IX (PpIX). This is an adequate assumption when the prodrug ...
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Killing malignant melanoma cells with protoporphyrin IX-loaded polymersome-mediated photodynamic therapy and cold atmospheric plasma
... Abstract: Traditional cancer treatments contain several limitations such as incomplete ablation and multidrug resistance. It is known that photodynamic therapy (PDT) is an effective treatment for several tumor types ...
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Increase of miR-199a-5p by protoporphyrin IX, a photocatalyzer, directly inhibits E2F3, sensitizing mesenchymal tumor cells to anti-cancer agents
... Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths. Protoporphyrin IX (PPIX) has been used for photodynamic therapy. Mesenchymal cancer cells adapt to tumor microenvironments for ...
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Mg-Protoporphyrin IX and Heme Control HEMA, the Gene Encoding the First Specific Step of Tetrapyrrole Biosynthesis, in Chlamydomonas reinhardtii
... HEMA encodes glutamyl-tRNA reductase (GluTR), which catalyzes the first step specific for tetrapyrrole biosynthesis in plants, archaea, and most eubacteria. In higher plants, GluTR is feedback inhibited by heme and ...
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Her2 oncogene transformation enhances 5-aminolevulinic acid- mediated protoporphyrin IX production and photodynamic therapy response
... Enhanced protoporphyrin IX (PpIX) production in tumors derived from the administration of 5-aminolevulinic acid (ALA) enables the use of ALA as a prodrug for photodynamic therapy (PDT) and ...
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Protoporphyrin IX photobleaching of subcellular distributed sites of leukemic HL60 cells based on ALA PDT in vitro
... induced Protoporphyrin IX photobleaching exhi- bited a complex series of photophysical and photoche- mical reactions and the bleaching kinetics are much more complicated ...the Protoporphyrin ...
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μ Oxo bis[(protoporphyrin IX dimethyl ester)iron(III)]
... The -oxo dimer of iron protoporphyrin IX (FePPIX) is relevant in biology. For example, the black pigment of Porphyromonas gingivalis, a principal agent in adult perio- dontitis, has been identi®ed as the ...
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Factors affecting amninolaevulinic acid-induced generation of protoporphyrin IX
... The aims of this study are: 1 to investigate whether there is production and accumulation of PPIX by vascular endothelial and smooth muscle cells on exposure to ALA and whether this lead[r] ...
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The effect of aminolaevulinic acid-induced, protoporphyrin IX-mediated photodynamic therapy on the cremaster muscle microcirculation in vivo
... A reduction in artenral blood flow during photoactivation, which returned to normal at the end of the recovery period was observed in four of the five preparations.. Venous blood flow wa[r] ...
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Action of protoporphyrin IX (PP IX) in the lifespan of Drosophila melanogaster deficient in endogenous antioxidants, Sod and Cat
... Three groups of 25 males and virgin females 16 h old were placed separately for 24 h in homeopathic vials (10.5 × 2.4 cm) containing 0.7 mg of Drosophila instant medium (Formula 4 - 24 Carolina Biological Supply Co.) ...
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