Proximal tubular cells
Numb Protects Renal Proximal Tubular Cells from Puromycin Aminonucleoside-Induced Apoptosis through Inhibiting Notch Signaling Pathway
... renal proximal tubular cells. Exposure of NRK52E cells to puromycin aminonucleoside (PA) resulted in caspase 3-dependent ...NRK52E cells to PA-induced apoptosis, whereas overexpressing ...
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Overendocytosis of gold nanoparticles increases autophagy and apoptosis in hypoxic human renal proximal tubular cells
... renal proximal tubular cells (HK-2) by Cell Counting Kit-8 assay and lactate dehydrogenase release assay, but we just found the toxic effect in the 5 nm GNP-treated cells at 50 nM dose under ...
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Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells
... for the observed lack of efficacy of 17864-ULS-lysozyme. First, the inhibitor levels reached within the target cells may have been too low. Treatment with a higher dose or repeated doses of 17864-ULS-lysozyme may ...
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Cytokine and Inflammatory-Related Gene Expression of Melamine Cyanurate on Human Renal Proximal Tubular Cells
... and proximal cortical tubule (CRL-2833; ATCC, Manassas, VA) was cultured in Dulbecco’s Modified Eagle’s Medium (DMEM) (ATCC) with 10% fetal bovine serum (GIBCO, New York, NY) and in pre-coated culture flask with ...
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What lies behind serum urate concentration? Insights from genetic and genomic studies
... the proximal tubule in the ...through proximal tubular cells is achieved via uni directional transcellular transport, involving the uptake of urate into the cells from the ...
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Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells
... of proximal tubular cells [25] and related to inhibition of apoptosis and complement activation in reperfusion injury ...mesangial cells and renal fibroblasts ...primary tubular ...
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Local action of phosphate depletion and insulin like growth factor 1 on in vitro production of 1,25 dihydroxyvitamin D by cultured mammalian kidney cells
... in proximal renal tubular ...kidney cells: opossum kidney (OK) cells, LLC-PK 1, and rabbit's proximal tubular ...the cells were incubated for a further 120 ...
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Albumin stimulates interleukin 8 expression in proximal tubular epithelial cells in vitro and in vivo
... through tubular epithelial cell activation ...T cells and macrophages, which appear to play a key role in the subsequent evolution of tubulointerstitial inflamma- tion and fibrosis ...inflammatory ...
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Expression of parathyroid hormone related protein in the rat glomerulus and tubule during recovery from renal ischemia
... in proximal tubular cells after ischemia, changing its location from diffusely cytoplasmic to subapical by 24 h after ...epithelial cells (visceral and parietal), but not to mesangial ...both ...
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Nondestructive Evaluation Of Corrosion Damage In Reinforced Concrete Aged Slab Specimen
... in proximal tubular cells compared with mice with NAFLD alone or BDCM-treated lean mice, thus ruling out the exclusive role of ...T cells (CD1d knockout mice) showed elevated (>4-fold) ...
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Aged garlic extract protects against oxidative stress and renal changes in cisplatin-treated adult male rats
... severe tubular degeneration, tubular necrosis, apoptotic nuclear changes, exfoliation of the proximal tubular epithelial cell lining, shedding of the apical microvilli of the proximal ...
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Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB
... induces antioxidative effects in the kidneys of CKD rats. Consequently, AST-120 relieves suppressed expression of HO-1 and NQO1 and attenuates increase of ROS in the CKD rat kidneys. ROS induces necrosis, apoptosis, ...
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Dexmedetomidine provides renoprotection against ischemia reperfusion injury in mice
... kidney proximal tubular cells (HK2) cells were treated with dexmedetomidine and the time course of phospho-a serine/threonine protein kinase (pAkt) expression in culture homogenised ...
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Angiotensinogen Expression Is Enhanced in the Progression of Glomerular Disease
... renal proximal tubular epithelial cells, Ang II acts synergistically with interleukin-6 to increased AGT expression through acti- vation of nuclear factor-κB and the signal transducer and activator ...
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MicroRNA-34a Is Induced via p53 during Cisplatin Nephrotoxicity and Contributes to Cell Survival
... mouse proximal tubular cells and also in vivo during cisplatin nephrotoxicity in C57BL/6 ...cultured cells, miR-34a was induced within a few ...of proximal tubular ...
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Original Article Ouabain-induced apoptosis and inhibition of viability of tubulointerstitial cells by regulating NKA/pSrc/pERK/ pAkt/pS6k/caspase 3 may contribute to lupus nephritis development
... HK-2 cells apoptosis while it inhibits proliferation in a dose-depen- dent way; moreover, ouabain decreased NKA expression and activated pSrc, pERK, pAkt, pS6K and caspase 3 ...
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Caveolar Endocytosis Is Critical for BK Virus Infection of Human Renal Proximal Tubular Epithelial Cells
... incubation, cells were fixed, immunofluoresced for anti-Cav-1 antibody (red) or anti-clathrin antibody (red), and analyzed by confocal micro- scope using a 63 ⫻ lens ...100 cells randomly selected from ...
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On the influence of extracellular fluid volume expansion on bicarbonate reabsorption in the rat
... possibility exists, therefore, that glomerulo-tubular balance for bicarbonate is altered by the volume expansion and thus that the classic pattern of reabsorption may actually reflect inhibited bicarbonate ...
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Journal of Applied Pharmaceutical Science
... involves tubular secretion and reabsorption in addition to glomerular ...Renal tubular secretion of MTX has been thought to be a major site of interaction with other drugs (Takeda et ...from cells ...
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Erythropoietin in polycystic kidneys
... with proximal tubular ...stroma cells of the cyst walls by an in situ hybridization ...interstitial cells juxtaposed to proximal tubular cysts may produce EPO independent of the ...
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