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Proximal tubules

Administration of atrial natriuretic factor inhibits sodium coupled transport in proximal tubules

Administration of atrial natriuretic factor inhibits sodium coupled transport in proximal tubules

... cotransported with Na+ in the proximal tubules of rats. Synthetic ANF peptide consisting of 26 amino acids, 4 micrograms/kg body wt/h, or vehicle in controls, was infused to surgically ...

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Renin and renin mRNA in proximal tubules of the rat kidney

Renin and renin mRNA in proximal tubules of the rat kidney

... in proximal tubules of rat kidneys, and to determine the effect of converting enzyme inhibition (CEI) on proximal tubule renin gene ...expression. Proximal convoluted tubules (PCT), ...

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Relationship between Para aminohippurate Secretion and Cellular Morphology in Rabbit Proximal Tubules

Relationship between Para aminohippurate Secretion and Cellular Morphology in Rabbit Proximal Tubules

... aminohippurate (PAH) secretion is ~threefold greater in the straight segment, or pars recta, than in the convoluted segment, or pars convoluta. However, the possibility that the site of maximal PAH secretion might be ...

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Characteristics of salt and water transport in superficial and juxtamedullary straight segments of proximal tubules

Characteristics of salt and water transport in superficial and juxtamedullary straight segments of proximal tubules

... The purpose of the present studies was to characterize the nature of salt and water transport out of the superficial (SF) and juxtamedullary (JM) straight segments of rabbit proximal tubules as examined by ...

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The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration

The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration

... renal tubules remains a major challenge because of the glomerular filtration barrier, which effectively excludes conventional size ...which proximal tubule–selective Dps nanocages can limit the degree of ...

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Evidence for beta adrenoceptors in proximal tubules  Isoproterenol sensitive adenylate cyclase in pars recta of canine nephron

Evidence for beta adrenoceptors in proximal tubules Isoproterenol sensitive adenylate cyclase in pars recta of canine nephron

... of proximal tubules by acting on ...of proximal tubules of rat, rabbit, or mouse ...in proximal convoluted tubules (PCT), proximal straight tubules (PST), and in ...

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Activation of potassium channels contributes to hypoxic injury in proximal tubules

Activation of potassium channels contributes to hypoxic injury in proximal tubules

... The mechanisms responsible for the loss of cell potassium during renal ischemia are poorly understood. The present studies examined the hypothesis that potassium channels are activated as an early response to hypoxia and ...

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Role of cytosolic calcium independent plasmalogen selective phospholipase A2 in hypoxic injury to rabbit proximal tubules

Role of cytosolic calcium independent plasmalogen selective phospholipase A2 in hypoxic injury to rabbit proximal tubules

... rabbit proximal tubules and examined whether inhibition of calcium-independent PLA2 activity is associated with a cytoprotective ...rabbit proximal tubules to hypoxia for 5 min resulted in at ...

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Intracellular glutathione in the protection from anoxic injury in renal proximal tubules

Intracellular glutathione in the protection from anoxic injury in renal proximal tubules

... GSH tubules were protected from plasma membrane damage during anoxia by exogenous addition of 1 mM GSH or GLY, reducing lactate dehydrogenase (LDH) release from 42 +/- 7 to 14 +/- 1 and 10 +/- 1%, ...GSH ...

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Micropuncture study of the effect of various diuretics on sodium reabsorption by the proximal tubules of the dog

Micropuncture study of the effect of various diuretics on sodium reabsorption by the proximal tubules of the dog

... Acute saline infusion, however, markedly depressed sodium reabsorption by the proximal tubule, an effect that was independent of changes in glomerular filtration rate and occurred in the[r] ...

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Isovolumetric regulation of isolated S2 proximal tubules in anisotonic media

Isovolumetric regulation of isolated S2 proximal tubules in anisotonic media

... gradually changed over a range from 110 to 480 mosM. At 1.5 mosM/min, cell volume remained constant between 167 +/- 9 and 361 +/- 7 mosM, a phenomenon termed isovolumetric regulation (IVR). Cells lost intracellular ...

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Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice

Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice

... the proximal tubule, previous studies have not discriminated between the roles of extrarenal and intrarenal dopamine in the overall regulation of renal ...kidney proximal tubules (referred to herein ...

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Renoprotective effect of red grape (Vitis vinifera L.) juice and dark raisins against hypercholesterolaemia-induced tubular renal affection in albino rats

Renoprotective effect of red grape (Vitis vinifera L.) juice and dark raisins against hypercholesterolaemia-induced tubular renal affection in albino rats

... Proximal tubules are the first parts of renal tubules where most of the filtered substances are reabsorbed back to ...such tubules will result in Figure ...intact proximal ...

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Development of Severe Hyponatremia due to Salt-Losing Nephropathy after Esophagectomy for Esophageal Cancer

Development of Severe Hyponatremia due to Salt-Losing Nephropathy after Esophagectomy for Esophageal Cancer

... that proximal tubular dysfunction existed in the present ...suggesting proximal tubular injury and ...the proximal tubule and is indirectly coupled to sodium reabsorption ...because proximal ...

5

Acquired Fanconi syndrome in patients with Legionella pneumonia

Acquired Fanconi syndrome in patients with Legionella pneumonia

... renal proximal tubules presenting decreased tubular reabsorption of phosphate (%TRP), increased fractional excretion of potassium (FEK) and uric acid (FEUA), low-molecular-weight proteinuria, ...

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Transforming growth Factor Beta 1 drives a switch in connexin mediated cell to cell communication in tubular cells of the diabetic kidney

Transforming growth Factor Beta 1 drives a switch in connexin mediated cell to cell communication in tubular cells of the diabetic kidney

... the proximal renal ...primary proximal tubule epithelial cells (hPTECs) and model epithelial cells from human renal proximal tubules (HK2) cultured in either low glucose (5mmol/L) ± TGFβ1 ...

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KCl co transport across the basolateral membrane of rabbit renal proximal straight tubules

KCl co transport across the basolateral membrane of rabbit renal proximal straight tubules

... renal proximal tubules reabsorb large amounts of ...renal proximal tubule, isolated rabbit proximal straight tubules (S2 segment) were perfused in vitro, and intracellular activities of ...

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Renin expression in renal proximal tubule

Renin expression in renal proximal tubule

... the proximal tubule could not distinguish synthesized renin from renin trapped from the glomerular ...rabbit proximal tubule cells in primary culture and renin mRNA in microdissected proximal ...of ...

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Ammonia production by individual segments of the rat nephron

Ammonia production by individual segments of the rat nephron

... the proximal convoluted (S-1), proximal straight (S-3), and distal convoluted tubules, and lowest (less than or equal to 2) in cortical and medullary collecting ducts and thin descending ...the ...

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Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation

Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation

... of proximal tubules while repressing the formation of distal tubules (Cheng et ...distal tubules and inhibit the formation of proximal ...( proximal tubule), Slc12a1 (loop of ...

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