Pulmonary epithelial cells
Interleukin-1 regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages
... 2012 Interleukin-1 regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells a[r] ...
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CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells
... inhibit pulmonary cell proliferation, resulting in respiratory ...of pulmonary epithelial cells during embryonic ...II cells show increased ...II cells and an absence of alveolar ...
10
CXCL5 secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis
... load (10). Investigations on propensities of PMNs to eradicate M. tuberculosis generated conflicting results (11). Some reported mycobactericidal activities of human PMNs (12–15), while others demonstrated that human ...
16
The increase of microRNA-21 during lung fibrosis and its contribution to epithelial-mesenchymal transition in pulmonary epithelial cells
... in epithelial cells in normal lungs, is down-regulated in the lung tissues of IPF patients ...in epithelial cells and increased collagen deposition in mouse lungs ...an epithelial ...
13
Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase
... sorted cells were resuspended in NuPage buffer (Invitrogen, Carlsbad, CA) and protein concentra- tions were determined using the DC protein assay (Bio- Rad, Hercules, ...
11
CCR10+ epithelial cells from idiopathic pulmonary fibrosis lungs drive remodeling
... Physiologically, pulmonary epithelial cells were observed to promote fibroblast quiescence (50, 51); however, under injury conditions, these cells can promote fibroblast proliferation and ...
22
Prevention of bleomycin induced pulmonary fibrosis after adenovirus mediated transfer of the bacterial bleomycin resistance gene
... the pulmonary toxicity of bleomycin, but have not led to a useful clinical treatment because of their adverse effects on other ...in pulmonary epithelial cells in the lungs are protected ...
11
Epithelial Sodium Channels in Pulmonary Epithelial Progenitor and Stem Cells
... alveolar epithelial injury, can replenish cell lineages in the alveolus ...club cells, distal airway stem cells (DASCs) and basal cells contribute to replenishing other pulmonary ...
5
Stimulant-Dependent Modulation of Cytokines and Chemokines by Airway Epithelial Cells: Cross Talk between Pulmonary Epithelial and Peripheral Blood Mononuclear Cells
... unresponsive epithelial cells to SE and LPS may amplify local immune responses to SE and LPS in different ways, depending on the insulting ...the cells that produce these cyto- kines are critical ...
6
Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids
... airway epithelial cells may be particu- larly relevant to allergic diseases, as eotaxin immunoreactivity is detectable in the epithelial cells of nasal polyps that are infil- trated with ...
8
Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation
... myeloid cells had no impact on pulmonary inflammatory responses in our in vivo model, which was unexpected, both because isolated alveolar macrophages lacking REV-ERBα show exaggerated LPS responses ex ...
17
Immunohistochemical detection and regulation of α5nicotinic acetylcholine receptor (nAChR) subunits by FoxA2 during mouse lung organogenesis
... primary antibody at 4°C overnight. Control sections were incubated in blocking serum alone. After overnight incubation with primary antibody, all sections (including controls) were washed and positive staining was ...
11
Airway Epithelial Cell Function and Respiratory Host Defense in Chronic Obstructive Pulmonary Disease
... secretory cells (i.e., goblet and club cells located in the upper and lower airways, respectively) and basal ...Airway epithelial host defense mechanisms include constitutive host defense mechanisms, ...
9
Resveratrol as a potential therapeutic drug for respiratory system diseases
... Abstract: Respiratory system diseases are common and major ailments that seriously endanger human health. Resveratrol, a polyphenolic phytoalexin, is considered an anti-inflammatory, antioxidant, and anticancer agent. ...
8
Robust hypergraph regularized non-negative matrix factorization for sample clustering and feature selection in multi-view gene expression data
... The Cancer Genome Atlas (TCGA) program applies high-throughput sequencing technology to under- stand the mechanisms of the occurrence and devel- opment of cancer cells [20]. In this experiment, we testify the ...
10
Biomarkers for epithelial mesenchymal transitions
... Somatic cells that change from one mature phenotype to another exhibit the property of ...that epithelial and endothelial cells enjoy some of this plasticity, which is easily demonstrated by study- ...
10
Endoplasmic reticulum stress mediates house dust mite-induced airway epithelial apoptosis and fibrosis
... mammalian cells, misfolded proteins are sensed by three ER transmembrane proteins: Inosi- tol Requiring Enzyme 1 (IRE1), activating transcription factor 6 (ATF6), and PKR-like ER kinase (PERK) ...II ...
12
A(H7N9) Virus Results in Early Induction of Proinflammatory Cytokine Responses in both Human Lung Epithelial and Endothelial Cells and Shows Increased Human Adaptation Compared with Avian H5N1 Virus
... Calu-3 cells (10) ...Calu-3 cells were infected with different subtype viruses and the production of proinflammatory cytokines and chemokines at 24 h ...Calu-3 cells compared with that in uninfected ...
13
Essential roles of the Fas Fas ligand pathway in the development of pulmonary fibrosis
... TUNEL-positive cells, we consider that the hFas-Fc administration at day 7 or 10 could ame- liorate the pathological grade and apoptosis at day ...tumor cells can induce a granulocyte- mediated rejection ...
8
Circadian clock component REV ERBα controls homeostatic regulation of pulmonary inflammation
... these cells, impacts on oxidative stress responses, suppresses both REV-ERBα and β expression, and both abolishes time-of-day variation and augments pulmonary neutrophilic inflammation ...
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