Pulmonary vascular remodeling
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling
... the vascular remodeling associated with chronic hypoxia and other experimental manifesta- tions of PH [10-14]; these findings have accelerated investigation into the potential mechanisms of inflam- mation ...
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Vascular endothelial growth factor as a non-invasive marker of pulmonary vascular remodeling in patients with bronchitis-type of COPD
... of pulmonary vascular remodeling will be required to be widely used in the clinical investigation in this ...the vascular remodeling in pulmo- nary arteries with bronchitis-type of COPD ...
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Activation of Nrf2 Attenuates Pulmonary Vascular Remodeling via Inhibiting Endothelial-to-Mesenchymal Transition: an Insight from a Plant Polyphenol
... in pulmonary vascular ...against pulmonary arterial ...of pulmonary artery remodeling in MCT-induced PAH in rats ...MCT-induced pulmonary hypertension ...
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Hypoxia induced pulmonary vascular remodeling: a model for what human disease?
... trigger pulmonary vascular remodeling, may point toward such a final ...that vascular remodeling in the monocrotaline model could be blocked by inhibiting ECM turnover or by blocking ...
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Role of SOD3 in silica-related lung fibrosis and pulmonary vascular remodeling
... of pulmonary vascular remodeling associated with chronic lung diseases is not well ...of vascular remodeling and pulmonary hypertension in this ...more pulmonary nodules, ...
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The association of neuron-derived orphan receptor 1 with pulmonary vascular remodeling in COPD patients
... evaluating pulmonary vascular remodeling. As expected, the pulmonary vascular wall thickness and muscularized vessels ratio in COPD patient with hypoxemia were both significantly higher ...
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An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease
... of pulmonary vascular remodeling characterized by abnormal growth and thickening of the intimal, medial, and adventitial layers of the precapillary vascular wall and eventual right ventricular ...
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Mesenchymal stromal cell-derived exosomes improve pulmonary hypertension through inhibition of pulmonary vascular remodeling
... PH pulmonary vascular remodeling were associated with up-regulation wnt5a expres- ...and vascular remodeling [28, ...in vascular remodeling and the fibrotic lung disease ...
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Pregnancy-associated plasma protein A – a new indicator of pulmonary vascular remodeling in chronic thromboembolic pulmonary hypertension?
... thromboembolic pulmonary hypertension (CTEPH) insufficient thrombus resolution and vascular remodeling lead to chronic obstructions of the pulmon- ary arteries ...impaired pulmonary ...
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The role of tissue factor and autophagy in pulmonary vascular remodeling in a rat model for chronic thromboembolic pulmonary hypertension
... of vascular endothelial growth factor through the mitogen-activated protein kinase (MAPK) sig- nal transduction pathway and thus promote vascular re- modeling including endothelial cell proliferation and ...
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Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice
... the vascular media which is augmented by increased shear stress in the pul- monary bed after pneumoctomy ...preventing pulmonary hypertension induced by a pathophysiologic ...
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Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension
... resident vascular cells to promote the development and progres- sion of ...progressive vascular remodeling and promote the development of ...propagates pulmonary vascular ...
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The role of vascular injury and hemodynamics in rat pulmonary artery remodeling
... of pulmonary vascular remodeling in primary pulmonary hyper- tension as well as provide an explanation for the clinical obser- vation that pulmonary artery neointimal formation is only ...
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Effects of chrysin (5,7-dihydroxyflavone) on vascular remodeling in hypoxia-induced pulmonary hypertension in rats
... on vascular remodeling was investigated in hypoxia-induced PH ...for pulmonary vascular remodeling and right ventricle hypertrophy were measured by vascular medial wall thickness ...
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Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia inducible factor 1α
... in pulmonary hypertension can- not be ruled ...on pulmonary vascular remodeling than on ery- thropoiesis, suggesting that the latter effect was not suf- ficient to explain the ...
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Ectopic upregulation of membrane bound IL6R drives vascular remodeling in pulmonary arterial hypertension
... cause pulmonary vascular remodeling and pulmonary hypertension (PH) or to exaggerate the pulmonary hypertensive response to chronic hypoxia (9, ...monary vascular ...
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Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
... the pulmonary smooth muscle cells hyperplasia found by Crawford et ...The pulmonary vascular remodeling seemed to have ceded when antibiotics pre- vented the ...
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Fluoxetine Protects against Big Endothelin 1 Induced Anti Apoptosis by Rescuing Kv1 5 Channels in Human Pulmonary Arterial Smooth Muscle Cells
... Pulmonary Kv channels are thought to play a crucial role in the maintenance of resting membrane potentials, and subsequently the vascular tone of pulmonary arteries. Alter- ations in Kv channel ...
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Influence of gender in monocrotaline and chronic hypoxia induced pulmonary hypertension in obese rats and mice
... ary vascular remodeling in MCT treated female ...to pulmonary vascular remodeling and right ven- tricular dysfunction after MCT ...
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Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension
... pulmonary vasodilation [28]. Extensive work from the field of left-sided heart failure has already revealed that in addition to vasodilation, cardiac unloading through blood volume reduction via RAAS inhibition ...
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