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Pyridazine Derivatives

Electrochemical, DFT and Mont Carlo Simulations Studies to Evaluate the Inhibition Effect of Novel Pyridazine Derivatives on Iron Pitting Corrosion in 3.5 % NaCl

Electrochemical, DFT and Mont Carlo Simulations Studies to Evaluate the Inhibition Effect of Novel Pyridazine Derivatives on Iron Pitting Corrosion in 3.5 % NaCl

... S-alkylated pyridazine derivatives with different side chain ...parent pyridazine (PPS) using electrochemical measurements and theoretical ...studied pyridazine derivatives shift both ...

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Theoretical assessment of corrosion inhibition performance of some pyridazine derivatives on mild steel

Theoretical assessment of corrosion inhibition performance of some pyridazine derivatives on mild steel

... The pyridazine and their derivatives are reported to exhibit a broad range of biological activity, such as analgesic [21], antibacterial [22], anti-inflammatory [23], antihypertensive properties ...new ...

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Comparative Inhibition Study of New Synthesised Pyridazine Derivatives Towards Mild Steel Corrosion in Hydrochloric Acid. Part-II : Thermodynamic Proprieties

Comparative Inhibition Study of New Synthesised Pyridazine Derivatives Towards Mild Steel Corrosion in Hydrochloric Acid. Part-II : Thermodynamic Proprieties

... synthesised pyridazine derivatives (P1, P2, P3 and P4) as a steel corrosion inhibitors in 1 M hydrochloric acid, were measured by the weight loss method, in the range of temperatures from 303 to 353 ...the ...

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Effect of New Synthesised Pyridazine Derivatives on the Electrochemical Behaviour of Mild Steel in 1M HCl Solution: Part-1

Effect of New Synthesised Pyridazine Derivatives on the Electrochemical Behaviour of Mild Steel in 1M HCl Solution: Part-1

... The aggressive solution (1M HCl) was prepared by dilution of analytical grade 37% HCl with bidistilled water. Prior to all measurements, the steel samples were polished with different emery paper up to 1200 grade and ...

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Investigation of Newly Pyridazine Derivatives as Corrosion Inhibitors in Molar hydrochloric Acid. Part III: Computational Calculations

Investigation of Newly Pyridazine Derivatives as Corrosion Inhibitors in Molar hydrochloric Acid. Part III: Computational Calculations

... The main objective of this work was to investigate computationally, in gas and aqueous phases, using DFT at B3LYP/6-31G** level of theory, four newly synthesized pyridazine derivatives denoted hereafter P1, ...

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An Investigation of Two Novel Pyridazine Derivatives as Corrosion Inhibitor for C38 Steel in 1.0 M HCl

An Investigation of Two Novel Pyridazine Derivatives as Corrosion Inhibitor for C38 Steel in 1.0 M HCl

... the pyridazine derivatives containing sulphur atom offer good inhibitory effect of the corrosion of steel in acidic media ...of pyridazine compounds is based on their much known pharmaceutical ...

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Dimethylformamide Dimethyl Acetal (DMFDMA) in Heterocyclic Synthesis: Synthesis of Polysubstituted  Pyridines, Pyrimidines, Pyridazine and Their Fused Derivatives

Dimethylformamide Dimethyl Acetal (DMFDMA) in Heterocyclic Synthesis: Synthesis of Polysubstituted Pyridines, Pyrimidines, Pyridazine and Their Fused Derivatives

... The reaction of malononitrile dimer 8 with diazo- nium salts of aromatic amines 20a-e furnished the corre- sponding pyridazine derivatives 21a-e. The structure of the isolated products was confirmed by ...

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Drug design, development and biological screening of pyridazine derivatives

Drug design, development and biological screening of pyridazine derivatives

... Pyrazolo pyridazine derivatives have been synthesised by the Intramolecular cyclisation of the corresponding phenyl hydrazones acquired from diazotization of substituted Anilines followed by Friedel crafts ...

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Synthesis, anti microbial evaluation and cytotoxicity bioassay of some synthesized novel pyridazine derivatives comparison to standard drugs

Synthesis, anti microbial evaluation and cytotoxicity bioassay of some synthesized novel pyridazine derivatives comparison to standard drugs

... Pyridazine derivatives were used in many research fields due to their structure, stability and reactivity and their tendency to form stable compounds with useful biological properties ...Pyrazolopyridazines ...

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Comparative Study of new Pyridazine Derivatives Towards Corrosion of Copper in Nitric Acid: Part-1

Comparative Study of new Pyridazine Derivatives Towards Corrosion of Copper in Nitric Acid: Part-1

... The corrosion inhibition by some pyridazines derivatives has been studied by several researchers [16-20]. Results obtained show that they act as cathodic inhibitors without modifying the mechanism of hydrogen ...

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Synthesis and In Vitro Anticancer Evaluation of some Acyclic N  and S nucleosides of Pyridazine Derivatives

Synthesis and In Vitro Anticancer Evaluation of some Acyclic N and S nucleosides of Pyridazine Derivatives

... In this work some N- and S-acyclic nucleoside of pyridazine derivatives were prepared to start with 4,6-diphenyl-2H-pyridazin-3-one (1) [12] as the key compound for this study (Scheme 1). When the sodium ...

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Molecular Modelling, Synthesis and Evaluation of Pyridazine Derivatives as Potent Anti-Cancer Agents

Molecular Modelling, Synthesis and Evaluation of Pyridazine Derivatives as Potent Anti-Cancer Agents

... 25. Marta Szumilak et al., [42] synthesised new polyamine derivatives containing dimeric quinoline, cinnoline[25] and phthalimide moieties. The new compounds were obtained according to known procedures. Their ...

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trans Tetra­aqua­bis­­(pyridazine 4 car­box­yl­ato κO)magnesium(II) dihydrate

trans Tetra­aqua­bis­­(pyridazine 4 car­box­yl­ato κO)magnesium(II) dihydrate

... with pyridazine-3-carboxylate and water ligands (Gryz et ...The pyridazine ring is planar with ...and pyridazine-N atoms in adjacent monomers as ...with pyridazine-3-carboxylate ...

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Study on the Synthesis, Characterization and Antimicrobial studies of the Transition Metal Complexes of the Novel Mannich Base Derived from Pyridazine Derivative

Study on the Synthesis, Characterization and Antimicrobial studies of the Transition Metal Complexes of the Novel Mannich Base Derived from Pyridazine Derivative

... acid derivatives. Part IV: mannich base derivatives and its activities on the electrically stimulated guinea-pig ileum preparation,” Journal of the Brazilian Chemical Society, ...

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catena Poly­[mercury(II) di μ chloro μ pyridazine κ2N:N′]

catena Poly­[mercury(II) di μ chloro μ pyridazine κ2N:N′]

... centers symmetrically bridged by chloride, with four equal HgÐCl distances of 2.6819 (16) AÊ. Neighboring mercuric centers are connected by the two adjacent N atoms of pyrid- azine molecules, with two HgÐN distances of ...

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Bis(pyridazine κN)bis­­(seleno­cyanato κN)zinc

Bis(pyridazine κN)bis­­(seleno­cyanato κN)zinc

... The title compound is isotypic to its thiocyanato analogon reported recently (Bhosekar et al. , 2010). In the crystal structure the zinc atoms are surrounded by two N-atoms of two symmetry equivalent pyridazine ...

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3,4,6 Tris­(pyrazol 1 yl)­pyridazine

3,4,6 Tris­(pyrazol 1 yl)­pyridazine

... An analysis of the extended structure reveals the existence of a very short offset face-to-face (off) π – π interaction involving the pyridazine and 6-substituted pyrazole ring of adjacent molecules (Fig. 2). The ...

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Synthesis of some new Indeno[1,2 e]pyrazolo[5,1 c] 1,2,4 triazin 6 one and Indeno[2,1 c]pyridazine 4 carbonitrile Derivatives

Synthesis of some new Indeno[1,2 e]pyrazolo[5,1 c] 1,2,4 triazin 6 one and Indeno[2,1 c]pyridazine 4 carbonitrile Derivatives

... Diazonium chlorides of 5-amino-3-methypyra- zole 1a and 5-amino-4-phenylpyrazole 1b cou- pled with 1,3-indanedione 2 and led to the for- mation of acyclic hydrazone 3a and a cyclic product indenopyrazolotriazine 4b ...

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Bis(μ pyridazine 3 carboxyl­ato κ2O:O′)bis­­[aqua­dioxido(pyridazine 3 carboxyl­ato κ2N2,O)uranium(VI)] dihydrate

Bis(μ pyridazine 3 carboxyl­ato κ2O:O′)bis­­[aqua­dioxido(pyridazine 3 carboxyl­ato κ2N2,O)uranium(VI)] dihydrate

... of pyridazine–3–carboxylic acid and 1 mmol of uranyl nitrate hexahydrate, respectively, were mixed and boiled for two hours with constant stirring and left to crystallize at room ...

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3 p Tolyl­imidazo[1,2 b]pyridazine

3 p Tolyl­imidazo[1,2 b]pyridazine

... as bases. Its structure (Fig. 1) is reported here. The fused pyridazine and imidazole rings are individually planar (r.m.s. deviations = 0.0103 and 0.0017 A ˚ , respectively) and form a single planar unit, with a ...

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