PYRIMIDIN-2-AMINE
Synthesis and Evaluation of 4 (1h Benzimidazol 2 Yl) 6 (2 Chloroquinolin 3 Yl) Pyrimidin 2 Amine as Potent Anthelmintic Agents
... A new series of compounds of 4-(1H-benzimidazol-2-yl)-6-(2-chloroquinolin-3-yl)pyrimidin-2-amine (Va-k) were synthesized. The synthesized compounds were additionally screened for ...
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Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4′-(1,4-phenylene)bis(pyrimidin-2-amine) derivatives
... Preliminary materials (glasswares, chemicals etc.) for the research work were obtained from commercial sources [Loba Chemie, Pvt Ltd. Mumbai, India; Central Drug House (CDH) Pvt. Ltd., New Delhi, India and HiMedia ...
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Quantum Chemical Characterization of Hydrogen Bonding Sites in Three 4 (4 Halo Phenyl) 6 (Furan 2 yl) Pyrimidin 2 Amine Derivatives
... 4-(4-fluorophenyl)-6-(furan-2-yl) pyrimidin-2-amine (DP-1), 4-(4-ch- lorophenyl)-6-(furan-2-yl) pyrimidin-2-amine (DP-2) and 4-(4-bromophenyl)- ...
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Di μ2 methanolato bis[tetrakis(pyrimidin 2 amine κN1)cobalt(II)] bis(tetrafluoroborate)
... 49.8 mg) and pyrimidin-2-amine (0.2 mmol, 37.6 mg) were dissolved in methanol (20 ml). A solution of sodium fluoroborate (0.1 mmol, 10.9 mg) in water (3 ml) was then added. The mixture was stirred ...
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Pyrimidin 2 amine–1 phenylcyclopentane 1 carboxylic acid (1/1)
... of pyrimidin-2-amine and one molecule of 1-phenyl- cyclopentane-1-carboxylic acid in the crystallographic asymmetric unit ...Two pyrimidin-2-amine molecules that are related by ...
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“Synthesis and Antitubercular Activity of Some Novel {1[(1phenylethylidene) amino] naphtho [2,1-B]furan-2- yl}4-substituted pyrimidin-2-amine Derivatives” by Riddhi Madhu, N.M. Maheta, T.Y. Pasha, Sandip Patel, India.
... yl}4-Substituted pyrimidin-2-amine derivatives by condensation of Chalcone and guanidine in presence of ...yl}4-Substituted pyrimidin-2-amine derivatives has been developed which ...
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4 (4 Fluorophenyl) 6 (2 furyl)pyrimidin 2 amine
... planar and in the crystal structure they form dimers via hydrogen bonds, involving pyrimidinyl N atoms and amino H atoms, about inversion centers. The centroids of the furyl and pyrimidinyl rings are separated by 3.489 ...
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4,6 Dimethylpyrimidin 2 amine
... C6 0.0566 (19) 0.074 (2) 0.092 (2) −0.0037 (16) −0.0060 (16) −0.0336 (19) C7 0.0457 (15) 0.0527 (16) 0.0479 (15) −0.0060 (13) 0.0017 (12) 0.0012 (13) C8 0.0515 (16) 0.0489 (16) 0.0639 (18) −0.0029 (13) ...
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4 (3,4 Dihydro β carbolin 1 yl)pyrimidin 2 amine
... The molecule of Accanthomine A (I) is approximately planar; the amino group of the five-membered ring is hydrogen- bond donor to a nitrogen acceptor of the pyrimidyl ring (Fig. 1). The amino group of the pyrimidyl ring ...
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4 Methyl 6 (piperidin 1 yl)pyrimidin 2 amine
... In the crystal structure, the molecules are linked to one another through N—H···N hydrogen bonds generating R228 ring patterns Bernstein et al., 1995 forming inversion related dimers.. T[r] ...
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Synthesis and crystal structure of N (4 chlorophenyl) 5,7 dimethyl 1,2,4 triazolo[1,5 a]pyrimidin 2 amine
... Crystal data, data collection and structure refinement details are summarized in Table 2. All H atoms bonded to C atoms were placed in geometrically idealized positions according to hybridization and constrained ...
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1,2 Bis(pyrimidin 2 ylsulfanyl)ethane
... As shown in Fig. 1, the molecule adopts an anti conformation (Goodgame et al., 1999) with a pseudo-torsion angle C4 —S1···S2—C7 of −174.9 (2)°. The pyrimidine rings (N1/C1–C3/N2/C4 and N3/C7/N4/C8–C10), with a ...
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trans 1,4 Bis(pyrimidin 2 ylsulfanyl)but 2 ene
... A large number of complexes of dithioether ligands containing N-heterocyclic systems have been synthesized and investigated because of their interesting structures and the properties of their metal complexes (Hong et ...
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6 Methylpyridin 2 amine
... strengths and directional propensities of its intermolecular non-bonding interactions and to generate in future the chiral molecular co-crystals on the basis of this compound. The structures of several interesting series ...
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3 Chloropyridin 2 amine
... ethyl 2-(3-chloropyridin-2-yl)-5-oxopyr- azolidine-3-carboxylate, an intermediate in the synthesis of the insecticide chlorantraniliprole (systematic name 3-bromo- ...
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1,3 Bis(pyrimidin 2 ylsulfanyl)propan 2 one
... In recent years, N-containing heterocyclic thioethers linked by various aryl or alkyl groups have been widely exploited in metal-organic self-assembly as multitopic bridging ligands, and several unique structural motifs ...
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One Step Iodine Promoted Synthesis of Imidazol-2-one and Pyrimidin-2-one
... and pyrimidin-2-ones/thiones have been reported by cyclisation of urea, thiourea, guanidine with aldehydes/ketones in presence of molecular iodine in ethanol by grinding in mortar by ...
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1 (2 Chlorobenzoyl) 3 (pyrimidin 2 yl)thiourea
... In continuation of our work on the structural and coordination chemistry of N,N′-disubstituted thioureas (Rauf et al., 2012) the structure of the title compound (Fig. 1) is described in this article. The bond lengths and ...
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(R) N Methyl 4 [2 (methylsulfanyl)pyrimidin 4 yl] 1 (tetrahydrofuran 3 yl) 1H pyrazol 5 amine
... A solution of -(2-(methylsulfanyl)pyrimidin-4-yl)-1-(tetrahydrofuran-2-yl)-1H-pyrazol-5-amine (8.32 g, 30.0 mmol) in anhydrous THF (80 ml) was added dropwise to a suspension of hexane-washed ...
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3 Benzyloxypyridin 2 amine
... C6 0.0676 (17) 0.0540 (15) 0.0673 (17) 0.0115 (12) −0.0057 (13) 0.0004 (12) C7 0.0581 (15) 0.0411 (12) 0.0645 (15) 0.0025 (11) −0.0048 (12) 0.0068 (11) C8 0.0588 (15) 0.0680 (16) 0.0709 (17) 0.0074 (13) −0.0004 (13) ...
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