QUINAZOLIN-4(3H)-ONE
![Molecular docking study and antiviral evaluation of 2-thioxo-benzo[g]quinazolin-4(3H)-one derivatives](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
Molecular docking study and antiviral evaluation of 2-thioxo-benzo[g]quinazolin-4(3H)-one derivatives
... Background: The persistent appearance of viral strains that causes a resistant viral infection has led to continuous tri‑ als for the design and development of novel antiviral compounds. Benzoquinazoline compounds have ...
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Environmentally benign synthetic approach and antimicrobial activity of Co(II) complexes of quinazolin 4(3H) one derived bidentate schiff bases
... 3-phenyl-2-propyl- quinazolin-4(3H)-one with semicarbazide / thiosemicarbazide) and theircomplexes with Co(II)) ion and to illustrate their geometrical structures by using different techniques ...
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Electron Impact Ionization Mass Spectra of 3-Amino 5,6-Dimethoxyl-2-Methyl Quinazolin-4-(3H)-One Derivative
... Abstract: Background: The synthesis of novel heterocyclic derivatives has attracted considerable attention. The explosive growth of heterocyclic chemistry is emphasized by the large number of research publications, ...
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Microwave Assisted One Pot Synthesis of 2, 3 Di Substituted Quinazolin 4 (3h) Ones and Their Potential Biological Activity
... The 4-(3H)-quinazolinones are the formal condensation products of Anthranilic acid and amides, and they can also be prepared in this fashion through the Niementowski quinazolinone synthesis ...
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3 (2 Aminoethyl) 2 (4 chloroanilino)quinazolin 4(3H) one methanol 0 75 solvate
... and one and a half methanol molecules. One of the methanol molecules is disordered over two positions with equal ...two quinazolin-4(3H)-one molecules are essentially the same, ...
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Synthesis, Characterisation and Anti-inflammatory Activity of some Novel Quinazolin-4-(3h)-one Analogues
... phenyl) quinazolin-4(3H)-one (Q1) and 3-(4-Methyl phenyl) quinazolin-4(3H)-one (Q2) synthesized by reacting with substituted ...phenyl) ...
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Design, synthesis, antiviral bioactivities and interaction mechanisms of penta-1,4-diene-3-one oxime ether derivatives containing a quinazolin-4(3H)-one scaffold
... [17], quinazolin-4(3H)-one [18], 1,3,4-thiadiazole [19], 1,3,4-oxadiazole [20], emodin [21], glucopyranoside [22], oxime ether [23], oxime ester [15], pyridine [24], rutin [25], ...
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Synthesis and antimicrobial screening of some new N3 substituted derivatives of quinazolin 4(3H)one
... Quinazolin-4-one-3-yl-propan-2-one (2) was prepared by N-alkylation of Quinazolin-4(3H)one 1. The treatment of compound 2 with hydrazine hydrate yielded hydrazine ...
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Synthesis, characterization and antimicrobial activity of new quinazolin 4(3H) one schiff base derivatives
... with 4-fluoro aniline in situ to replace the chloro group of the acid chloride with 4-fluoro ...2-chloromethyl 4(3H)-quinazolinone 2 with 5-nitro indole in the presence of potassium carbonate ...
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Expeditious Synthesis and Spectroscopic Characterization of 2-Methyl-3-Substituted-Quinazolin-4(3H)-one Derivatives
... 2-methyl-3-substituted quinazolin-4(3H)-one derivatives 8a-q was herein synthesized from synthetic conversion of anthranilic acid to 2-methyl-4H-3,1-benzoxazi-4-one, 7 which was ...
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Synthesis and antibacterial activity of 3-amino-6-iodo-2-methyl quinazolin 4-(3H)-one and 6-iodo-2-methyl-4H-benzo [D] [1, 3] oxazin-4-one
... of 4(3H)-quinazolinone derivatives, 2,3-disubstituted derivative of quinazoline- 4-one were synthesized via the interaction of the benzoxazinone derivative with nitrogen nucleophile with the ...
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Crystal structure of 3 (4 hydroxyphenyl) 2 [(E) 2 phenylethenyl]quinazolin 4(3H) one
... (Fig. 4) gave 137 hits, while a search for substructure S2 (2-arylvinyl 3-aryl quinazolin-4(3H)-one skeleton, ...Fig. 4) gave only three hits: Nosova et ...of ...
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3 Methyl 2 (3,3,3 trichloro 2 hydroxypropyl)quinazolin 4(3H) one
... of quinazolin-4(3H)-one deriv- atives, see: Yang et ...of quinazolin-4(3H)-one derivatives, see: Shakhidoyatov ...of ...
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SYNTHESIS, CHARACTERIZATION AND ANTIFUNGAL ACTIVITY OF SOME QUINAZOLIN-4-ONE DERIVATIVES
... 3-(4-acetylphenyl)-6-iodo-2-thioxo-2,3-dihydro quinazolin-4-one in absolute ethanol, substituted benzaldehyde and 2% NaOH were added and refluxed for 10 ...
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SYNTHESIS AND CHARACTERIZATION OF 3 [(5 (2 NITROPHENYL) 1, 3, 4 OXADIAZOL 2 YL) METHYL AMINO] 2 METHYL QUINAZOLIN 4(3H) ONE
... 2. Proton Magnetic Resonance Spectrum: The 1 H NMR spectrum was recorded on JMR spectrometer using TMS as internal standard and DMSO as solvent. The 1 H NMR spectrum of compound IV shown in figure 2 and table 3 showed ...
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3 (2 Aminoethyl) 2 (4 fluoroanilino)quinazolin 4(3H) one
... To a solution of 2-ethoxycarbonyliminophosphorane (1.27 g, 3 mmol) in 10 ml anhydrous THF, 4-chlorophenyliso- cyanate (0.46 g, 3 mmol) was added dropwise at room temperature. The reaction mixture was left ...
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Utility of 2 Methyl quinazolin 4(3H) one in the Synthesis of Heterocyclic Compounds with Anticancer Activity
... through condensation of compound 8 with phenacyl chloride in ethanol, which afforded quinazolin-3-ium chlo- ride derivative 14 and imidazo[1,2-c]quinazoline derivative 15 according to the mechanism suggested in ...
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Synthesis, Antibacterial and invitro Antioxidant Activity of 2,3 Substituted Quinazolin 4(3H) ones
... Synthesis of 2-phenyl-3-{[1-thiophen-2-ylethylidene]amino}quinazolin-4(3H)-one (16-20). 3-amino-2-substitutedphenylquinazolin-4(3H)-ones (10mmol) was refluxed with 2-acetyl ...
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Green Synthesis and In Vitro Anti Oxidant Activity of 6-aryl-quinazolin-4(3H)-ones via Suzuki Cross Coupling
... Microwave-assisted Suzuki Cross-coupling reaction of 6-iodo-quinazolin-4-(3H)-one (1) is explored for the first time with a set of eight aryl boronic acid 2 to provide ...
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2 Ethyl 3 [(R) 2 phenylbutanamido]quinazolin 4(3H) one monohydrate
... Ia), 159.5 (s, C-2 of Ib), 159.3 (s, C-2 of Ia), 147.1 (s, C-8a of Ib), 147.0 (s, C-8a of Ia), 139.9 (s, C-1 of Ph of Ib), 139.6 (s, C-1 of Ph of Ia), 135.4 (d, C-7 of Ib), 135.3 (d, C-7 of Ia), 128.9 (d, C-3/C-5 of Ph ...
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