Quinolone Resistance
Frequency of Quinolone Resistance and qnrB and qnrC Genes in Clinical Isolates of Klebsiella pneumoniae
... mediated quinolone resistance (PMQR) was increasingly identified in Enterobacteriaceae family ...Plasmid-mediated quinolone resistance (PMQR) was first reported in 1998 from a Klebsiella ...
7
Quinolone Resistance Reversion by Targeting the SOS Response
... We first confirmed that the ΔrecA and lexA1 mutations produce the expected perturbations in the SOS response (significant differences were observed confirming suppression and hypoinduction of the SOS response, respectively) ...
12
Characterization of plasmid-mediated qnrA and qnrB genes among Enterobacteriaceae strains: quinolone resistance and ESBL production in Ismailia, Egypt
... Plasmid-mediated quinolone resistance genes (PMQR) are mainly associated with clinical isolates of Enterobacteriaceae and complicate treatment of infections caused by these isolates ...of quinolone ...
7
Prevalence of Plasmid-Mediated Quinolone Resistance in Multidrug-Resistant Gram Negative Bacilli in Egypt
... to quinolone has increased significantly and one of the most reasons is plasmid-mediated quinolone resistance ...of quinolone resistant Gram negative bacilli clinical isolates is ...
10
Rapid Determination of Quinolone Resistance in Acinetobacter spp
... Determination of susceptibility to quinolones. MICs of ciprofloxacin and levo- floxacin were determined by the broth microdilution method using cation-ad- justed Mueller-Hinton medium according to the Clinical and ...
7
The prevalence of plasmid-mediated quinolone resistance and ESBL-production in <em>Enterobacteriaceae </em>isolated from urinary tract infections
... qnrC were detected at low frequency. It has been shown that the presence of PMQR genes provides a favorable field for quinolone resistance. Our data indicated that aac(6 ′)-Ib-cr, oqxB, oqxA, and qnrB genes ...
8
Association between ESBLs Genes and Quinolone Resistance in Uropathogenic Escherichia coli Isolated from Patients with Urinary Tract Infection
... mediated quinolone resistance determinants qnr and aac (6′)-Ib-cr in Escherichia coli and Klebsiella pneumoniae producing extended- spectrum β-lactamases in ...mediated quinolone resistance: ...
9
The Prevalence of Plasmid-mediated Quinolone Resistance Genes in Escherichia coli Isolated from Hospital Wastewater Sources in Tehran, Iran
... the quinolone resistance and PMQR determinants among ...of quinolone-resistant ...of resistance such as QRDR, chang- es in expression of efflux pumps, or even novel mechanisms should also be ...
7
Detection of Quinolone Resistance in Staphylococcus aureus isolates in a tertiary care centre
... antibiotic resistance among pathogenic bacteria is a persistent issue in antibiotic therapy in health care and community ...use, resistance has already emerged in some species of bacteria and some clinical ...
108
Phenotypic and genotypic characteristics of Escherichia coli with non-susceptibility to quinolones isolated from environmental samples on pig farms
... (fluoro)quinolone resistance in Enterobacteriaceae, ...the Quinolone Resistance Determining Region (QRDR) of gyrA encoding DNA gyrase, and the acquisition of plasmid-mediated quinolone ...
12
Ciprofloxacin prophylaxis in high risk neutropenic patients: effects on outcomes, antimicrobial therapy and resistance
... of quinolone prophylaxis in neutropenic cancer patients has been associated with a reduction in the inci- dence of bacterial infections and mortality ...in quinolone resistance [5-7], as well as ...
7
Comparison of two DNA microarrays for detection of plasmid mediated antimicrobial resistance and virulence factor genes in clinical isolates of Enterobacteriaceae and non Enterobacteriaceae
... In total, nine E. coli isolates, two K. pneumoniae and four Enterobacter spp. and their duplicates generated successful hybridi- sation results. The remaining isolates and their duplicates failed to generate successful ...
6
Molecular analysis of multidrug resistance in clinical isolates of <em>Shigella </em>spp. from 2001–2010 in Kolkata, India: role of integrons, plasmids, and topoisomerase mutations
... drug resistance in Shigella, 95 clinical isolates of Shigella ...antibiotics. Resistance to nalidixic acid, trimethoprim, streptomycin, and co-trimoxazole was most common in this ...trimethoprim ...
16
Plasmid Mediated Fluoroquinolone Resistance Determinants in Clinical Isolates of Escherichia coli
... fluoroquinolones resistance are plasmid mediated quinolone ...fluoroquinolone resistance in gram-positive and gram-negative bacteria has emerged and increased ...of resistance to the other ...
6
The involvement of mutation in the serine 83 of quinolone resistant determining regions of the GyrA Gene in resistance to ciprofloxacin in Escherichia coli .
... bacterial resistance in Escherichia coli to ciprofloxacin makes difficult the treatment of infectious ...in quinolone resistance- determining region (QRDR) of A subunit of DNA gyrase and specially at ...
6
Newest data on fluoroquinolone resistance mechanism of Shigella flexneri isolates in Jiangsu Province of China
... the quinolone resistance-determining regions of gyrA, gyrB, parC and parE were performed using primers and conditions as previously described (Table 1) ...
8
High Proportion of Fluoroquinolone Resistant Mycobacterium tuberculosis Isolates with Novel Gyrase Polymorphisms and a gyrA Region Associated with Fluoroquinolone Susceptibility
... Fluoroquinolone resistance in Mycobacterium tuberculosis can be conferred by mutations in gyrA or ...the quinolone resistance-determining region (QRDR) of gyrA or gyrB is unclear, since such regions ...
8
Multi-Drug Resistant and Plasmid-Mediated Quinolone-Resistant Salmonella enterica isolated from Shellfish in Iko Creek, Nigeria
... of resistance genes between bacteria from shellfish, humans and animals through the food ...mediated resistance against the commonly used antimicrobials ...multi-drug resistance (MDR) and ...
8
A solution to combat aminoglycoside and quinolone resistant gram negative organisms
... and quinolone resistance among the collected isolates and to analyze the antibiotic susceptiblity patterns of various drugs against these isolates to find which drug offers the best solution against ...
6
Chromosomal and plasmid mediated fluoroquinolone resistance in human Salmonella enterica infection in Ghana
... Plasmid-mediated Quinolone Resistance; QRDR: Quinolone Resistance Determining Region; SIB: Swiss Institute of Bioinformatics; TSI: Triple Sugar Iron Agar; WHO: World Health ...
10