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Rab Proteins; Life cycle and Effector Interactions

Structural biology of arf and rab GTPases' effector recruitment and specificity

Structural biology of arf and rab GTPases' effector recruitment and specificity

... and Rab proteins, members of small GTPases superfamily, localize to specific subcellular compartments and regulate intracellular ...Arf/Rab:effector interactions, which includes ‘‘all- a ...

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Structure function analyses of the interactions between Rab11 and Rab14 small GTPases with their shared effector Rab coupling protein (RCP)

Structure function analyses of the interactions between Rab11 and Rab14 small GTPases with their shared effector Rab coupling protein (RCP)

... functional cycle is completed by re-inser- tion of Rab tails into ...of effector proteins. Rab structures consist of a six-stranded mixed ␤ -sheet flanked by five ␣ ...

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Interactions with Pocket Proteins Contribute to the Role of Human Papillomavirus Type 16 E7 in the Papillomavirus Life Cycle

Interactions with Pocket Proteins Contribute to the Role of Human Papillomavirus Type 16 E7 in the Papillomavirus Life Cycle

... “pocket proteins” p107 and ...HPV16 life cycle, which takes place in stratified squamous ...cell cycle and initiated a well-defined pattern of terminal ...pocket proteins but not its ...

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Vesicle transport in chloroplasts with emphasis on Rab proteins

Vesicle transport in chloroplasts with emphasis on Rab proteins

... major life-forms on earth, because of the photosynthesis reaction that occurs in photosynthetic ...Calvin cycle is hosted in the stroma and fixes carbon dioxide into stable ...associated proteins and ...

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Rab proteins specify motorized vesicle transport.

Rab proteins specify motorized vesicle transport.

... Rab5 effector hVPS34/P150, a phospha- tidylinositol-3-OH kinase (Hoepfner et ...numerous interactions of Rab proteins with the cytoskeleton an overview is given in table ...

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Intrinsic tethering activity of endosomal Rab proteins.

Intrinsic tethering activity of endosomal Rab proteins.

... classical Rab-effector mechanisms to promote membrane tethering, docking, and fusion ...of Rab-Rab ...These interactions are consistent with our results for yeast endocytic Rabs, ...

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Viral and host proteins involved in picornavirus life cycle

Viral and host proteins involved in picornavirus life cycle

... These interactions, however, do not cause viral instability or uncoating, but probably result in the aggregation of other receptors, or trigger the subsequent ...capsid proteins with intracellular host ...

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ISG15 Functions as an Interferon-Mediated Antiviral Effector Early in the Murine Norovirus Life Cycle

ISG15 Functions as an Interferon-Mediated Antiviral Effector Early in the Murine Norovirus Life Cycle

... These proteins are also important for tethering the actin cytoskel- eton near endosomal membranes undergoing vesicular trafficking ...annexin interactions with lipids rafts or binding to actin filaments and ...

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Genetic Analysis of Yeast Yip1p Function Reveals a Requirement for Golgi-Localized Rab Proteins and Rab-Guanine Nucleotide Dissociation Inhibitor

Genetic Analysis of Yeast Yip1p Function Reveals a Requirement for Golgi-Localized Rab Proteins and Rab-Guanine Nucleotide Dissociation Inhibitor

... critical proteins in a manner dependent on COOH-terminal players in a variety of fundamental cellular pro- prenylation (Calero et ...with Rab-GDI for Rab protein interactions in ...to ...

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A New Method To Determine In Vivo Interactomes Reveals Binding of the Legionella pneumophila Effector PieE to Multiple Rab GTPases

A New Method To Determine In Vivo Interactomes Reveals Binding of the Legionella pneumophila Effector PieE to Multiple Rab GTPases

... 300 effector proteins into host ...missed interactions, as they are not performed in the context of an infec- ...the effector PieE and describe a new method to identify host cell targets un- ...

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Isolation and functional characterization of

Arabidopsis powdery mildew effector proteins

Isolation and functional characterization of Arabidopsis powdery mildew effector proteins

... on effector expression in ...the effector expression in waves that has been detected in other ...the life cycle could reveal host processes specifically target to meet the increased metabolic ...

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Microtubule plus end binding proteins and nuclear movements in the Saccharomyces cerevisiae life cycle

Microtubule plus end binding proteins and nuclear movements in the Saccharomyces cerevisiae life cycle

... bud results in activation of mitotic exit, Tem1p-Lte1p interactions either have to occur in the cytoplasm or Tem1p interacts with Lte1p at the bud cortex and then re-localizes to the dSPB. Because there is no ...

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Interactions of Claspin with replication and checkpoint proteins

Interactions of Claspin with replication and checkpoint proteins

... cell cycle. Several classes of proteins have been identified and are summarized ...Sensor proteins can be regrouped according to their biochemical ...Mediator proteins are also classified ...

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Thirty-One Flavors of Drosophila Rab Proteins

Thirty-One Flavors of Drosophila Rab Proteins

... Rab proteins are small GTPases that play important roles in transport of vesicle cargo and recruitment, association of motor and other proteins with vesicles, and docking and fusion of vesicles at ...

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Interactions between the Powdery Mildew Effector BEC1054 and Barley Proteins Identify Candidate Host Targets

Interactions between the Powdery Mildew Effector BEC1054 and Barley Proteins Identify Candidate Host Targets

... ffector interactions to discover plant proteins that are involved in host ...Arabidopsis proteins and e ffectors from the bacterium Pseudomonas syringae, from the oomycete Hyaloperonospora ...

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The life cycle of submesoscale eddies generated by topographic interactions

The life cycle of submesoscale eddies generated by topographic interactions

... Revised: 13 September 2019 – Accepted: 10 October 2019 – Published: 22 November 2019 Abstract. Persian Gulf Water and Red Sea Water are salty and dense waters flowing at intermediate depths in the Gulf of Oman and the ...

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Cooperation of structural proteins during late events in the life cycle of polyomavirus.

Cooperation of structural proteins during late events in the life cycle of polyomavirus.

... The 2D gel analysis of VP1 protein species synthesized in insect cells in the presence or absence of the minor proteins has revealed a possible function for the VP2 antigen in mediating [r] ...

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Endogenously Tagged Rab Proteins: A Resource to Study Membrane Trafficking in Drosophila

Endogenously Tagged Rab Proteins: A Resource to Study Membrane Trafficking in Drosophila

... Wang and Struhl, 2004). It will be interesting to further investigate how Rab35 and Rab23 influence signal transduction. DISCUSSION Here, we describe a genetic resource for visualization of endog- enous Rab ...

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Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis

Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis

... As Rab proteins are members of the larger Ras protein family we needed to also address the problem of randomly identifying non-Rab sequences with the ...using Rab sequences, non-Rab ...

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Computational Prediction of Effector Proteins in Fungi: Opportunities and Challenges

Computational Prediction of Effector Proteins in Fungi: Opportunities and Challenges

... Canada Effector proteins are mostly secretory proteins that stimulate plant infection by manipulating the host ...fungal effector proteins and understanding their function is of great ...

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