Radiation sensitivity
Nimotuzumab enhances radiation sensitivity of NSCLC H292 cells in vitro by blocking epidermal growth factor receptor nuclear translocation and inhibiting radiation-induced DNA damage repair
... ionizing radiation. The radiation sensitivity enhancement ratio (SER) was ...and radiation) increased both in the cytoplasm and the nucleus along with the decreased expression of nuclear ...
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Methyl jasmonate enhances the radiation sensitivity of esophageal carcinoma cells by inhibiting the 11-ketoprostaglandin reductase activity of <em>AKR1C3</em>
... Notes: (A) KY170R cells incubated with different densities (0,100, and 200 μmol/l) of MeJ for 24 h. expression levels of PPaRγ in KY170R cells were detected by Western blot analysis. MeJ could activate the PPaRγ ...
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Silencing of insulin like growth factor 1 receptor enhances the radiation sensitivity of human esophageal squamous cell carcinoma in vitro and in vivo
... Thus, new therapeutic methods are urgently needed for the improvement of ESCC clinical treatment. It has been demonstrated that some pathogenic factors, such as cancer-related genes, are related to the progression and ...
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THE GENETIC BASIS FOR MUCOIDY AND RADIATION SENSITIVITY IN capR (lon) MUTANTS OF E. coli K-12
... EfJects of polarity suppressors on overproduction of polysaccharide: The possi- bility that capR mutations lie in a cistron related to radiation sensitivity and that overproduc[r] ...
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Antigen induced human T cell help Precursor frequency, radiation sensitivity, and allogeneic effects
... present study, these differences were analyzed in terms of the precursor frequencies for the T cells and B cells involved and in terms of the radiation sensitivity of the T cells providing help in the two ...
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miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition
... crease radiation sensitivity of human PCa xenografts through down-regulation of multiple DNA repair genes [14, ...the radiation response of both in vitro and in vivo PCa experimental models by ...
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A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose
... a radiation-independent effect on survival that renders interpretation of their impact on the low dose region of the survival curve ...(1) radiation-independent survival (parameter z, Equation 1), (2) ...
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Validation of the cell cycle G<sub>2</sub> delay assay in assessing ionizing radiation sensitivity and breast cancer risk
... point and repair pathways to correct DNA damages prior to replication may result in the propagation of deleterious chro- mosomal aberrations and mutations that decrease genomic stability and lead to transformation. ...
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Original Article CK2 inhibitor CX4945 enhances the radiation sensitivity of human gastric cancer cells
... Cisplatin is one of the most potent chemothera- peutics widely used in cancer chemotherapy. The anti-cancer mechanism of cisplatin is attributed to the platinum-DNA adducts induced DNA double strand breaks. Cisplatin ...
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Oleuropein enhances radiation sensitivity of nasopharyngeal carcinoma by downregulating PDRG1 through HIF1α-repressed microRNA-519d
... P53 and PDRG1 have been reported to be upregulated in multiple cancers including lung, breast, stomach, colon, rectum and ovary cancers [22]. PDRG1 expression was found to be correlated with higher or more ad- vanced ...
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GENETIC CONTROL OF RADIATION SENSITIVITY IN SACCHAROMYCES CEREVISIAE
... Other mutants (4/10) identified by these authors were also X-ray sensitive, while none of the UV-sensitive mutants identified by SNOW (1968) were recombination- deficient.. T[r] ...
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THE ROLE OF RECOVERY MECHANISMS AND OXYGEN EFFECTS UPON CHANGES IN RADIATION SENSITIVITY IN SPERM TREATED IN MATURE MALES AND FERTILIZED FEMALES OF DROSOPHILA
... With X-ray treatment in nitrogen, there is a similar increase in translocations and sex-linked lethals of 2.94 percent and 2.71 percent in sperm treated in inseminated females [r] ...
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Radiation sensitivity tests of the HARMONIE 37h1 NWP model
... the radiation calculations: in- correct cloudiness (liquid or ice water loads and their dis- tributions) or poorly known properties of the clouds (size and shape of the cloud particles), which influence the SW ...
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X-Ray Survival Characteristics and Genetic Analysis for Nine Saccharomyces Deletion Mutants That Show Altered Radiation Sensitivity
... deletions3.html. The prototrophic wild-type strains X2180-1A to unirradiated controls (Game et al. 2003). However, and X2180-1B were available to us from R. K. Mortimer. They ⵑ9% of deletion mutants in this ranking were ...
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A LOCUS FOR RADIATION SENSITIVITY IN ESCHERICHIA COLI B s-2
... When strain K-I2 was used as a donor in crosses with strain B, radiation resistance was transferred to the recombinants, the gene responsible for radiation resistance[r] ...
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Raltitrexed increases radiation sensitivity of esophageal squamous carcinoma cells
... in radiation induced signal trans‑ duction including Bax, Cyclin B1, Cdc2/pCdc2, and Cdc25C/pCdc25C were examined by western blot ...of radiation in nude ...
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Radiation sensitivity tests of the HARMONIE 37h1 NWP model
... various radiation parameterisations, avail- able in the HARMONIE NWP model, against the accurate one-dimensional radiative transfer model, DISORT (Stamnes et ...the radiation schemes available in HAR- MONIE ...
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Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model
... for 3 hours, the cells were harvested to examine apop- tosis using Cell Death Detection ELISA Plus kit according manufacturer’s instructions. Apoptosis was not signifi- cantly induced in cells treated with either ...
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LOCI FOR RADIATION SENSITIVITY IN ESCHERICHIA COLI STRAIN Bs1
... Further confirmation that UV sensitivity of Bs-l resulted from each of two mutations was obtained from the following crosses: HfrH x PAM 12 selecting Lac+ Str recomb[r] ...
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Distorted Reflector Antennas: Radiation Pattern Sensitivity to the Surface Distortions
... “radiation sensitivity to reflector surface” for reflector antennas was ...as sensitivity contours as they can show the regions with stronger effects on far-field ...the sensitivity of co- and ...
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