Randomized Placebo-Controlled Study
A pilot double-blind, randomized, placebo-controlled trial of the efficacy of trace elements in the treatment of endometriosis-related pain: study design and methodology
... double-blind, randomized, placebo-controlled study aiming to evaluate the efficacy of metal trace elements on the reduction of pain and improvement of quality of life, in patients with a ...
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Advances in targeted and immunobased therapies for colorectal cancer in the genomic era
... Phase III randomized, placebo- controlled study of cetuximab plus brivanib alaninate versus cetuximab plus placebo in patients with metastatic, chemotherapy-refractory, wild- type K-RAS[r] ...
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Development of oral agent in the treatment of multiple sclerosis: how the first available oral therapy, Fingolimod will change therapeutic paradigm approach
... IIb study. The second study was a Phase IIb, multinational, randomized, double-blind, parallel-group, placebo-controlled 36-week study, evaluating the efficacy, tolerability, and ...
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Long-term safety, efficacy, and tolerability of imidafenacin in the treatment of overactive bladder: a review of the Japanese literature
... a randomized, double-blind, placebo-controlled Phase II study and a propiverine-controlled Phase III study conducted in Japanese patients demonstrated that imidafenacin ...not ...
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Lamotrigine Adjunctive Therapy Among Children and Adolescents With Primary Generalized Tonic-Clonic Seizures
... published randomized clinical trials for childhood partial seizures, absence sei- zures, and for the generalized seizures associated with Lennox-Gastaut ...A randomized, blinded, ...
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Does different information disclosure on placebo control affect blinding and trial outcomes? A case study of participant information leaflets of randomized placebo-controlled trials of acupuncture
... of placebo acu- puncture: “full disclosure of placebo acupuncture (FD)”, “deceptive disclosure of placebo acupuncture (DD)”, and “missing information on placebo acupuncture ...the study ...
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Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): protocol for a prospective randomized controlled trial
... Another study found no significant decrease in the incidence of postoperative delirium with the use of dexme- detomidine but was likely underpowered ...recent study compared postoperative sedation using ...
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Scopolaminebutyl given prophylactically for death rattle: study protocol of a randomized double-blind placebo-controlled trial in a frail patient population (the SILENCE study)
... In line with this, we appointed a local researcher from the local professional care teams. Although it is common in clinical trials in hospitals that health care profes- sionals (e.g. medical doctors and nurse ...
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Duloxetine versus placebo for the treatment of women with stress predominant urinary incontinence in Taiwan: a double-blind, randomized, placebo-controlled trial
... blind, randomized, parallel, placebo-controlled, clinical trial conducted at 9 study centers in ...and study design was reviewed by a local ethics committee in accordance with the ...
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Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS): study protocol for a randomized placebo controlled trial in Ugandan children with sickle cell anemia
... the study will have scheduled clinic visits at 1, 3, 6, 9, and 12 months to assess study adherence by pill counts, evaluate AEs, assess weight and height, and to refill zinc or placebo tablet ...and ...
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A meta-analysis of the placebo response in antimuscarinic drug trials for overactive bladder
... the study was a double- blind randomized placebo-controlled trial of an antimus- carinic medication in patients with OAB; 2) the total number of patients assigned to placebo was ...
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Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects
... This study utilized two dosage levels of GCA, as well as a ...The placebo condition consisted of a 350 mg inert capsule of an inactive substance taken orally three times ...
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Potential of ramucirumab in treating hepatocellular carcinoma patients with elevated baseline alpha-fetoprotein
... designed randomized 2:1, double-blind, placebo- controlled phase III study, REACH-2, which enrolled 292 Child-Pugh score A score, performance status 0–1 patients with elevated AFP levels at ...
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Rizatriptan in migraineurs with unilateral cranial autonomic symptoms: a double-blind trial
... this randomized, double-blind, placebo-controlled, parallel-group, outpatient study to assess the efficacy of rizatriptan 10 mg wafer in treating a single acute migraine attack in migraineurs ...
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Randomized, placebo-controlled, double-blind study assessing the efficacy and safety of paliperidone palmitate in Asian patients with schizophrenia
... this study compared with the studies reported ...current study being clinically more stable, as noted by their slightly longer dura- tion of illness ...
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Everolimus in the treatment of subependymal giant cell astrocytomas, angiomyolipomas, and pulmonary and skin lesions associated with tuberous sclerosis complex
... III, randomized, double-blind, placebo-controlled—A Randomized, Double-blind, Pla- cebo-controlled Study of RAD0001 in the Treatment of Angiomyolipoma in Patients With Either ...
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Design and rationale of a randomized controlled trial of melatonin supplementation in men and women with the metabolic syndrome
... Analysis of primary endpoints was performed according to the intent-to-treat principle. Standard statistical methods for a one-period crossover design were employed using Statistical Analysis Software (SAS Inc, Cary, NC, ...
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Repetitive H Wave® device stimulation and program induces significant increases in the range of motion of post operative rotator cuff reconstruction in a double blinded randomized placebo controlled human study
... their study that Arthroscopic repair of medium and large full - thickness rotator cuff tears had an equal outcome to technically unsuccessful arthroscopic repairs, which were salvaged by conversion to a mini -open ...
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Randomized, double-blind, placebo-controlled and active-controlled study to assess the relative abuse potential of oxycodone HCl-niacin tablets compared with oxycodone alone in nondependent, recreational opioid users
... The adverse events experienced by study participants taking oxycodone were typical of opioid use. Nausea, vomit- ing, pruritus, somnolence, and decreased oxygen saturation of hemoglobin generally showed a ...
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Randomized, Placebo Controlled Trial of Transdermal Rivastigmine for the Treatment of Encephalopathy in Liver Cirrhosis (TREC Trial)
... Patients were eligible if they had grade 2 or 3 HE. Hepatic encephalopathy grades were based on clinical and electroencephalographic criteria [19] [20]. Grade 2 HE was characterized by the presence of lethargy, inappro- ...
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