rat aortic smooth muscle
Retinoic acid uses divergent mechanisms to activate or suppress mitogenesis in rat aortic smooth muscle cells
... In different experimental models, retinoid has been shown to stimulate or suppress mitogenesis in cultured cells. The mechanisms underlying this seemingly paradoxical activity remain only partially understood. We have ...
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Abundant expression of parathyroid hormone related protein in primary rat aortic smooth muscle cells accompanies serum induced proliferation
... hypercalcemia in patients with humoral hypercalcemia of malignancy, has recently been identified in several normal tissues. Because PTHrP, like parathyroid hormone (PTH), is known to exhibit vasodilatory properties, we ...
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Stimulation of activin A expression in rat aortic smooth muscle cells by thrombin and angiotensin II correlates with neointimal formation in vivo
... vascular smooth mus- cle ...-thrombin–stimulated rat aortic smooth muscle (RASM) cells, neutralizing antibodies directed against sev- eral growth factors ...a rat carotid in- ...
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Repair of protease damaged elastin in neonatal rat aortic smooth muscle cell cultures
... The objective of this study was to investigate the elastin repair process in the rat aortic smooth muscle cell culture after proteolytic injury. Although little studied in vivo, elastin repair ...
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C Jun NH2 Terminal Kinase Contributes to Dexmedetomidine Induced Contraction in Isolated Rat Aortic Smooth Muscle
... 19. Sung HJ, Sohn JT, Park JY, Hwang EM, Baik JS, Ogawa K. Di- rect effect of ropivacaine involves lipoxygenase pathway activa- tion in rat aortic smooth muscle. Can J Anaesth 2009;56:298-306. ...
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Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor
... of smooth muscle cell (SMC) proliferation that contributes to post angioplasty ...cultured rat aortic SMC, stimulating an increase in 3H-thymidine incorporation, as well as an increase in cell ...
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Rat aortic smooth muscle cells in culture express kallikrein, kininogen, and bradykininase activity
... studied rat vascular smooth muscle (VSM) cells in culture for the presence of key elements of the glandular kallikrein-kinin ...against rat urinary kallikrein detected a glandular ...
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Epidermal growth factor, a vascular smooth muscle mitogen, induces rat aortic contraction
... vascular smooth muscle proliferation is a prominent feature of atherosclerosis, we postulated that vasoactive agonists and smooth muscle mitogens may share certain common cellular mechanisms ...
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Sustained inhibition of intimal thickening In vitro and in vivo effects of polymeric beta cyclodextrin sulfate
... of rat aortic smooth muscle cells with an insoluble, sulfated polymer of beta-cyclodextrin (P-CDS) was associated with a dose-dependent inhibition of proliferation induced by fetal calf serum, ...
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VEGF B inhibits apoptosis via VEGFR 1–mediated suppression of the expression of BH3 only protein genes in mice and rats
... primary aortic smooth muscle cells, and confirming the results by real- time PCR using mouse and rat cell lines, we showed that VEGF-B inhibited the expression of genes encoding the ...
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Protective Role for Properdin in Progression of Experimental Murine Atherosclerosis
... anti-human smooth muscle actin (SMA, Dako M0851, 1:150, 1 h), purified anti-mouse CD206 (Biolegend 123001, rat IgG2ak, 1:100, 1 h RT), (trypsination for antigen retrieval: ...
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Original Article Tobacco smoke induces MMP-2 activation in rat aortic vascular smooth muscle cells via Egr1
... Smoking is an independent risk factor for ath- erosclerosis (As) [1]. However, the mechanisms of As caused by smoking remain unclear. MMP-2 plays an important role in migration, proliferation, and vascular remodeling of ...
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Adenosine relaxation in isolated rat aortic rings and possible roles of smooth muscle Kv channels, KATP channels and A2a receptors.
... sine relaxation, implicating endothelial relaxation factors such as NO for relaxation [42]. These contrasting results may be due to differences in species, age, prior disease state, aortic ring preparation, ...
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Actin expression in smooth muscle cells of rat aortic intimal thickening, human atheromatous plaque, and cultured rat aortic media
... of smooth muscle cells of rat and human aortic media shows a predominance of the ...experimental rat aortic intimal thickening, in human atheromatous plaque, and in cultured ...
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Effects of cyclic stretch on the molecular regulation of myocardin in rat aortic vascular smooth muscle cells
... on rat carotid ar- tery VSMCs following vascular injury have demonstrated that myocardin can selectively regulate SRF binding to the degenerate CArGs on VSMC actin to increase transcrip- tional ...
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Cytomegalovirus infection enhances smooth muscle cell proliferation and intimal thickening of rat aortic allografts
... Inbred DA (AG-B4, RT1a) and WF (AG-B2, RT1v) rats were used as donors and recipients of aortic allografts. The recipient rats were inoculated i.p. either on day 1 (early infection) or on day 60 (late infection) ...
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Original Article Chinese rice wine polyphenol compounds inhibit vascular smooth muscle cell dedifferentiation and its mechanism
... inhibit rat aortic vascular smooth muscle cells (VSMCs) dedifferentiation through mammalian target of rapamycin (mTOR)/P70S6K ...of rat VSMCs was conducted and VSMCs in passages 3-5 ...
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Adenosine and lidocaine (AL) as a vasodilator in cardiac procedures and a storage solution for vascular banking
... in rat aortic rings at low lidocaine concentrations, and 2) a strong endothelial dependence which enhanced relaxation after its removal (Figure ...in rat cremaster skeletal muscle (Johns, et ...
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The effects of modified low density lipoprotein on coronary artery endothelial and smooth muscle cells
... renal) expiants. In addition, left internal mammary arteries deemed unsuitable for coronary bypass grafting may be used as a further source of arterial endothelial cells. The isolation and culture of microvessel ...
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Somite derived cells replace ventral aortic hemangioblasts and provide aortic smooth muscle cells of the trunk
... of smooth muscle cells This origin had been proposed some years ago (Brand-Saberi and Christ, 2000) but has never been demonstrated ...generate smooth muscle cells (DeRuiter et ...the ...
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