rat cortical neurons
Humanin rescues cultured rat cortical neurons from NMDA-induced toxicity through the alleviation of mitochondrial dysfunction
... rescue rat cortical ...the neurons through the attenuation of mitochondrial ...cultured rat cortical ...the neurons with HN (1 μmol/L) led to significant increases of ...
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EFFECTS OF RHYNCHOPHYLLINE ON RAT CORTICAL NEURONS STRESSED BY METHAMPHETAMINE
... on cortical neurons in rats and to study the protective effects of Rhynchophylline (Rhy) on MA treated ...cultured cortical neurons. The viability of neurons treated MA for 48 h ...
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Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA
... apoptosis, neurons activate robust DNA repair ...which neurons tolerate DNA damage accumulation as well as defining the genomic regions that are more vulnerable to DNA damage or refractory to DNA repair and ...
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<p>Thymosin β4 prevents oxygen-glucose deprivation/reperfusion-induced injury in rat cortical neurons</p>
... Primary rat cortical neurons were transfected with T β 4 overexpression plasmid; the transfection ef fi ciency was con fi rmed by detecting T β 4 expression by fl uorescence quantitative PCR and Western ...
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Mercury-induced toxicity of rat cortical neurons is mediated through N-methyl-D-Aspartate receptors
... the concentrations of 25 nM, 100 nM, and 25 μM for 3 days. Neuronal viability, neurite outgrowth and net- work formation were evaluated 3 days later. The choices of these experimental doses were based on the studies ...
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Diversity of intrinsic frequency encoding patterns in rat cortical neurons : mechanisms and possible functions
... of neurons connected with each other in a network can perform much better than a single ...that neurons in the network are identical, receive the same input, and are connected with each other by excitatory ...
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Naked mole-rat cortical neurons are resistant to acid-induced cell death
... sensory neurons demonstrated an increased frequency and magnitude of ASIC responses in NMR neurons compared to mouse neurons [43], with APETx2, an inhibitor of ASIC3-containing ASICs, demon- strating ...
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Activity-Dependent A-to-I RNA Editing in Rat Cortical Neurons
... Figure 3 Activity-dependent changes in RNA editing at 6 and 48 hr. (A) Editing levels (fraction inosine) for High Na 6 hr (control) and High K 6 hr (depolarizing) treatments at each editing site. Asterisks indicate ...
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Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons
... vulnerable neurons of the Alzheimer’s disease (AD) brain and transgenic mouse models of AD; these proteins are associated with various paradigms of neuronal ...developing rat brain, and that gene is one of ...
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Intermittent Hypothermia Is Neuroprotective in an in vitro Model of Ischemic Stroke
... Fetal rat cortical neurons isolated from Day E18 rat embryos were subjected to 90-min OGD and hypothermia treatments during reoxygenation before examining the changes in mi- croscopic ...
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Original Article Brain-derived neurotrophic factor protects rat cerebral cortical neurons from intermittent hypoxia in vitro
... embryonic rat cortical neurons exposed to intermittent hypoxia involved CREB ...encoding rat BDNF (Ad-BDNF) and performed an enzyme linked immunosor- bent assay (ELISA) to measure the levels ...
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Extracellular cathepsin L stimulates axonal growth in neurons
... [8], while cathepsin B-null mice did not have an obvious phenotype [9]. This could be attributed to a compensa- tion for each other due to overlapping substrate specific- ity. Double knockout mice of cathepsin L and ...
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Laminar degeneration of frontal and temporal cortex in Parkinson disease dementia
... In all gyri and cases (Table 2), in 26/39 (67%) gyri there were no significant changes in density of LB across the cortex. However, LB were distributed in lower laminae in 10/39 (26%) gyri, while in further three gyri, ...
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Transplacental thyroxine and fetal brain development
... that cortical neurons occupying different lamina are born at different ...Specifically, neurons born late in the process of cortical development migrate past cells born earlier to occupy more ...
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Loss of GABAergic cortical neurons underlies the neuropathology of Lafora disease
... GABAergic cortical neurons is reduced in Laforin-deficient mice, which again underlie a possible specific role of GABAergic neurons in the development of the ...of cortical neurons are ...
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Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons
... of cortical layer V (Hevner et ...for cortical cells committed to a deep layer ...of cortical development, around E12-E13 (Takahashi et ...ER81-positive neurons are positioned in the inner ...
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Apoptosis plays an important role in experimental rabies virus infection.
... Rat prostatic adenocarcinoma cells transfected with pZipNeo (AT3) and with pZip-bcl-2/neo containing the human bcl-2 open reading frame (AT3-Bcl-2), which were obtained from Diane Griffin (Johns Hopkins ...
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Astrocytes, neurons, synapses: a tripartite view on cortical circuit development
... and neurons is important for synapse formation, as neurons cultured from E17 rat embryos, a time before astrocytes are generated, do not form synapses in response to astrocyte-secreted signals, while ...
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Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles
... Our results showed that physicochemically character- ized DPP80 niosomes elaborated with a mixture of both P and P80 nonionic surfactants were able to transfect efficiently NT2 cells without compromising their viabil- ...
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Adenosine A2B receptor-mediated leukemia inhibitory factor release from astrocytes protects cortical neurons against excitotoxicity
... mouse cortical neurons against excitotoxicity ...the neurons (for 24 hours before application of glutamate) with NECA (1 μM) or supernatant from untreated astrocytes did not affect glutamate-induced ...
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