Rat glomerular mesangial cells
Prostaglandin synthesis by rat glomerular mesangial cells in culture Effects of angiotensin II and arginine vasopressin
... the glomerular filtration rate and ultrafiltration ...cause mesangial cell ...cultured rat glomerular mesangial ...passage. Mesangial cell morphology was confirmed by electron ...
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Low density lipoprotein enhances the cellular action of arginine vasopressin in rat glomerular mesangial cells in culture
... in rat glomerular mesangial cells in ...When cells were preincubated for 24 h with 10 microgram/ml LDL, the 1 x 10(-7) M AVP- mobilized [Ca2+]i was 874 nM, a value significantly greater ...
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Original Article Mitofusin 2 expression in IgA1 induced rat glomerular mesangial cells and IgA nephrology animal model
... induced rat glomerular mesangial cells, while overexpressed Mfn2 could alleviate glomerular mesangial cell (GMC) proliferation and increase apoptosis, and that Mfn2 may exert its ...
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Effects of Dangguibuxue decoction on rat glomerular mesangial cells cultured under high glucose conditions
... The membranes were washed three times and the immunoreactive proteins were detected by enhanced chemiluminescence (ECL kit, purchased from GE Health- care LifeSciences, Piscataway, NJ) on radiographic films (purchased ...
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Rat glomerular mesangial cells synthesize basic fibroblast growth factor Release, upregulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis
... various glomerular diseases in ...potent mesangial cell mitogen in ...in rat mesangial cell (RMC) proliferation, we examined whether RMC synthesize bFGF in vitro and whether bFGF is involved ...
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Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor beta expression in rat glomerular mesangial cells
... of rat mesangial cells in culture increased TGF-beta and matrix components biglycan, fibronectin, and collagen type I at both the mRNA and protein levels in a time- and dose-dependent ...of ...
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Endothelin 1 stimulates contraction of rat glomerular mesangial cells and potentiates beta adrenergic mediated cyclic adenosine monophosphate accumulation
... dimensional gels of collagen type I. ET-1 also caused complex rearrangements of F-actin microfilaments consistent with a motile response. Contraction in response to ET-1 occurred only at concentrations that activate ...
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Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells
... trix metalloproteinase 2 (MMP-2) (28), 0.6 kb EcoRI fragment of hu- man tissue inhibitor of metalloproteinase 2 (TIMP-2), 3.9 kb the XbaI fragment of pTZ for human TIMP-1 (29), and 2.0 kb EcoRI fragment of hTGF b -2 for ...
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Naringin ameliorates the high glucose induced rat mesangial cell inflammatory reaction by modulating the NLRP3 Inflammasome
... of rat glomerular mesangial cells at different time points To investigate the effect of high glucose concentrations on rat glomerular mesangial cells over time, we ...
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Lovastatin inhibits proliferation of rat mesangial cells
... reduced mesangial cellularity and glomerular injury in experimental renal ...in rat glomerular mesangial ...arrested mesangial cells were exposed to medium containing 10% ...
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Microscopical observation of kidney for ameliorative effects of Vitamin - E & C in streptozotocin-induced diabetic rats
... the glomerular capillaries, increased mesangial cells and distinct mesangium, shortened podocyte processes and disappearance of filtration slit pore of diabetic rat kidney were ...VEC, ...
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Cytokine stimulated secretion of group II phospholipase A2 by rat mesangial cells Its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cells
... mesangial cells. In all cases 85-90% of the enzyme is secreted from the cells and a parallel increase in prostaglandin (PG)E2 synthesis is ...neutralizes rat group II PLA2 attenuates IL-1 beta ...
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Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney Elucidation of signal transduction pathways
... The glomerular ultrafiltration coefficient (Kf) fell from ...to mesangial cells plated on a silicone rubber substrate increased the intensity and number of tension-generated wrinkles, and caused ...
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Intraglomerular pressure and mesangial stretching stimulate extracellular matrix formation in the rat
... of glomerular hypertension and hypertrophy with mesangial extracellular matrix (ECM) deposition, we examined the effects of glomerular capillary distention and mesangial cell stretching on ECM ...
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Effects of Carpio Decoction on the Structure of Kidney in Rats with Adriamycin Induced Nephrosis
... in rat kidneys were respectively detected by HE stain and im- munohistochemiscal ...Renal glomerular capillaries congestive of group M rats were ...expansion. Glomerular mesangial cells ...
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Transforming growth factor beta Murine glomerular receptors and responses of isolated glomerular cells
... resident glomerular cells and the accumulation of mesangial matrix are histologic abnormalities which are observed in the course of many progressive glomerular ...mouse glomerular ...
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Production of platelet derived growth factorlike protein by rat mesangial cells in culture
... Rat mesangial cells (MC) release a factor that competes in a dose-dependent manner with 125I-labeled platelet-derived growth factor (PDGF) for binding to human foreskin fibroblasts ...in ...
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induced fibronectin production in rat mesangial cells
... in glomerular mesangium correlates with loss of renal func- tion in diabetic ...in rat mesangial cells (MCs) stimulated by high glucose or transforming growth factor-β 1 (TGF-β 1 ), and ...
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Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis Alpha smooth muscle actin is a marker of mesangial cell proliferation
... whether mesangial of mesangial proliferative nephritis induced with antibody to the Thy-1 antigen present on mesangial ...a mesangial pattern, correlating with the onset of proliferation, and ...
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Physiologic regulation of atrial natriuretic peptide receptors in rat renal glomeruli
... normal rat glomeruli. Analogues of ANP that bound to the glomerular ANP receptor with high affinity stimulated cGMP accumulation, whereas the (13-28) ANP fragment, which failed to bind to the receptor, was ...
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