rat hippocampal brain slices
Original Article Dexmedetomidine inhibits epileptiform activity in rat hippocampal slices
... immersed, slices were cut with a vibrating tissue slicer (DTK-3000; Dosaka EM, Kyoto, ...The brain slices, each 350 μm thick, were immedi- ately transferred to a holding chamber filled with normal ...
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Original Article Paeoniflorin down-regulates the expression of NLRP1 and NLRP3 inflammasomes in rat hippocampal slices after oxygen-glucose deprivation
... emic brain tissue, we slightly modified the pro- tocols of organotypic hippocampal slice culture (OHSC), which were successfully developed [16] to obtain hippocampal slices, and exposed the ...
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Non-associative hippocampal long-term depression (LTD) and associative neocortal long-term potentation of synaptic transmission in rat brain slices
... the slices with acsf containing 25 mM Mg^"^ and 2 mM ...of slices to 25 mM Mg^"^ 2 Ca^^ resulted in block of both orthodromic and antidromic responses at all depths within the slice in 2 to 5 ...
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Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr 1 in rat hippocampal slices
... in hippocampal brain slices following exposure to ...developing brain to drugs that block NMDA glutamate receptors or drugs that potentiate GABA(A) receptors can induce apoptotic ...
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PubMedCentral-PMC4844565.pdf
... the brain is not known ...in rat and mouse hippocampal slices using intrinsic optical signal (IOS) recording, in which we measured relative changes in intracellular and extracellular volume as ...
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Interactive Effects of Exercise, Sex Hormones, and Transient Congenital Hypothyroidism on Long-Term Potentiation in Hippocampal Slices of Rat Offspring
... Transverse slices (450 μm) were prepared with a Vi- broslice (Campden Instruments, Silbey, ...The slices were stored in a brain slice keeper oxygenated with 95% O 2 /5% CO 2 at room temperature for ...
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Some Biochemical Changes of Rat Hippocampal Slices under the Long term Creatine Intraperitoneal Supplementation
... Aggressive and non-aggressive rats also differ by some biochemical parameters, such nitric oxide (NO) among others. It is an important mediator closely involved in various metabolic processes within the cell. Recent ...
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beta Hydroxybutyrate fuels synaptic function during development Histological and physiological evidence in rat hippocampal slices
... D - b HB. This strongly suggests that the change in energy utili- zation produced by IA is not identical to glucose deprivation. We initially speculated that the presence of glucose, even dur- ing glycolytic inhibition, ...
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A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices
... the brain macrophages, ...the brain has been studied extensively [7-11], most progress on the understanding of the role of microglia in inflammation has come from cell culture and slice culture ...
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Nervous System and Gastrointestinal Effects of the Insecticide Esfenvalerate on the Rat: An Ex Vivo Study
... and hippocampal brain slices, while gastrointestinal effects were examined by analyzing the motility and excitabili- ty of isolated ileum ...the brain slices originating from ...
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Intracellular ATP influences synaptic plasticity in area CA1 of rat hippocampus via metabolism to adenosine and activity dependent activation of adenosine A1 receptors
... combined hippocampal/neocortical slices at ...between hippocampal and cortical tissue, unpaired t ...in hippocampal tissue ( ⬃ 10 nmol/mg protein, ⬃29%), which additionally requires more ...
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Involvement of cellular metabolism in age-related LTP modifications in rat hippocampal slices
... The hippocampal slices of each rat were divided into ten experimental groups (Table ...where hippocampal slices were fixed after brain preparation, without any exogenous ...
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GABA-mediated inhibitory postsynaptic currents recorded in rat hippocampal slices using intracellular and patch clamp recording techniques
... in brain slices allowed the study of hippocampal IPSCs to be contin ued with a much higher ...from hippocampal CA1 cells of adult (more than three month old) rats, while the patch clamp ...
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The Sources of Extracellular Adenosine in Hippocampus and Neostriatum of the Rat Brain
... We have determined the effect of ectonucleotidase and adenosine kinase on field potentials from hippocampal and neostriatal slices, in order to esti- mate the relative contributions of [r] ...
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β-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices
... Unsectioned slices were immunostained for the microglial marker F4/80. Slices were fixed with 4% paraf- ormaldehyde in PBS for 10 mins and then stored at 4°C in PBS until ...rinsing, slices were ...
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Targeting the purine salvage pathway in in vitro models of cerebral ischemia
... Due to the high activities of ATPases in fresh samples, changes in the adenine nucleotide levels take place very quickly when ATPase enzymes are not inactivated immediately. Snap-freezing of tissues in liquid nitrogen is ...
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Bwlding the Molecular Machinery of Memory: Local Protein Synthesis in Hippocampal Neurons
... Using radiolabeling, Feig and Lipton 1993 showed that newly synthesized proteins could be detected in dendrites of hippocampal slices-the timing was such that the cell body was unlikely [r] ...
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Transient extracellular application of gold nanostars increases hippocampal neuronal activity
... results in star shapes of 180 nm in average width and 70% yield (Figure 1). Energy dispersive X-Ray spectroscopy (EDS) analysis confirms that the nanoparticles are made out of gold (Figure 2). As described in Methods we ...
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Original Article Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model
... of hippocampal cells; the presence of irregular, uneven and unclear nuclear membranes, with local ruptures; swell- ing/degeneration of mitochondria in the cyto- plasm and disappearance of the crests; mild dilation ...
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The Nedd4-binding protein 3 (N4BP3) is crucial for axonal and dendritic branching in developing neurons
... [31]. The resulting phenotype, a loss of predominantly secondary and tertiary branches and a significantly de- creased ACI, does in fact resemble the Nedd4-KD phenotype in axons [15,18]. Because Nedd4 is crucial not only ...
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