real-world patients' clinical data
Developing a multi-center clinical data mart of ACEI and ARB for real-world evidence (RWE)
... The data mart built in this study includes data on all patients who were first prescribed ...of data, except for that described in the Methods ...missing data for each item (because of ...
7
<p>Modified FOLFIRINOX for unresectable locally advanced/metastatic pancreatic cancer. A real-world comparison of an attenuated with a full dose in a single center experience</p>
... the patients treated at our institution receiving an attenuated dose of FOLFIRINOX, our fi ndings suggest that the ef fi cacy was not compromised by this reduction, with a signi fi cant improvement in ...our ...
9
The inclusion of real world evidence in clinical development planning
... trial. Data on relapses were simulated from the results of the ...NMA, patients of an alternative TRANSFORMS trial were simu- lated and analysed using a negative binomial regression model as described ...of ...
12
Association of Gender with Efficacy of Immunotherapy in Metastatic Melanoma
... Pre-clinical data from animal models suggest that the anti-tumor efficacy of immune checkpoint blockade agents may be influenced by gender specific sex ...of clinical data aimed at addressing ...
7
Expert clinical management of autoimmune hepatitis in the real world
... All experts surveyed routinely use predniso(lo)ne as initial treatment for AIH, but there is a wide variation in the dose and time that is taken to taper the dose. While a minority of respondents start therapy with a ...
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<p>Real-World Data Of Osimertinib In Patients With Pretreated Non-Small Cell Lung Cancer: A Retrospective Study</p>
... among patients with T790M ...in patients with T790M positive advanced NSCLC after progression of fi rst-line EGFR-TKI ...9 Data of osimertinib in treatment naive patients of AURA study 10 and ...
9
<p>Real-World Use Of Ultrathin-Strut Biodegradable Polymer–Coated Sirolimus-Eluting Stents In Patients With Coronary Artery Disease: 6-Month Clinical Outcomes</p>
... CAD patients (aged ≥ 18 years) who underwent implantation of at least one Tetri fl ex SES between March 2017, and March 2018 were included in this ...good clinical practice and Declaration of Helsinki, and ...
9
Longitudinal clinical outcomes in a real-world population of patients with idiopathic pulmonary fibrosis: the PROOF registry
... all patients during follow-up was ...of patients with IPF in Central and Eastern Europe [EMPIRE]) reported a lung transplant rate during follow-up of ...in patients with IPF ...all patients ...
12
Patterns of hydroxyurea use and clinical outcomes among patients with polycythemia vera in real-world clinical practice: a chart review
... such patients required combined therapy with PBT and continued ...that patients with elevated Hct or elevated WBC count are at a significantly higher risk for cardiovascu- lar morbidity and mortality [4, ...
10
Retrospective Observational Study to Observe Clinical Effectiveness of Add on Canagliflozin 100 mg in Indian Type 2 Diabetes Patients with BMI>25 kg/m2, in Real World Clinical Setting A Specialized Population of Group A/B Officers Employees of Financial and Public Sectors
... enrolled patients and changes in treatment ...(588) patients were group A/B ...subjects. Data regarding age, sex, income, family history of diabetes mellitus and details regarding exercise was ...
9
Real world data: an opportunity to supplement existing evidence for the use of long-established medicines in health care decision making
... These data can now allow scrutiny at a granular level and have the potential to inform dosing, the types of patients who are prescribed a particular medication, and the impact of the use of a pharmaceutical ...
10
Early clinical experiences with nintedanib in three UK tertiary interstitial lung disease centres
... limited data regarding clinical experiences with nintedanib in the real world, in patients who are older, with co-morbidities and who may not fit the strin- gent criteria required for ...
9
The effect of bivalirudin and closure device on bleeding outcomes after percutaneous coronary interventions
... among patients receiving bivalirudin compared with heparin, especially among women ( ...this real world database representing current clinical practice benefited from the use of bivalirudin ...
9
On real-world patients and real-world outcomes : the Leiden Routine Outcome Monitoring Study in patients with mood, anxiety and somatoform disorders
... the patients with depressive disorders do not achieve remission after several adequate treatment trials (Rush et ...which patients are at risk for an unfavourable outcome is of high clinical ...
185
Real-world usage and clinical outcomes of alectinib among post-crizotinib progression anaplastic lymphoma kinase positive non-small-cell lung cancer patients in the USA
... of patients with NSCLC, and have seen at least 1 NSCLC ALK + patient in the past ...exist). Patients who participated in an NSCLC-related clinical trial prior to crizotinib and alectinib were ...
8
WillettK ISTI 4thACRE SEP2011
... • With real world data we do not have the luxury of knowing the truth – we CANNOT measure. closeness to real world truth of any one data- product[r] ...
23
Collagen fleece-bound fibrin sealant is not associated with an increased risk of thromboembolic events or major bleeding after its use for haemostasis in surgery: a prospective multicentre surveillance study
... All patients had to pro- vide written informed consent, which could be obtained either before or after ...of patients who did not subsequently receive TachoSil, a considerable burden on the time and ...
8
Original Article The clinical characteristics of metabolic syndrome in patients with acute myocardial infarction in the real world
... Patients were included if they met the univer- sal definition of AMI [7] and had no document- ed history of other cardiovascular diseases (valvular heart diseases, left ventricular dys- function, left ventricular ...
10
Real-world effectiveness and safety of oral anticoagulation strategies in atrial fibrillation: a cohort study based on a German claims dataset
... Rivaroxaban patients started with the AF approval of that drug on December 01, 2012; Dabigatran ATC: B01AE07, inclusion started on January 01, 2011; Apixaban ATC B01AX08/B01AF02, inclusion started on January 01, ...
10
PROMISE international; a clinical post marketing trial investigating the percutaneous deep vein arterialization (LimFlow) in the treatment of no-option chronic limb ischemia patient
... To facilitate constant blood flow through the newly-cre- ated crossing from artery to vein, a stent graft needs to be inserted. The LimFlow stent grafts product line con- tains of different self-expanding stent graft ...
9