receptor recognition
Poliovirus variants selected on mutant receptor-expressing cells identify capsid residues that expand receptor recognition.
... a receptor in the mouse central nervous ...mouse receptor are located in the interior of the capsid and are believed to expand receptor recognition by affecting capsid transitions during cell ...
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Receptor Recognition Mechanisms of Coronaviruses: a Decade of Structural Studies
... Receptor recognition by viruses is the first and essential step of viral infections of host cells ...a receptor- binding S1 subunit and a membrane-fusion S2 ...a receptor-binding domain ...its ...
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Structural and Functional Relationship between the Receptor Recognition and Neuraminidase Activities of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein: Receptor Recognition Is Dependent on Neuraminidase Activity
... and receptor recognition ...the receptor recognition activity of these proteins, indicating that the receptor recognition deficiencies of the mutated HN proteins result from ...
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Neutralization map of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus: domains recognized by monoclonal antibodies that prevent receptor recognition.
... 9 Neutralization Map of the Hemagglutinin-Neuraminidase Glycoprotein of Newcastle Disease Virus: Domains Recognized by Monoclonal Antibodies That Prevent Receptor Recognition RONALD M.. [r] ...
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Parvovirus Capsid Structures Required for Infection: Mutations Controlling Receptor Recognition and Protease Cleavages
... controls the host range (23, 36, 37, 40, 44). Residue 300, which we show here controls the virus after cell entry, has also been shown in other cases to control receptor binding, tropism, and host range. One of ...
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Species-Specific Receptor Recognition by a Minor-Group Human Rhinovirus (HRV): HRV Serotype 1A Distinguishes between the Murine and the Human Low-Density Lipoprotein Receptor
... HRV1A does not bind to human LDLR expressed in mouse M4 cells. In order to confirm the absence of binding of HRV1A to human LDLR, this receptor was expressed in M4 cells. The entire human LDLR cDNA and a construct ...
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Receptor Recognition of and Immune Intracellular Pathways for Veillonella parvula Lipopolysaccharide
... TLR4 is the major receptor for V. parvula LPS-induced cytokine production in mice. Resident peritoneal macrophages were harvested from TLR2 ⫺/⫺ and TLR4 ⫺/⫺ mice and their control littermates and stimulated in ...
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Receptor recognition of maleyl albumin induces chemotaxis in human monocytes
... to receptor- independent plasma transport functions, may also play an important role in the receptor- mediated recruitment and accumulation of phagocytic cells at sites of inflammation and ...
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Analysis of Influenza Virus Hemagglutinin Receptor Binding Mutants with Limited Receptor Recognition Properties and Conditional Replication Characteristics
... the receptor binding ...the receptor binding pocket, is quite distal ( ⬃ 40 Å) from HA1 position 238, which in WT HA forms an ion pair with the glutamic acid at HA2 position 72 of a neighboring ...the ...
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Comprehensive Analysis of Ebola Virus GP1 in Viral Entry
... in receptor recognition or protein folding, 103 indi- vidual residues within the N-terminal 230-residue region of GP1, which is conserved among different Ebola virus species, were targeted by ...
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Mutations in the Stalk of the Measles Virus Hemagglutinin Protein Decrease Fusion but Do Not Interfere with Virus-Specific Interaction with the Homologous Fusion Protein
... on the functions of MV H. Subsequently, F96 was also mutated to leucine. Another mutation, I99A, which is located between the third and fourth heptadic residues, was also characterized. Each of the mutated proteins is ...
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Cryo-Electron Microscopy Structure of Porcine Deltacoronavirus Spike Protein in the Prefusion State
... three receptor-binding S1 subunits that tightly pack into a crown-like structure and three membrane fusion S2 subunits that form a ...unidentified receptor on host cell ...concealed receptor- binding ...
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Characteristics of NMDA receptor ligands in rodent brain in vivo & in vitro under normal conditions and after chronic ischaemia
... although subsequent findings have suggested the exisence of AMPA-operated Ca"*^ channels on intemeurones (Ozawa, 1991). The kynurenate derivatives 6,7- dinitroquinoxaline-2,3 -dione (DNQX) and ...
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Co receptor CD8 mediated modulation of T cell receptor functional sensitivity and epitope recognition degeneracy
... The present model indicates that intermediate levels of CD8 are associated with the lowest functional sensitivity. This suggests the following mechanism to maintain quiescent (naïve) T-cells in a rel- atively ...
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Purification of a HeLa cell receptor protein for group B coxsackieviruses.
... We propose that Rp-a is a protein in the plasma membrane receptor complex which is responsible for the specific recognition and binding of the group B coxsackieviruses... The gradient wa[r] ...
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Two distinct receptors account for recognition of maleyl albumin in human monocytes during differentiation in vitro
... The recognition of both ligands by the scavenger receptor of these cells has been ...surface receptor for maleyl-albumin that is distinct from the scavenger ...maleyl-albumin receptor, ...
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Speech Recognition for English Language Pattern Recognition Approach
... Initially we applied the sound signal to this component, the input signals are induced to this component directly or first we can record it, after that the recorded sound may be injected to it, the input sound will be ...
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Injury affects coelomic fluid proteome of the common starfish, Asterias rubens
... hindering recognition of injury-specific physiological ...non-self- recognition; (2) regulation of proteolysis by a rich repertoire of peptidase inhibitors; (3) activation of proteolysis and degradation of ...
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The Role of Cytosolic Access in Streptococcus Pneumoniae Nasopharyngeal Colonization
... P38 MAPK senses a diversity of bacterial toxins including proaerolysin (116) and streptolysin O (223), a cytolysin in the same toxin family as pneumolysin, and plays an important role in host defense. Activation of p38 ...
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Constitutive Expression of a Bacterial Pattern Recognition Receptor, CD14, in Human Salivary Glands and Secretion as a Soluble Form in Saliva
... tion receptor, sCD14, into saliva and that salivary CD14 me- diated the activation of CD14-lacking intestinal epithelial cells by LPS in a TLR4-dependent manner, suggesting that salivary CD14 is important for the ...
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