receptor subunits
Differential localization of glutamate receptor subunits at the drosophila neuromuscular junction
... When presynaptic inputs that use different neurotransmitters, such as GABA or glutamate, converge on a single postsynaptic target, the postsynaptic receptors that cluster at each terminal match the presynaptic ...
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Identification of residues within GABA(A) receptor subunits that mediate specific assembly with receptor β subunits
... with receptor  subunits in a similar manner, as observed on deletion of residues ...on receptor cell surface ...of subunits or may alternatively be important in controlling subunit structure, ...
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The effect of sodium salicylate on the level of GABAB receptor subunits in the rat's central auditory system
... Figure 8 The effect of SS on the level of GABA B R1 and GABA B R2 receptor subunits in major auditory structures: Western blotting results .... 54.[r] ...
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Characterisation of γ-aminobutyric acid B receptor subunits and related proteins in the rat central nervous system
... lb receptor subunits co-localise to the same cell, as do GABAbi and GABAb 2 receptor ...GABABib receptor subunits suggested that agonists and antagonists which could be developed ...
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NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina
... We previously reported that GluN2D deficiency pre- vented loss of RGCs in GLAST KO mice [15]. These re- sults suggest that both GluN2B and GluN2D subunits play a critical role in RGC degeneration by glutamate ...
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Nuclear import pathway of the cytokine interleukin-5 and its receptor subunits
... If it does, this should further contribute to the growing idea that polypeptide ligand/receptor nuclear import is a key means of activating specific growth factor and cytokine signalling[r] ...
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... glutamate receptor subunits in the rat red ...receptor subunits. The results showed that all ionotropic glutamate receptor subunits are expressed in the red ...glutamate ...
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Studies on the phosphorylation of GABAA receptor β subunits
... GABAa-R subunits the p i subunit alone has been shown to be phosphorylated by PKA activation in a cellular ...of receptor function (Moss et ...that receptor p subunits alone are substrates for ...
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Ion channels as insecticide targets
... & Reenan, 2000). In the RNA editing process, post-transcrip- tional editing of pre-mRNAs, through the action of dsRNA adenosine deaminases, modifies adenosine (A) residues to inosine (I), which then alters the coding ...
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Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing
... The most likely site of the initial IHC dysfunction is the post- synaptic region of the afferent synapse rather than the pre-synaptic complex, for a number of reasons. Firstly, resting membrane poten- tial, basolateral ...
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Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity
... receptor subunits. Amplitudes of whole-cell cur- rents evoked by AMPA receptor agonists were dramatically larger in LSC motor neurons than OM neu- ...AMPA receptor current between the two ...
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Interleukin 18 in the CNS
... its receptor subunits were now demonstrated to be broadly expressed in ...its receptor subunit alpha is helping to decipher the action of this cytokine in the ...IL-18 receptor subunits ...
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Studies of NMDA receptor function and stoichiometry with truncated and tandem subunits
... The subunits that compose eukaryotic glutamate ion channel receptors have three transmembrane domains (TMs) and terminate with intracellular tails that are important for controlling channel expression and ...NMDA ...
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Host cell-specific folding of the neuronal nicotinic acetylcholine receptor α7 and α8 subunits
... Later reports suggest that the a 5 gene product, also estimated to be -5 0 kDa, may have been co-isolated by mAb35 during the immunopurification of nAChRs from chick brain (Whiting et al, 1991b; Conroy et al, 1992). The ...
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G proteins transducing receptor-mediated inhibition of the M-type K+ current in rat cultured sympathetic neurones
... agonist-occupied receptor to the equilibrium increased the inhibition of Ik(M) suggests that there is a spare G protein capacity available for transducing this response (thus, in the above scheme [G] > > ...
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The organization of proteins involved in synaptic plasticity
... dependent while GluA2/3 receptor trafficking is constitutive, but it remains unknown if GluA1/2 and GluA2/3 receptor insertion follows the same route into the synapse. Multiple studies suggest that AMPAR ...
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P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes
... P2X receptor for larger cations, which may underlie the generation of the delayed current ...P2X receptor is not permeable to NMDG, and re- moval of small cations should eliminate ionic current through P2X ...
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Differential regulation of lymphokine production by distinct subunits of the T cell interleukin 2 receptor
... affinity receptor which consists of a heterodimer composed of two distinct IL-2-binding proteins (IL- 2R alpha/IL-2R ...the receptor-specific regulatory effects of IL-2 on ...
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Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
... There are probably several mechanisms that can cause decreases in insulin signaling via the PI 3-kinase path- way in the vasculature of obese insulin-resistant rats. First, increases in serine and threonine ...
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Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa
... alpha subunits of the vitronectin receptor (VNR alpha), the fibronectin receptor (FNR alpha), and for the alpha subunit of the platelet glycoprotein IIb/IIIa complex, ...alpha subunits do not ...
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