Recombinant FSH
Differential gene expression in human granulosa cells from recombinant FSH versus human menopausal gonadotropin ovarian stimulation protocols
... between recombinant FSH and hMG proto- ...the FSH isoform profiles and potentially in specific FSH activity that may contribute to the differences in gene expression ...
6
Recombinant FSH Compared to Clomiphene Citrate as the First-Line in Ovulation Induction in Polycystic Ovary Syndrome Using Newly Designed Pens: A Randomized Controlled Trial
... Alternatives other than CC are aromatase inhibitors like letrozole which is considered to have more favorable ovarian and endometrial effects (3). Nonetheless, there are concerns regarding interruption with normal ...
7
Probabilistic cost-effectiveness analysis of controlled ovarian stimulation with recombinant FSH plus recombinant LH vs. human menopausal gonadotropin for women undergoing IVF
... of recombinant FSH plus recombinant LH in 2:1 ratio (Pergoveris, Merck, Germany) may be used not only to induce ovulation in anovulatory women with hypogonadotropic hypogonadism [14], but also to ...
11
Comparison of highly purified urinary versus recombinant FSH: Effect on ART outcomes in polycystic ovary syndrome
... purified FSH with approximately 4% impurities and less than ...1988 recombinant FSH (rFSH) was prepared by transfecting Chinese hamster ovary cell lines with both FSH subunit genes ...patients ...
8
Controlled Ovarian Stimulation with recombinant-FSH plus recombinant-LH vs. human Menopausal Gonadotropin based on the number of retrieved oocytes: results from a routine clinical practice in a real-life population
... the recombinant molecule [6, 7]. After recombinant Luteinizing Hormone (rLH) was made available, both retrospective [8, 9] and prospective [10–14] studies re- ported that rLH addition to rFSH was unable to ...
8
Effects of recombinant LH supplementation to recombinant FSH during induced ovarian stimulation in the GnRH-agonist protocol: a matched case-control study
... Therefore, there is a need for further clinical research to establish appropriate clinical criteria for LH supplementa- tion. FSH plays a crucial role in recruitment, selection, and dominance, while LH contributes ...
8
Anti-tumor Effects of Targeted Follicle-stimulating Hormone-lytic Peptide Conjugates in Prostate Cancer (PC-3) Xenograft Mouse Model
... the FSH-Phor18 in killing tumors and can be more effective than targeting other known markers because many of these markers ...the recombinant FSH treatment restored serum inhibin-B levels and ...
8
Recurrent Pregnancy Loss in Patients with Polycystic Ovary Syndrome: A Case Control Study
... Many researchers have studied adverse obstetric outcome in PCOS patients, apart from pregnancy loss. In a recent meta-analysis by Qin et al. , they found that PCOS patients had higher incidence of pregnancy induced ...
13
Controlled ovarian stimulation with r-FSH plus r-LH vs. HMG plus r-FSH in patients candidate for IVF/ICSI cycles: An RCT
... with recombinant FSH (Gonal-F, Serono, Switzerland) (75 IU per ampoule) and after six days the recombinant LH (Levuris, Serono, Switzerland), 75 IU subcutaneously ...
6
Review of the safety, efficacy, costs and patient acceptability of recombinant follicle-stimulating hormone for injection in assisting ovulation induction in infertile women
... follitropin). FSH is derived from urine or is produced as recombinant ...of recombinant FSH are available – follitropin alpha and fol- litropin ...of recombinant FSH, we ...
7
Continuous follicle-stimulating hormone exposure from pituitary adenoma causes periodic follicle recruitment and atresia, which mimics ovarian hyperstimulation syndrome
... After the operation, she suffered from abdominal disten- sion again. She consulted with Sapporo Medical University Hospital to investigate the cause. We noticed that her preexisting medical condition was quite similar to ...
5
Recombinant versus highly-purified, urinary follicle-stimulating hormone (r-FSH vs. HP-uFSH) in ovulation induction: a prospective, randomized study with cost-minimization analysis
... On the other hand, only a few trials have compared r-FSH and uFSH in subfertile patients undergoing ovulation induction associated with intrauterine insemination (IUI) or timed sexual intercourse [9-14]. The ...
7
Immune effects of Alarelin on ovarian development and GnRH receptor mRNA expression levels of pituitary in tilapia (Oreochromis niloticus)
... the FSH-β and LH-β concentrations remained unchanged in the control fish, whereas the injection of alarelin significantly increased the FSH-β and LH-β concentrations from day 30 to day 40, although they ...
8
Antibody to human follicle stimulating hormone: cross reactivity with three other hormones
... the FSH- 131 I-binding antibody failed to distinguish the four human glycoprotein hormones: FSH, luteinizing hormone, chorionic gonadotropin, and thyrotropin, purified as well as endogenous hormone in ...
9
Discordances between follicle stimulating hormone (FSH) and anti-Müllerian hormone (AMH) in female infertility
... normal FSH and AMH if values fell within age-specific (as-) 95% confidence intervals (CI), and to suffer from diminished ovarian reserve (DOR) if FSH exceeded and/or AMH fell below ...AMH/abnormal ...
7
The impact of FSH receptor polymorphism on time to pregnancy: a cross sectional single centre study
... In-vitro studies have shown that the A allele at the 29th position in the 5′ untranslated region of the FSHR gene is associated with impaired transcriptional activity [13]. The polymorphism at position 29 in the promoter ...
8
Development and application of a bioassay for follicle stimulating hormone : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University
... Fig 5.5 Comparison of bioactive FSH concentrations obtained by CHO FSHR-R cell bioassay • and FSH concentrations obtained by radio receptor assay D and radioimmunoassay ~ in HPLC fract[r] ...
145
Bayesian estimation of associations between identified longitudinal hormone subgroups and age at final menstrual period
... individuals sharing similar hormone trajectory patterns over time, our approach integrated additional statistical concepts (including robust inference and semi-parametric smoothing methods), modeled within-woman ...
10
Hormonal Imbalance in Polycystic Ovarian Syndrome (Pcos) in Teaching Hospitals in Ekiti State, Nigeria
... hormone. FSH is synthesis and secreted by the gonadotropic cells of the anterior pituitary gland and regulates the development, growth, puberty matura- tion, and reproductive process of the body ...of FSH ...
9
Development and application of a bioassay for follicle stimulating hormone : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University
... Comparison of bioactive FSH concentrations obtained by CHO FSHR-R cell bioassay and FSH concentrations obtained by radio receptor assay and radioimmunoassay in HPLC fractions of purified[r] ...
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