Recombinant human growth hormone
Effects of recombinant human growth hormone administration on cardiovascular risk factors in obese children with relative growth hormone deficiency
... Collectively, all the above studies suggested that the re- duced GH secretion in obesity might cause cardiovascular consequences. Thus we assume that recombinant human growth hormone (rhGH) ...
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Effects of Different Buffers and pH on the Stability of Recombinant Human Growth Hormone
... Recombinant Human Growth hormone (rHGH) is a pharmaceutical single-chain polypeptide that contains 191 amino acids, with two disulfide ...
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Metabolic clearance of recombinant human growth hormone in health and chronic renal failure
... Despite the increasing therapeutic use of recombinant human growth hormone (rhGH), its metabolic clearance has not been investigated in detail. To evaluate the kinetics of rhGH as a possible ...
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Exuberant response to late onset of recombinant human growth hormone (rhgh) in patient with pan hypopituitarism: Case Report
... with hormone replacement, which is a simple solution but it can’t be done to physiological levels, and besides it is difficult to monitor treatment response (Smith, ...with growth disorder due to GH ...
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Growth Hormone Stimulation Test Results as Predictors of Recombinant Human Growth Hormone Treatment Outcomes: Preliminary Analysis of the National Cooperative Growth Study Database
... wrist and knee bone age determination also was derived. There were 990 patients in the study; in 925 (677 boys), there were both hand–wrist and knee bone age determi- nations from the baseline pubertal radiographs. There ...
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Comparative pharmacokinetics and pharmacodynamics of a PEGylated recombinant human growth hormone and daily recombinant human growth hormone in growth hormone-deficient children
... Recombinant human growth hormone (rhGH) is primarily used to treat children with growth failure due to endogenous growth hormone deficiency ...used growth ...
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Effects of 4 Weeks Recombinant Human Growth Hormone Administration on Insulin Resistance of Skeletal Muscle in Rats
... 41. Cartee GD. What insights into age-related changes in skeletal muscle are provided by animal models? J Gerontol A Biol Sci Med Sci 1995;50 Spec No:137-41. 42. Christopher M, Hew FL, Oakley M, Rantzau C, Alford F. ...
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The effects of recombinant human growth hormone on skin, muscle and nerve
... adult growth hormone-deficient patients before and after six to twelve months of recombinant human growth hormone (r-hGH) treatment, as part o f a double-blind placebo controlled ...
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Efficacy and Safety of Sustained Release Recombinant Human Growth Hormone in Korean Adults with Growth Hormone Deficiency
... In this study, we evaluated adverse events related to growth hormone use. If the local injection site reactions of SR-rh- GH were more severe than the ones with daily injections, the use of SR-rhGH would be ...
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Recombinant human growth hormone: a medical miracle or cause for concern?
... Human growth hormone (hGH) plays an important role in cell regeneration, growth and maintaining healthy human ...The hormone is naturally produced by somatropic cells in the ...
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The Effect of Recombinant Human Growth Hormone in Children With X-Linked Hypophosphatemia
... The growth velocity z-score was determined using this formula: (actual growth velocity ...expected growth velocity for age and gender ...of growth velocity for age and gender .1 year). Height ...
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Considerations Related to the Use of Recombinant Human Growth Hormone in Children
... of human GH in a variety of disorders (Table 2) has been stimulated by both the success of human GH therapy in GH-deficient individuals of short stat- ure and the ready availability of synthetic GH prod- ...
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The use of recombinant human growth hormone in patients with Mucopolysaccharidoses and growth hormone deficiency: a case series
... affect growth potential in the general paedi- atric population [26], at least in pre-pubertal GH-defi- cient patients treated with rhGH doses not greater than ...
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Effects of Low-Dose Recombinant Human Growth Hormone on Bone Densities of Radius, Tibia and 4th Lumbar Vertebrae in Rabbits
... In acromegaly there are supraphysiologic levels of GH. There are many studies that have investigated effects of GH on bone in acromegalic patients but the results are controversial and decrease 13 or increase 15 in the ...
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Recombinant Human Growth Hormone Treatment for Dilated Cardiomyopathy in Children
... In this prospective, single-center, randomized, partially blinded, crossover trial, recombinant hu- man GH was administered to 8 pediatric patients with stable chronic heart failure secondary to DCM. Because of ...
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Recombinant Human Growth Hormone in the Treatment of Patients With Cystic Fibrosis
... TABLE 1 Continued Study Study Design Country Study Funding Quality Rating Product Dose Follow-up Time Inclusion Criteria Exclusion Criteria Hardin et al 25 (2005) RCT United States Indus[r] ...
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Use of localized human growth hormone and testosterone injections in addition to manual therapy and exercise for lower back pain: a case series with 12-month follow-up
... of recombinant human growth hormone and testosterone to the painful and dysfunctional areas in individuals with chronic lower back pain were ...
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Is there “seasonal” variation in height velocity in children treated with growth hormone? Data from the National Cooperative Growth Study
... of growth during the spring/summer than in the winter ...on growth hormone (GH) therapy [3-5] and has not specifically been evaluated with respect to number of daylight ...Cooperative Growth ...
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Recombinant growth hormone therapy in a girl with costello syndrome: a 4-year observation
... endogenous growth hormone de- ficiency have also been documented in the literature ...and growth hormone deficiency in this condition, growth hormone therapy is often consid- ...
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Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment
... Recombinant human growth hormone (rhGH) promotes human T cell engraftment in mice with severe combined immunodeficiency, suggesting that rhGH may have effects on T cell adhesion and ...
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