Recombinant vaccinia virus
Cell surface expression of human cytomegalovirus (HCMV) gp55-116 (gB): use of HCMV-recombinant vaccinia virus-infected cells in analysis of the human neutralizing antibody response.
... Utilizing HeLa cells infected with the gp55-116 recombinant vaccinia virus as a specific immunosorbent, we have shown that approximately 40 to 70% of the total serum virus-neutralizing a[r] ...
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Altered Plaque Formation by Recombinant Vaccinia Virus Expressing Simian Immunodeficiency Virus Nef
... the virus from a group of asymptomatic, long-term human survivors who were infected with HIV type 1 (HIV-1) by blood transfusions from a single donor found the donor virus to contain a deletion in the nef ...
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Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene
... and recombinant viral vectors and com- binations thereof has been described in numerous reports (2, 3, 6, 8, 10, 13, 20, ...modified vaccinia virus Ankara (MVA) and replication-defective adenovirus ...
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Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions.
... To determine what protein products were translated in vivo from the Sindbis-specific transcripts, BSC-40 cells infected with wild-type vaccinia virus, vaccinia recombinant VV3S-7, or Sin[r] ...
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Identification and expression of a murine cytomegalovirus early gene coding for an Fc receptor.
... Identification of the murine cytomegalovirus glycoprotein B gene and its expression by recombinant vaccinia virus.. Protein structure and intracellular stability.[r] ...
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Expression of the M gene of vesicular stomatitis virus cloned in various vaccinia virus vectors.
... CV-1 cells infected with wild-type vaccinia virus or T7 polymerase recombinant vaccinia virus vTF1-6,2 were transfected by calcium phosphate precipitation with the M genecontaining plasm[r] ...
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Immunization with nonstructural proteins promotes functional recovery of alphavirus-infected neurons.
... nsP recombinant vaccinia virus-immunized mice after NSV challenge, but the antibody levels were similar to those in vaccinia virus-immunized ...the virus and the maturity of the ...
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The L protein of Rift Valley fever virus can rescue viral ribonucleoproteins and transcribe synthetic genome-like RNA molecules.
... RVF virus L protein via a recombinant vaccinia virus and assayed it for transcriptase ...the recombinant L ...with vaccinia virus express- ing the L protein, we ...
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CpG-Containing Oligonucleotides Are Efficient Adjuvants for Induction of Protective Antiviral Immune Responses with T-Cell Peptide Vaccines
... choriomeningitis virus (LCMV) or with recombinant vaccinia virus expressing the LCMV glycoprotein was achieved by immunizing mice with the immunodominant major histocompatibility complex class ...
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Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection.
... Here we show that a single immunization with a recombinant vaccinia virus-lymphocytic choriomeningitis virus LCMV vaccine VVNPaal-201 expressing the immunodominant epitope completely pro[r] ...
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Recombinant influenza virus polymerase: requirement of both 5' and 3' viral ends for endonuclease activity.
... Nuclear extracts of cells that express influenza virus polymerase through recombinant vaccinia virus infection did not display specific endonuclease activity in vitro.. This polymerase p[r] ...
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Identification of a TAP-Independent, Immunoproteasome-Dependent CD8+ T-Cell Epitope in Epstein-Barr Virus Latent Membrane Protein 2
... a recombinant vaccinia virus expressing LMP2 (vLMP2) or a control virus, vTK⫺, or preexposed to the cog- nate epitope peptide or to dimethyl sulfoxide (DMSO) solvent control and then used as ...
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Progress on new vaccine strategies against chronic viral infections
... DNA, recombinant vaccinia virus with protein boost strategies in an effort to elicit broadly neutralizing antibody in addition to CD4 + and CD8 + T cell ...
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Poliovirus capsid proteins derived from P1 precursors with glutamine-valine cleavage sites have defects in assembly and RNA encapsidation.
... The recombinant vaccinia virus-expressed mutant P1 polyproteins were analyzed for proteolytic processing defects in cells coinfected with a recombinant vaccinia virus VVP3 that expresses[r] ...
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Increased expression in vivo and in vitro of foreign genes directed by A-type inclusion body hybrid promoters in recombinant vaccinia viruses.
... Recombinant vaccinia virus could express influenza virus hemagglutinin via the hybrid promoter more efficiently, induced higher levels of neutralizing antibody and cytotoxic T lymphocyte[r] ...
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Induction of cytotoxic T cells to a cross-reactive epitope in the hepatitis C virus nonstructural RNA polymerase-like protein.
... However, because we cannot use a vaccinia virus recombinant to stimulate spleen cells from mice immunized with a recombinant vaccinia virus without activating a vaccinia virusspecific re[r] ...
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Recovery of NV Knockout Infectious Hematopoietic Necrosis Virus Expressing Foreign Genes
... necrosis virus (IHNV) is a Novirhabdovirus and is the causative agent of a devas- tating acute, lethal disease in wild and farmed rainbow ...The virus is enzootic throughout western North America and has ...
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Immediate-Early Transactivator Rta of Epstein-Barr Virus (EBV) Shows Multiple Epitopes Recognized by EBV-Specific Cytotoxic T Lymphocytes
... Epstein-Barr virus (EBV) for its role as a target for specific cytotoxic T lymphocytes ...with recombinant vaccinia virus containing the gene for Rta, we showed that six of eight Rta-specific ...
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Human Herpesvirus 6 Variant A Glycoprotein H-Glycoprotein L-Glycoprotein Q Complex Associates with Human CD46
... the recombinant vac- cinia virus vTF7 (expressing T7 RNA ...the recombinant vaccinia virus vTF7 and subsequently transfected with plasmids pcDNA-UgH and ...
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Protection against lethal cytomegalovirus infection by a recombinant vaccine containing a single nonameric T-cell epitope.
... Spleen cells from mice primed with the recombinant vaccinia virus MCMV-ieI-VAC, encoding pp89 left panel, or with the recombinant AS-mer, encoding a deletion mutant of pp89 that lacks th[r] ...
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