Redox signaling
Redox signaling in colonial hydroids: many pathways for peroxide
... Catalase, conversely, is a large (350·kDa) tetramer and is likely not taken up by a colony, nor can its enzymatic function be transferred across a plasma membrane. The lack of an effect on ROS levels of mitochondria-rich ...
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Nicotinamide adenine dinucleotide phosphate oxidase-mediated redox signaling and vascular remodeling by 16α-hydroxyestrone in human pulmonary artery cells
... Major findings from our study show that in PASMCs from female subjects, the estrogen metabolite 16αOHE1 induces ROS production, downregulates the protective antioxidant effects of Nrf2, stimulates redox ...
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Investigations of DNA-Mediated Redox Signaling Between E.coli DNA Repair Pathways
... We have uncovered details about the effect of the protein expression levels on the efficiency of DNA-mediated redox signaling for DNA lesion detection. EndoIII is the preferred redox-signaling ...
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Original Article Hepatitis B virus X stimulates redox signaling through activation of ataxia telangiectasia mutated kinase
... HBX-mediated signaling pathways are closely correlated with intracellular ROS lev- ...of redox system functions [15, ...Nrf2 signaling might be the key to the enhanced cell survival observed in the ...
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Redox signaling in the growth and development of colonial hydroids
... and redox signaling (Nishikawa et ...a redox gradient can differentially affect the timing of polyp and stolon tip development, adaptive changes in the local pattern of colony development can ...
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Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity, and Aging
... potential redox signaling from NADPH oxidase in response to exercise training to mediate the oxidative stress response in ...to redox signaling to activate the Nrf2 oxidative stress response ...
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Series Introduction: The expanding network of redox signaling: new observations, complexities, and perspectives
... in redox signaling. One of the most intriguing aspects of redox signaling and oxidative stress is that proteins involved in the trans- duction of cellular redox changes have recently ...
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Redox signaling in pathophysiology of hypertension
... the redox signaling is by and large very similar and unveil no apparent differences among these types of ...same signaling is also proposed to mediate the in- crease in sympathetic nerve activity, ...
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RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death
... Redox mechanisms play an important role in the control of various signaling pathways. Here, we report that Second mitochondrial activator of caspases (Smac) mimetic-induced cell death is regulated by ...
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Redox Signaling in Eukaryotic DNA Replication and Repair
... documented redox signaling using DNA CT between DNA repair proteins with [4Fe4S] clusters by atomic force microscopy ( 3,4,6 ), even using repair protein partners from different ...that redox ...
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Commensal microbiota induced redox signaling activates proliferative signals in the intestinal stem cell microenvironment
... intrinsic signaling that is initiated via local growth factors and other small ...cell signaling via their effects on ‘ sensor ’ proteins that are typically characterized by oxidant- sensitive cysteine ...
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Acute High-Intensity Interval Exercise-Induced Redox Signaling Is Associated with Enhanced Insulin Sensitivity in Obese Middle-Aged Men
... contradictory redox shift between plasma (decreased oxidative stress) and skeletal muscle (increased oxidative stress) may reflect the inability of plasma to accurately reflect skeletal muscle redox status ...
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<p>Geniposide Balances the Redox Signaling to Mediate Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells</p>
... the redox status of diabetic rat liver microsomes had been observed with a signi fi cant increase of reduced thiol groups in polypep- tide chain of PDI and more oxidized disul fi de bonds in ...cellular redox ...
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RETRACTED ARTICLE: The quantum physiology of oxygen; from electrons to the evolution of redox signaling in the human brain
... Fig. 4 a Evolution of genes encoding the hypoxia-inducible factor (HIF) pathway and (b). Importance of mitochondrial-generated reactive oxygen species (ROS) stabilization of HIF-1 α during hypoxia including emergent ...
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Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
... the redox potential that occur during oxidative stress in the cell, we treated Brf2 with gradients of oxidized/reduced glutathione (GSSG/GSH), whose ratio increases drastically during oxidative stress (Jones, ...
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A tutorial on oxidative stress and redox signaling with application to exercise and sedentariness
... ROS below basal levels reduced the force production of skeletal muscle, while increasing ROS to a certain point increased force production, and ROS exposure above that point resulted in a reduction in force production ...
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Hydrogen peroxide – production, fate and role in redox signaling of tumor cells
... addition, redox alterations induced by se- lective inhibition of the glucose metabolism leading to massive oxidative stress might serve as a molecular switch that activates the ASK1-JNK/p38 MAPK signal- ing ...
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Thioredoxin like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF κB signaling
... the redox protein thioredoxin-like 2 (TXNL2) regulates the growth and metastasis of human breast cancer cells through a redox signaling ...into redox-based mechanisms underlying tumor growth ...
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The role of Pex11-beta in peroxisome biogenesis, intracellular relationship to reactive oxygen species levels and redox-sensitive cell signaling
... Garcia, Wood et al. 2010). High ROS levels are detrimental for growth of embryos in culture, and administering free radical scavengers improves in vitro embryo development (Covarrubias, Hernandez-Garcia et al. 2008). ...
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Mouse models for preeclampsia: disruption of redox regulated signaling
... The concept that oxidative stress contributes to the development of human preeclampsia has never been tested in genetically-defined animal models. Homozygous deletion of catechol-O- methyl transferase (Comt-/-) in ...
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