Reduced nicotinamide adenine dinucleotide (NADH)
Reduced nicotinamide adenine dinucleotide and the reduction of oxidized glutathione in human erythrocytes
... of reduced nicotinamide adenine dinucleotide (NADH), generated through the activity of lactic acid dehydrogenase, to support the reduction of endogenous oxidized glutathione in intact ...
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Deficiency of the iron sulfur clusters of mitochondrial reduced nicotinamide adenine dinucleotide ubiquinone oxidoreductase (complex I) in an infant with congenital lactic acidosis
... flavin adenine dinucleotide-linked substrate, succinate, was ...mitochondrial NADH-ubiquinone oxidoreductase (complex ...from NADH could reduce the flavin mononucleotide ...
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Glucose regulation of hydroperoxide metabolism in rat intestinal cells Stimulation of reduced nicotinamide adenine dinucleotide phosphate supply
... The stimulation of NADPH production with exogenous glucose further suggests that the flux of endogenous glucose through the pentose phosphate shunt is low, consistent with a preferential[r] ...
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Deficits in Bioenergetics and Impaired Immune Response in Granulocytes From Children With Autism
... namely reduced nicotinamide-adenine dinucleotide (NADH) oxidase, succinate oxidase, a-glycerophosphate oxidore- ductase, and cytochrome c oxidase activities, all normalized to citrate ...
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Congenital Methemoglobinemia: A Rare Cause of Cyanosis in the Newborn—A Case Report
... in reduced nicotinamide adenine dinucleotide (NADH)-cytochrome b5 reductase was suspected, and whole blood samples from the infant and his parents and 2 full siblings were ...of ...
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I ³¹P and ¹³C Nuclear Magnetic Resonance Studies of Nicotinamide Adenine Denucleotide and Related Compounds II ¹⁹F Nuclear Magnetic Resonance Studies of Rabbit Muscle Glyceraldehyde 3 Phosphate Dehydrogenase Covalently Labeled with a Trifluoromethyl Group
... *Abbreviations used in Chapter I are: NAD+, p-nicotinamideadenine dinucleotide; NADH, reduced {:;-nicotinamide-adenine dinucleotide; a-NAD+, 0:-nicotinamide-adenine dinucleotide; NMN+, n[r] ...
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Improved catalytic activity of ruthenium–arene complexes in the reduction of NAD+
... β-nicotinamide adenine dinucleotide hydrate (NAD + ) and β-nicotinamide adenine dinucleotide reduced dipotassium salt (1,4-NADH) were obtained from ...
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Possible role of nicotinamide adenine dinucleotide as an intracellular regulator of renal transport of phosphate in the rat
... and reduced (NADH) form, inhibited the Na+-dependent uptake of 32Pi in the concentration range of 10-300 microM NAD when added in vitro to BBM vesicles isolated from rat kidney cortex, but did not inhibit ...
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Streptozotocin Diabetes CORRELATION WITH EXTENT OF DEPRESSION OF PANCREATIC ISLET NICOTINAMIDE ADENINE DINUCLEOTIDE
... maximum N-nitroso intact 1-methyl-1-nitrosourea concentration of 0.162 µmol/ml and reduced the mean NAD to 0.58 pmol/islet, and was nondiabetogenic; 200 mg/kg attained a peak plasma concentration of 0.344 µmol/ml ...
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Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell free system
... When both the supernate and pellet fractions were omitted, there was no superoxide production, thus establishing that the generation of superoxide was not due to some side reaction invol[r] ...
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Carbonyl reductase identification and development of whole-cell biotransformation for highly efficient synthesis of (R)-[3,5-bis(trifluoromethyl)phenyl] ethanol
... Codexis reduced 150 g/L 3,5-BTAP to (R)-3,5-BTPE with 98–99% conver- sion and >99% ee ...of nicotinamide adenine dinucleotide phosphate [NAD(P) + ], was necessary to ...
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Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
... increase nicotinamide adenine dinucleotide phosphate (NADPH) production and counter the increase in reactive oxygen species (ROS) present under ...The reduced novel GSH synthesis under ...
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Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus
... activation ex vivo. The ROS production was not associated with corticosteroid dose or other immunotherapies. PMA induced ROS production was significantly reduced in patients with severe disease. In contrast, ...
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Non enzymatic upregulation of tissue factor expression by gamma-glutamyl transferase in human peripheral blood mononuclear cells
... LPS: Lipopolysaccharide; MTT: Dimethyl thiazolyl diphenyl tetrazolium; NAC: N-acetyl-L-cysteine; NADP: Nicotinamide adenine dinucleotide phosphate; NFkB: Nuclear factor kappa-light-chain[r] ...
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Treatment with the arginase inhibitor Nw hydroxy nor L arginine restores endothelial function in rat adjuvant induced arthritis
... modestly reduced circulating cytokines, indicating that other mechanisms than the reduction of vascular inflammation are likely involved in the beneficial effects of the ACE ...
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Label-free whole-colony imaging and metabolic analysis of metastatic pancreatic cancer by an autoregulating flexible optical system
... of NADH and FAD, which are natural biomarkers of cellular metabolism [26-29], and the scattering signals of collagen fibers and optical heterogeneity, which are large products of matrix reorganization in ...
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Expanding antitumor therapeutic windows by targeting cancer-specific nicotinamide adenine dinucleotide phosphate-biogenesis pathways
... Abstract: Nicotinamide adenine dinucleotide phosphate (NADPH) biogenesis is an essential mechanism by which both normal and cancer cells maintain redox ...
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Role of nicotinamide adenine dinucleotide and adenosine triphosphate in glucocorticoid induced cytotoxicity in susceptible lymphoid cells
... These studies suggest that steroid-induced cytotoxicity in susceptible lymphocytes is due to the presence of DNA strand breaks that activate polyADP-ribose polymerase to a sufficient deg[r] ...
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Effects of environment on the metabolism and germination of crested wheatgrass seeds.
... Seeds incorporated 32P in nicotinamide adenine dinucleotide, hexose-P, UDP-hexose, adenosine triphos- phate, inositol hexaphosphate, and other phosphate esters.. Total [r] ...
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Significant enhancement of structural stability of the hyperhalophilic ADH from Haloferax volcanii via entrapment on metal organic framework support
... The alcohol dehydrogenase from Haloferax volcanii HvADH2 utilises NADPH β- nicotinamide adenine dinucleotide phosphate as a co-factor with some activity with NADH-nicotinamide adenine di[r] ...
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