Reflectance confocal microscopy and image analysis
In vivo Reflectance Confocal Microscopy: innovations in skin imaging
... For image analysis, a list of diagnostic RCM features for AK and SCC was composed according to literature (Table ...per confocal image ...
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Reflectance confocal microscopy for diagnosing cutaneous melanoma in adults
... studies, analysis required use of an SROC curve, and to aid interpretation we quoted ’typical’ summary results assum- ing a fixed sensitivity of 90% for both ...
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Reflectance confocal microscopy for the diagnosis of skin infections and infestations
... Confocal microscopy may be particularly suited for the diagnosis of cutaneous infestations or infections as most of the pathologic clues are confined to the ...
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Reflectance confocal microscopy for diagnosising keratinocyte skin cancers in adults
... of analysis for all analyses was the lesion rather than the ...each analysis undertaken, only one dataset was included per study to avoid over-counting of ...
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Reflectance Confocal Microscopy in Melanoma and Non-melanoma Skin Cancer.
... RCM updates for examination of skin can- cers Basic principles of RCM RCM is a non-invasive method for high- resolution diagnostics of tissue. While conven- tional microscopes work by using transmitted light technology ...
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Towards implementation of in vivo Reflectance Confocal Microscopy in clinical dermatology
... Many diagnostic RCM melanoma studies were performed by international research groups. However, an overview of the subset of distinctive RCM features for melanoma and its clinical simulators was lacking. We conducted a ...
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Case Report: Melanoma and melanocytic nevus differentiation with reflectance confocal microscopy
... Reflectance confocal microscopy findings After dermoscopic evaluation and storage of both lesions in the UNIMORE digital dermoscopy database system the patient was referred for further evaluation ...
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Confocal microscopy
... optical image was seen as a great advantage of the parallel confocal ...the confocal image could be ...the image to oscillate in a direction perpendicular to the length of the slit, ...
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Cost Effectiveness of the addition of Reflectance Confocal Microscopy in the diagnostic pathway of skin cancer
... 3 Methods and Materials The diagnosis of skin cancer is currently based on the clinical-dermatoscopic pathway. Dermoscopy, or skin surface microscopy, is a noninvasive device that allows the in vivo evaluation of ...
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Difficult-to-diagnose facial melanomas: Utility of reflectance confocal microscopy in uncovering the diagnosis
... M elanoma on sun-damaged skin, commonly known as lentigo maligna (LM, akin to melanoma in situ) and lentigo maligna melanoma (akin to invasive melanoma), is mostly found on the head and neck of elderly patients. This ...
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Three-dimensional image sensing by chromatic confocal microscopy
... By using a white-light source and examining an object with a depth variation less than the axial range of the chromatic focus, we find that all parts of the object [r] ...
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Impact of in vivo reflectance confocal microscopy on the number needed to treat melanoma in doubtful lesions
... DISCUSSION The major outcome of our study is the significant reduction on the NNT as a result of the addition of RCM to dermoscopy in real clinical practice. Since the performance of the examination technique has a ...
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The value of reflectance confocal microscopy in diagnosis of flat pigmented facial lesions: a prospective study
... expert confocal readers (randomly selected) who were blinded to the clinical and dermatoscopic appearance of the lesion, the clinical diagnosis and the clinical data of the ...
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Monitoring treatment response in psoriasis: current perspectives on the clinical utility of reflectance confocal microscopy
... the confocal microscopic patterns, a multi- centric study designed and executed under the supervision of the International Confocal Group (ICG) has been conducted with the aim of the identification of ...
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Confocal Fluorescence Microscopy
... A confocal fluorescence microscope is a serial rather than parallel image- acquisition device: the object is illuminated point by point and the generated flu- orescence, imaged onto the detection pinhole, is ...
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Confocal optical microscopy
... The great advantage of the tandem scanning approach, however, is that the disc and pinholes of the illumination train are not visible to the detection optics. Only the light that actually gets through the illumination ...
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Impact of Dermoscopy and Reflectance Confocal Microscopy on the Histopathologic Diagnosis of Lentigo Maligna/Lentigo Maligna Melanoma
... Because histopathology had always represented the gold standard for the final diagnosis of melanoma, we can reasonably affirm that a long-lasting and profitable collabo- ration between clinicians and pathologists has ...
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Artifacts and landmarks: pearls and pitfalls for in vivo reflectance confocal microscopy of the skin using the tissue-coupled device
... Dark images superficially occur in a few different settings, such as eroded lesions with minimal crusting, concave lesions, and papules. Eroded lesions may appear dark superficially when the stratum corneum and stratum ...
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Confocal microscopy in the diagnosis of melanoma
... dermoscopic image; pointing the cursor at a dermoscopic structure on the digital image will focus the RCM to scan the corre- sponding location (Scope et ...under reflectance microscopy, even ...
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LASER SCANNING CONFOCAL MICROSCOPY
... These filters are limiting in several respects. Because each filter has a fixed central wavelength and passband, several filters must be utilized to provide monochromatic illumination for multispectral imaging, as well ...
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