regulatory myosin light chain
Functions of the Caenorhabditis elegans Regulatory Myosin Light Chain Genes mlc-1 and mlc-2
... Caenorhabditis elegans contains two muscle regulatory myosin light chain genes, mlc-1 and mlc-2. To determine their in vivo roles, we identified deletions that eliminate each gene individually ...
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Cloning of rainbow trout (Oncorhynchus mykiss) α actin, myosin regulatory light chain genes and the 5′ flanking region ofα tropomyosin Functional assessment of promoters
... OnmyAct), myosin regulatory light chain (OnmyMLC2) genes and the 5′-flanking region of α-tropomyosin (α- ...putative regulatory motifs (E-boxes in all three sequences and CArG-boxes in ...
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Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment
... 12, myosin regulatory light chain 2, and profilin 1) showed significant increase in their ...of myosin regulatory light chain 2 and peroxiredoxin 1 by MPA ...of ...
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Abnormal Smooth Muscle Contraction Alters Gut Motility and Propagates Epithelial invasion in the Larval Zebrafish Intestine
... on regulatory proteins involved in contraction (Seiler et ...phosphorylated myosin light chain (p-MLC) expression was assayed and found to similar between wild type and mlt suggesting that ...
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Specific distribution of overexpressed aurora B kinase in interphase normal epithelial cells
... phosphorylated myosin II regulatory light chain immunofluorescence, cells were rinsed with warm cytoskeleton buffer [17] and fixed with 4% paraformalde- hyde (EM Science) in warm cytoskeleton ...
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Regulation of human heart contractility by essential myosin light chain isoforms
... and regulatory (phosphorylatable) MLC (or MLC-2) (5, ...and regulatory MLC are associated with the neck region of the myosin-S1 fragment ...three regulatory (phosphorylatable) myosin ...
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Attenuated platelet aggregation in patients with septic shock is independent from the activity state of myosin light chain phosphorylation or a reduction in Rho kinase-dependent inhibition of myosin light chain phosphatase
... The fraction of the MLCP regulatory subunit MYPT which was phosphorylated at the inhibitory Thr855 site (i.e. the proportion of MLCP in the putative RhoA/ROK- dependent inactive state) was not different in ...
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Constraints on intron evolution in the gene encoding the myosin alkali light chain in Drosophila.
... To distinguish the past action of evolutionary forces in introns known to have regulatory information, we examined nucleotide sequence variation at 991 sites in a r[r] ...
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Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β cardiac myosin
... -cardiac myosin, the motor protein that powers ventricular ...non-cardiac myosin, there is no clear consensus about the mechanism of action of these mutations on the function of human β -cardiac ...-cardiac ...
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The Cytomegalovirus Enhancer Induces an Immediate Response to the Myosin Light Chain 2v Promoter during P19CL6 Cell Differentiation
... In the CMV enhancer (Figure 4(a)), there are sequence motifs similar to the canonical binding sites for NKX2.5 and Tbx5, 5’-TYAAGTG-3’ and 5'-(A/G) GGTGT-3', respectively [23] [24]. Since these transcription factors also ...
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A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart
... the myosin light chain kinase (MLCK) protein family that act on myosin regulatory light chain in muscle cells have been identi- fied, skeletal muscle MLCK (skMLCK) and ...
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Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice
... essential light chains (4). In the mammalian heart, the two heavy chain genes— a -MyHC and b -MyHC — have been extensively ...and regulatory my- osin light chains. Essential light ...
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Identification and characterisation of a type II myosin in the fission yeast <italic>Schizosaccharomyces pombe</italic>
... the regulatory domain and interacts with a small helix of highly conserved residues which originates at the base of the cleft neai* the putative y-phosphate binding ...the light chain binding domain ...
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Functionally significant allelic variation in myosin light chain composition in a tropical cichlid
... upper myosin light chain 1; LC1 f2 *, lower myosin light chain 1; LC n , myosin light chain 1 from ...
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HIV 1 Assembly, Release and Maturation
... of myosin light chain kinase, or of actin depolymerisation agents mycalolide B and cyto- chalasin D to reduce the transport of nascent HIV-1 pro- tein in the host cell and to disrupts Gag ...
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Protein Kinase A Regulates beta-2 Integrin Avidity Activation and Subsequent Neutrophil Activation via Modulation of Myosin Light Chain Kinase.
... phosphorylates myosin light chain (MLC) at thr18ser19 which allows activates myosin ATPase activity which is required for actin-myosin complex formation as well as myosin motor ...
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Role of calmodulin in platelet aggregation Structure activity relationship of calmodulin antagonists
... 20,000-dalton myosin light chain from platelets correlated well with the magnitude of their binding affinity to ...20,000-dalton myosin light chain ...
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A small molecule inhibitor of T gondii motility induces the posttranslational modification of myosin light chain 1 and inhibits myosin motor activity
... Isolated myosin motor complexes were resolved by SDS-PAGE along with protein standards (Phosphor- ylase b 94kDa; Albumin 67kDa; Ovalbumin 43kDa; Carbonic anhydrase 30kDa; Trypsin inhibitor ...of myosin ...
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Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II
... and myosin II. Inhibitors of ROCK, MLCK or myosin II abrogated or strongly attenuated cranial motor neuron growth cone collapse, and produced pathfinding errors in explant ...
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Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle
... [ROCK2], myosin-light chain kinase [MLCK]) as well as three standard reference genes (glyceraldehyde-3-phosphate de- hydrogenase [GAPDH], β-actin [ACTB], phosphoglycer- ate kinase 1 [PGK1]), we used ...
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