renal allograft rejection
Complement metabolism in man: hypercatabolism of the fourth (C4) and third (C3) components in patients with renal allograft rejection and hereditary angioedema (HAE)
... stable renal allograft ...experiencing renal allograft rejection had unstable levels of C4 and C3, and exhibited moderate hypercatabolism of both ...
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Increased circulating follicular helper T cells with decreased programmed death-1 in chronic renal allograft rejection
... acute rejection can regulate B-cell alloreactivity and the number of these Tfh cells alters the immunization status and DSA levels ...chronic renal allograft rejection are not known ...
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Renal epithelial cells retain primary cilia during human acute renal allograft rejection injury
... human renal allografts suffering acute tubular necrosis have shown that length of primary cilia borne by epithelial cells doubles throughout the nephron and collecting duct, and then normalises as renal ...
5
Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates
... via renal allograft to rhesus monkey ...after renal transplantation, the anergic T cells were transferred to the recipient, after which no further immunosuppressive agents were ...administered. ...
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Detection of renal allograft rejection using blood oxygen level-dependent and diffusion weighted magnetic resonance imaging: a retrospective study
... included renal allograft recipients that received renal transplantation from deceased donors in our center and were willing to accept MRI examination between April 2010 and February ...normal ...
7
Early peri-operative hyperglycaemia and renal allograft rejection in patients withoutdiabetes
... following renal transplantation independently predicted acute rejection (Odds ...oped rejection compared to 71% of patients who had a serum glucose above this ...
6
Antitumor activity of nivolumab on hemodialysis after renal allograft rejection
... and renal transplantation team, and a recommendation for anti-PD-1 treatment was made, based on available safety data and high risk of cancer-related ...in renal function prior to nivolumab ...
5
THE ROLE OF T-L YMPHOCYTE SUBPOPULATION IN RENAL ALLOGRAFT REJECTION
... The recent development of monoclonal antibodies that recognize T-cell subsets has permitted the moni toring of various immunoregulatory cell populations in allograft recipients. Several investigators have re ...
6
GC/MS based urine metabolomics analysis of renal allograft recipients with acute rejection
... drugs, renal transplantation has been employed as the preferred treatment type for patients with ESRD over the past dec- ...acute renal allograft rejection remains a vital determining factor ...
9
Pembrolizumab for metastatic melanoma in a renal allograft recipient with subsequent graft rejection and treatment response failure: a case report
... in renal transplant patients because it has been shown to be associated with long-term graft survival ...Acute allograft dysfunction in this setting is most likely to be related to acute cell-mediated re- ...
5
Synergic silencing of costimulatory molecules prevents cardiac allograft rejection
... antigen, DCs capture the antigen and express the high level of costimulatory molecules and stimulate T cell responses. Suppression of costimulatory molecules can generate tolerogenic DCs induce more Treg generation and ...
11
Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis
... the rejection episode and returned to baseline levels with its resolution), Reeve et al (genes most frequently represented in the predictive analysis for microarrays classifier), Saint-Mezard et ...cardiac, ...
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Role of tacrolimus prolonged release in the prevention of allograft rejection
... of rejection and achieving a balance between insufficient and excessive ...transplant rejection consists of 2 divided doses per ...of allograft rejection, and safety profiles in solid-organ ...
6
Chronic allograft rejection: A significant hurdle to transplant success
... There are two major hypotheses concerning the initiation of vascular remodeling and inflammatory response. Traditional concept called the “inside-out” response assumes that the inflammatory response to various types of ...
8
The study of clinico-pathological correlation and treatment outcome in acute allograft rejection in the immediate post renal transplant period
... acute rejection episodes (ARE) has a detrimental impact on long-term graft survival and is associated with MHC class I incompatibility, whereas early ARE is correlated with HLA-DR mismatches and has a better ...
8
Immunobiology of pancreatic islet and thyroid transplantation
... Further evidence for the concept of the cellular basis of allograft rejection came from studies which showed that mice made neonatall y tolerant and now carrying skin allograft s of the [r] ...
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Therapeutic lymphangiogenesis ameliorates established acute lung allograft rejection
... acute rejection of the lung allograft occurs in over half of transplant recipients, and the factors that promote lung acceptance are poorly ...lung allograft function and survival are ...established ...
15
Non-invasive molecular imaging of inflammatory macrophages in allograft rejection
... macrophage-mediated rejection as a contributing factor for the progressive decline in graft function, indicating that current immunosuppressive treatment protocols fail to keep at bay the potent effector responses ...
10
Immunosuppressive drugs in organ transplantation to prevent allograft rejection: Mode of action and side effects
... Alemtuzumab (also known as CAMPATH-1H) is a humanized rat IgG1 monoclonal antibody directed against the CD52 cell surface antigen, expressed on T cells, B cells, natural killer cells and monocytes. It results in ...
8
Hyperuricemia in Renal Allograft Recipients.
... Similarly in a retrospective study, Haririan et al evaluated the predictive value of mean uric acid in the initial 6 months after transplant for graft function and survival. They recruited 212 live donor renal ...
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