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Renal Denervation

Efficiency and safety of renal denervation via cryoablation (Cryo RDN) in Chinese patients with uncontrolled hypertension: study protocol for a randomized controlled trial

Efficiency and safety of renal denervation via cryoablation (Cryo RDN) in Chinese patients with uncontrolled hypertension: study protocol for a randomized controlled trial

... In 2009, Krum et al. provided the first report showing that renal denervation (RDN) was suitable for treating resistant hypertension [4]. In the last decade, there have been numerous RDN studies conducted ...

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Renal denervation promotes atherosclerosis in hypertensive apolipoprotein e-deficient mice infused with angiotensin II

Renal denervation promotes atherosclerosis in hypertensive apolipoprotein e-deficient mice infused with angiotensin II

... Mice were euthanized after infusion with angiotensin II for 28 days, and the thoracic aortic was used for RNA extraction. mRNA expression was analyzed using quantitative PCR. The relative gene expression was normalized ...

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Renal sympathetic nerve activity after catheter-based renal denervation

Renal sympathetic nerve activity after catheter-based renal denervation

... For reference, we used data of five patients (aged 39– 66 years) in whom 123 I–m IBG was performed of the kid- ney allograft after recent kidney transplantation (0.1 to 1.5 years after transplantation), whose detailed ...

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Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II- induced hypertension

Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II- induced hypertension

... Renal denervation (RDN) by ablation of renal sympathetic nerves was utilized as a potential treatment for patients with resistant hypertension ...and denervation-treated patients [8], recent ...

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Renal denervation in an animal model of diabetes and hypertension: Impact on the autonomic nervous system and nephropathy

Renal denervation in an animal model of diabetes and hypertension: Impact on the autonomic nervous system and nephropathy

... of renal denervation on nephropathy development mechanisms (blood pressure, cardiovascular autonomic changes, renal GLUT2) in diabetic-hypertensive ...surgical renal denervation (RD) or ...

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Changes in glomerular hemodynamic response to angiotensin II after subacute renal denervation in rats

Changes in glomerular hemodynamic response to angiotensin II after subacute renal denervation in rats

... (measured kidney) 4-6 d prior to the measurement periods. Measurements of glomerular dynamics were performed in a control period after plasma volume expansion and during infusion of 11 ng X 100 g body wt-1 X min-1 of ...

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Joint UK societies’ 2019 consensus statement on renal denervation

Joint UK societies’ 2019 consensus statement on renal denervation

... Endovascular renal denervation (RDN) appears to hold some promise as a non-pharmacological approach to lowering BP and achieves renal sympathectomy using either radiofrequency energy or ...

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The effects of acute renal denervation on kidney perfusion and metabolism in experimental septic shock

The effects of acute renal denervation on kidney perfusion and metabolism in experimental septic shock

... Renal denervation effectively increased RBF and cortical perfusion during early, normotensive sepsis whereas medullary flow was unaffected. The increase in RBF was transient and, after hypotension, values ...

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The effect of a thermal renal denervation cycle on the mechanical properties of the arterial wall

The effect of a thermal renal denervation cycle on the mechanical properties of the arterial wall

... during renal denerva- tion procedures that use temperatures in the range of 70 1 ...a renal denervation thermal cycle, as it contains signi fi cant amounts of collagen — the main structural ...thermal ...

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Effects of acute unilateral renal denervation in the rat

Effects of acute unilateral renal denervation in the rat

... the renal responses to acute unilateral renal denervation and the mechanisms involved in these ...responses. Denervation was produced in anesthetized nondiuretic rats by application of phenol ...

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Renal denervation and blood pressure reduction in resistant hypertension: a systematic review and meta-analysis

Renal denervation and blood pressure reduction in resistant hypertension: a systematic review and meta-analysis

... following renal denervation was between 25 and 30 mm Hg for of fi ce blood pressure measurements while on 24 h ambulatory monitoring, it was approximately 10 mm ...unblinded denervation studies, such ...

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Resistant hypertension: Renal denervation or pharmacovigilance? Insights from a renal denervation screening program

Resistant hypertension: Renal denervation or pharmacovigilance? Insights from a renal denervation screening program

... potensive effect of RDN was still present 36 months from the date of the procedure. Blood pressure measurements were on average 32 mm Hg lower for systolic BP and 14.4 mm Hg lower for diastolic BP as compared to the  ...

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Renal denervation decreases effective refractory period but not inducibility of ventricular fibrillation in a healthy porcine biomodel: a case control study

Renal denervation decreases effective refractory period but not inducibility of ventricular fibrillation in a healthy porcine biomodel: a case control study

... sympathetic denervation) reduces the rate of cardiac events refractory to therapy in most patients with inherited arrhythmia syndromes, such as long-QT syndrome and cathecholaminergic polymorphic ventricular ...

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The cholinergic anti-inflammatory pathway in resistant hypertension treated with renal denervation

The cholinergic anti-inflammatory pathway in resistant hypertension treated with renal denervation

... RDN: Renal Denervation; RMSSD: Square root of the mean of the sum of the squares of differences between adjacent NN intervals; SDNN: Standard Deviation of all RR intervals; TNF: Tumor Necrosis Factor; WBC: ...

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The effect of renal denervation in an experimental model of chronic renal insufficiency, The REmnant kidney Denervation In Pigs study (REDIP study)

The effect of renal denervation in an experimental model of chronic renal insufficiency, The REmnant kidney Denervation In Pigs study (REDIP study)

... Background: Renal denervation (RDN) is a promising therapeutic method in ...chronic renal insufficiency among ...with renal insufficiency and resistant hypertension are proposed to be a good ...

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Renal denervation for the management of resistant hypertension

Renal denervation for the management of resistant hypertension

... Abstract: Renal sympathetic denervation (RSD) as a therapy for patients with resistant hypertension has attracted great ...of renal denervation in the management of hypertension will be ...

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The effect of continuous positive airway pressure (CPAP) on renal vascular resistance: the influence of renal denervation

The effect of continuous positive airway pressure (CPAP) on renal vascular resistance: the influence of renal denervation

... impaired renal function [2,3] and PEEP is known to reduce urinary output and sodium excretion ...Reduced renal blood flow has been implicated as a possi- ble mechanism for the development of fluid retention ...

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Treating resistant hypertension: role of renal denervation

Treating resistant hypertension: role of renal denervation

... disease, renal artery stenosis, or obstructive sleep ...increasing renal renin release, decreasing renal blood flow, and enhancing tubular sodium ...Catheter-based renal denervation ...

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Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE deficient rats

Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE deficient rats

... Renal denervation (RDN) has been shown to reduce blood pressure (BP) in animal models and in cer- tain patients with uncontrolled hypertension [9–12]. Recent studies have demonstrated that RDN may also ...

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Original Article Therapeutic effect and prognostic life quality of renal denervation therapy and nifedipine combined with metoprolol tartrate in the treatment of resistant hypertension

Original Article Therapeutic effect and prognostic life quality of renal denervation therapy and nifedipine combined with metoprolol tartrate in the treatment of resistant hypertension

... [18] Fadl Elmula FE, Jin Y, Yang WY, Thijs L, Lu YC, Larstorp AC, Persu A, Sapoval M, Rosa J, Wi- dimský P, Jacobs L, Renkin J, Petrák O, Chatel- lier G, Shimada K, Widimský J, Kario K, Azizi M, Kjeldsen SE and Staessen ...

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