Renin secretion
Cellular control of renin secretion
... of renin secretion have been reported for atrial natriuretic ...of renin secretion from isolated perfused kidneys, from kidney slices or from isolated JGE cells has been reported (Kurtz et ...
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Role of cGMP kinase II in the control of renin secretion and renin expression
... the renin system, we studied the regulation of renin in cGKI- or cGKII-deficient mice in vivo and in ...Renal renin mRNA levels both un- der stimulatory (low-salt diet plus ramipril) and inhibitory ...
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Response of plasma prorenin and active renin to chronic and acute alterations of renin secretion in normal humans Studies using a direct immunoradiometric assay
... active renin and prorenin in physiologic and pharmacologic studies designed to characterize renin biosynthesis and processing in response to both chronic and acute stimuli of renin secretion ...
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Endothelial cells modulate renin secretion from isolated mouse juxtaglomerular cells
... on renin secretion from renal juxtaglomerular ...stimulated renin release were markedly ...on renin secretion was not altered by endothelial cells, whereas the stimulatory effect of ...
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Mechanisms of portal hypertension induced alterations in renal hemodynamics, renal water excretion, and renin secretion
... innervated kidneys. No significant change in either GFR or RBF and a decrease in renin secretion occurred with increases in PVP in denervated kidneys. To dissociate the changes in cardiac output and mean ...
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Presence of renin secretory granules in rat adrenal gland and stimulation of renin secretion by angiotensin II but not by adrenocorticotropin
... adrenal renin. By differential centrifugation of adrenal capsules, we found renin mainly in mitochondrial ...The renin activity in the dense granules from the capsules of nephrectomized rats was 15 ...
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Uterine blood flow and uterine renin secretion
... relationship between uterine blood flow and uterine renin secretion. Uterine blood flow was measured by the percentage distribution of radioactive microspheres injected into the left ventricle which lodged ...
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Involvement of endothelium derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney
... average renin secretion rates from ...of renin secretion in response to a reduction of the renal artery pressure was markedly attenuated with inhibitors of EDRF formation such as ...
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Calcitonin gene related peptide is a stimulator of renin secretion
... stimulate renin secretion in vivo in normal human ...of renin in vitro from isolated rat renal juxtaglomerular cells (half-maximal effective concentration [EC50] 100 nM) concomitant with stimulation ...
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Connexin43 dependent mechanism modulates renin secretion and hypertension
... Plasma renin activity was increased in hypertensive but not in normo- tensive KI32 ...plasma renin activity of the hypertensive, WT 2K1C mice (white bar) was high- er than that of the normotensive ...
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Mechanisms of Renin Secretion during Hemorrhage in the Dog
... in renin release during HH was not abolished by any single maneuver alone including beta adrenergic blockade with d,l-propranolol (n = 6), renal PG inhibition with indomethacin (n = 7), or control of RPP (n = ...
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Potassium balance and the control of renin secretion
... Plasma renin activity and renin substrate were measured in nine groups of rats which were maintained for 7 wk on diets in which the proportions of sodium and potassium were ...plasma renin activity. ...
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Regulation of prorenin secretion in cultured human transfected juxtaglomerular cells
... human renin production (Pinet, ...the renin species secreted was prorenin, and therefore this study concerned primarily prorenin ...secretion. Renin production was stable, since the cells had ...
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Dissociation of systemic and renal effects in endotoxemia Prostaglandin inhibition uncovers an important role of renal nerves
... indomethacin (10 mg/kg i.v.) or meclofenamate (5 mg/kg i.v.). A third group of dogs (Group III, n = 5) received indomethacin (10 mg/kg i.v.) only. 1 h after E group I dogs, mean arterial pressure (MAP) decreased from 126 ...
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The effect of sodium nitrite infusion on renal function, brachial and central blood pressure during enzyme inhibition by allopurinol, enalapril or acetazolamide in healthy subjects: a randomized, double-blinded, placebo-controlled, crossover study
... on renin secretion, while most in vivo studies agree on a stimulatory effect ...of renin secretion after sys- temic NO inhibition in healthy subjects with activated renin system at ...
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Renin Inhibitor: An Overview
... aldosterone secretion, renal sodium reabsorption, sympathetic neurotransmission, and cellular ...The renin system can be inhibited at various points β blockers reduce the release of renin from the ...
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Effect of beta adrenergic blockade on renin response to renal nerve stimulation
... block renin secretion in response to various extrarenal stimuli, such as hemorrhage and hypoglycemia, has been interpreted to indicate the presence of an intrarenal beta receptor regulating renin ...
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The Relationship between Aldosterone to Renin Ratio and RI Value of the Uterine Artery in the Preeclamptic Patient vs Normal Pregnancy
... that renin secretion is suppressed in hypertensive pregnancies whlile aldosterone production is maintained but not totally related to the rennin secretion due to an increased availability of ...
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An effect of extrarenal beta adrenergic stimulation on the release of renin
... isoproterenol, increases plasma renin activity (PRA) by activation of intrarenal or extrarenal pathways. The effects of intravenous (i.v.) and renal arterial infusion of isoproterenol on PRA and renin ...
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A Polymorphism of the Renin Gene rs6682082 Is Associated with Essential Hypertension Risk and Blood Pressure Levels in Korean Women
... Our study has a few limitations. First, the statistical power of this study was limited due to the restricted sample size. Second, promoter activity was not supported with endoge- nous plasma renin levels. ...
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