repeated injections
High Incidence of Scrapie Induced by Repeated Injections of Subinfectious Prion Doses
... to repeated injections of low doses of ...cutaneous injections (7, ...that repeated injections of subinfectious prion doses might cause the devel- opment of transmissible spongiform ...
5
Accelerated drug release and clearance of PEGylated epirubicin liposomes following repeated injections: a new challenge for sequential low-dose chemotherapy
... low-dose injections have the advantage of producing lower side effects and attenuated multidrug ...Although repeated low-dose chemotherapy of liposomes has many potential advantages, it may also have the ...
12
VALIDATED HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS ESTIMATION OF MAGALDRATE AND SIMETHICONE IN API AND TABLET DOSAGE FORM AND ITS APPLICATION TO FORCED DEGRADATION STUDIES
... six repeated injections of standard and sample solutions were made and the response factor of drug and percentage RSD were ...six repeated injections of standard and sample solutions were made ...
6
NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage
... antioxidant genes, SOD2/catalase, PGC1a, and NRF2 in murine models of an inherited retinal degeneration disease, retinitis pig- mentosa (RP), as well as in a model of nerve crush damage. The key neuronal cell type that ...
14
The albumin-exendin-4 recombinant protein E2HSA improves glycemic control and β-cell function in spontaneous diabetic KKAy mice
... Repeated injections with E2HSA in diabetic KKAy mice The spontaneous diabetic KKAy mice were grouped based on the fasting blood glucose, TG, TC and body weight (n = ...
9
Increasing lean muscle mass in mice via nanoparticle-mediated hepatic delivery of follistatin mRNA
... Results: Animal studies validated that mRNA-loaded nanoparticles enter systemic circulation following subcutaneous injection, accumulate and internalize in the liver, where the mRNA is translated into follistatin. ...
13
Neutralizing antibodies to botulinum neurotoxin type A in aesthetic medicine: five case reports
... neurotoxin injections are a valuable treatment modality for many therapeutic indications as well as in the aesthetic field for facial ...requires repeated injections over a long period of time, ...
7
RP HPLC Method for Simultaneous Estimation of Paracetamol and Etoricoxib from Bulk and Tablets
... 3 repeated injections of standard and sample solutions were made in a day and the response factor of drug peaks and percentage RSD were calculated and presented in Table ...3 repeated ...
7
Pharmacodynamics of cisatracurium in the intensive care unit: an observational study
... In all patients, (elective surgical patients as well as the ICU patients) general anesthesia was induced with propofol (2.5 to 3 mg.kg -1 ) and sufentanil (0.1 to 0.2 mg.kg -1 ) and an initial bolus of cisatracurium at a ...
5
CHLORAMPHENICOL (CHLOROMYCETIN), AN ANTIBIOTIC PHARMACOLOGICAL AND PATHOLOGICAL STUDIES IN ANIMALS
... Analogous volumes of propylene glycol alone caused 5 to 10 per cent fall in blood pressure on repeated injections in the same animal and none when given in single doses to different anim[r] ...
11
Study of Renal Toxicity in Wistar Rats Following the Action of Amphotericin B Solution Prepared under Extreme pH Conditions
... to repeated injections for 48 hours until the animal ...three injections of AmB solubilized 10 –4 M so- lutions in acetate/acetic acid (100 mM) of pH buffer ...
5
Repeated intravitreal injections of antivascular endothelial growth factor in patients with neovascular age-related macular degeneration may increase the risk of ischemic optic neuropathy
... Previous studies have shown that VEGF plays a role in modulating both vascular tone and blood flow autoregu- lation [30]. Ameri et al. found that a sudden decrease in the effective VEGF concentration might be responsible ...
7
Monoclonal Anti-HMGB1 (High Mobility Group Box Chromosomal Protein 1) Antibody Protection in Two Experimental Arthritis Models
... of repeated injections of this antibody have now been studied in two conceptually different models of arthritis: collagen type II–induced arthritis (CIA) in DBA/1 mice and in a spontaneous arthritis disease ...
6
Sarah_Langston_Thesis_Final_Copy.pdf
... imiquimod injections; however, this increase was observed in the female imiquimod group after the first injection while imiquimod males showed this increase after repeated ...third injections, which ...
22
Repeated autologous intraarticular blood injections as an animal model for joint pain in haemophilic arthropathy
... behaviour, repeated injections resulted in signifi- cant and sustained primary hyperalgesia and an increase in guarding, as well as a trend for weight bearing alter- ...multiple injections. ...
10
STUDIES IN THE PHYSIOLOGY OF SWEATING IN CYSTIC FIBROSIS
... Two types of experimental sweat gland fatigue with repeated injections of methacholine, and the observed frequencies in patients with cystic. fibrosis and in controls[r] ...
11
Repeated TLR9 stimulation results in macrophage activation syndrome–like disease in mice
... As in the MAS syndrome, CpG-treated mice developed elevated serum ferritin (Figure 1E) after 10 days of treatment. Patients with MAS also develop a disseminated intravascular coagulopathy (DIC) (14–17), usually assessed ...
15
<p>Incidence of Glaucoma or Ocular Hypertension After Repeated Anti-Vascular Endothelial Growth Factor Injections for Macular Degeneration</p>
... (TA) injections, where TA crystals were observed in the anterior chamber 1 hr after injection in 5 of 31 pseudophakic patients, but no anterior chamber crystals were observed at this time point in the 57 phakic ...
10
Epimacular brachytherapy for wet AMD: current perspectives
... The pathophysiology of wet AMD is complex and is not fully understood. Although anti-VEGF therapy has proven very successful, it is not effective for all patients, and the recommended therapy involves expensive monthly ...
10
α7 Nicotinic acetylcholine receptor-mediated anti-inflammatory effect in a chronic migraine rat model via the attenuation of glial cell activation
... Materials and methods: Thirty-six male Sprague–Dawley rats were distributed randomly into control, CM, PNU-282987, and α-bungarotoxin groups (n=9 rats in each group). The CM model was established by the recurrent daily ...
12