Requirements for cilia formation and function
Hash function requirements for Schnorr signatures
... Abstract. We provide two necessary conditions on hash functions for the Schnorr signature scheme to be secure, assuming compact group representations such as those which occur in elliptic curve groups. We also show, via ...
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C2cd3 is required for cilia formation and Hedgehog signaling in mouse
... Gli3. Cilia biogenesis is severely disrupted in the absence of ...of cilia, mediates calcium-dependent vesicular transport and/or recruitment of proteins, including Hh pathway components, during ...
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Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1
... and cilia length (Suizu et ...promoted cilia loss without determining the effect on cilia length (Conduit et ...characterized function of pVHL (the product of VHL gene) is to act as a ...
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Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation
... mary cilia next to the basal body in mammalian ciliated cells ( 38 ...another function previously associated to SDOS ( 2 , 3 ), are also co- ordinated by primary cilia, such as Hh, TGF  and RTK ...
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The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation
... moving intrinsically more slowly but instead spending more time at rest. This pausing might be explained by the slower rate of microtubule re-growth observed in talpid 3 mutant cells. We have identified a region of the ...
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Requirements for Hirano Body Formation
... body formation, since the size of model Hirano bodies formed in the presence of blebbistatin grew more slowly than that of the control ...the formation of Hirano ...a function by cross-linking actin ...
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Cilia, Wnt signaling, and the cytoskeleton
... and function is in turn necessary for cilia formation or func- ...the cilia-related proteins are now being identified in other cellular locations and could possibly be required for additional ...
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Cilia in the developing zebrafish ear
... Abstract The inner ear, which mediates the senses of hearing and balance, derives from a simple ectodermal vesicle in the vertebrate embryo. In the zebrafish, the otic placode and vesicle express a whole suite of genes ...
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Motile and non-motile cilia in human pathology: from function to phenotypes
... of cilia in human health and disease and discuss a growing shift away from the classical clinical definitions of ciliopathy syndromes to a more functional ...
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Cilia-mediated Hedgehog signaling controls form and function in the mammalian larynx
... and function in the vocal apparatus is thus an important challenge with relevance both to the basic biology of animal communication and to ...in cilia-mediated Hedgehog ...and function in the ...
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SPEN, a new player in primary cilia formation and cell migration in breast cancer
... primary cilia formation, we also report that SPEN coordinates migration in breast epithelial cells, but only in those that are ...primary cilia abundance, suggesting that SPEN may control migration ...
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Primary defects in the structure and function of sensory and motile cilia result in multiple ciliopathies
... The movement of chromosomes during mitosis occurs on a bipolar, microtubule-based protein machine, the mitotic spindle. It has long been proposed that pole ward chromosome movements that occur during prometaphase and ...
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The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle
... (tether cilia) at the otic vesicle poles, forming two ...of cilia and ciliary motility in otolith ...motile cilia are present at the otic vesicle poles, surrounding the immotile tether ...motile ...
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Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts
... identified cilia in rod photoreceptors and cholangiocytes in fixed mouse tissues and examined the structures that these cilia contact in ...that cilia from nearby cells touch one ...the ...
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CILIA: before and after
... bend formation, dyneins on one set of doublet MTs are active, while an opposing set are inactive, and this reverses for an opposing part of the beat (recovery bend formation) ...
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Cilia in autophagy and cancer
... between cilia and autophagy is emerging as a new field for future stud- ...on/off cilia formation by alternatively degrading ciliary essential protein, IFT20, or suppressive protein, ...tiation, ...
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CiteSeerX — ecosystems: formation, function, and stability
... tegrate function and diversity, and that are dynam- ical, 13 since at present many of the current models for soil are ...the function- ality and the dynamical behavior of the soil ...
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Vascular nitric oxide: formation and function
... cell function and ...complex formation results in NO synthesis rates proportional to the O 2 concentration throughout the physiological range due primarily to NOS–NO complex dissociation, which itself is a ...
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The formation and evolution of galaxies as a function of environment
... CMR in rest-frame U − V is small (hσ int i = 0.076). However, there is a small minority of faint early-type galaxies (7%) that are significantly bluer than the CMR and these were excluded from the scatter analysis. ...
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Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer’s disease by regulating cilia function
... primary cilia and cognition, indicating that 5-HT6 may affect cognition through the primary ...respiratory cilia, showed significant behavioral and social competence problems ...primary cilia [30]. ...
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