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RESPONSE REGULATOR

The Response Regulator BfmR Is a Potential Drug Target for Acinetobacter baumannii

The Response Regulator BfmR Is a Potential Drug Target for Acinetobacter baumannii

... AB307.70 is an isogenic BfmR-minus derivative of AB307-0294 generated by transposon mutagenesis, and it possesses a disruption in bfmR (nucleotides 1 to 717) due to the transposon insertion after nucleotide 592. bfmR ...

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A cell wall damage response mediated by a sensor kinase/response regulator pair enables beta-lactam tolerance

A cell wall damage response mediated by a sensor kinase/response regulator pair enables beta-lactam tolerance

... and regulator) for reasons elaborated ...a response regulator (RR) in the OmpR family ...a regulator of type VI secretion (20), but is otherwise ...

7

A Single Domain Response Regulator Functions as an Integrating Hub To Coordinate General Stress Response and Development in Alphaproteobacteria

A Single Domain Response Regulator Functions as an Integrating Hub To Coordinate General Stress Response and Development in Alphaproteobacteria

... in response to specific stimuli, phosphorylates the PhyR response regulator (25, ...stress response activation, suggesting that in an ΔmrrA strain PhyK lacks residual kinase ...stress ...

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Crystallization of the regulatory and effector domains of the key sporulation response regulator Spo0A

Crystallization of the regulatory and effector domains of the key sporulation response regulator Spo0A

... A search for heavy-metal derivatives of crystals of both the functional domains of Spo0A is now under way. In the absence of suitable crystals of the intact protein, we hope that the structures of the two domains of ...

7

Structural Basis for DNA Recognition by the Two Component Response Regulator RcsB

Structural Basis for DNA Recognition by the Two Component Response Regulator RcsB

... Alternative mechanism of transcriptional regulation by RcsB. One of the fea- tures of our crystal structures is that RcsB forms an asymmetric dimer that is identical in two different crystal forms. In one structure, ...

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General Stress Response Regulator RpoS in Adaptive Mutation and Amplification in Escherichia coli

General Stress Response Regulator RpoS in Adaptive Mutation and Amplification in Escherichia coli

... (Hastings et al. 2000). We suggest that point mutation facilitates stationary-phase mutation in this system (Har- occurs in a transiently hypermutable cell subpopulation ris et al. 1997, 1999; and perhaps amplification, ...

12

The Role of the Unfolded Protein Response Regulator Bip in Hcmv Virion Assembly and Egress

The Role of the Unfolded Protein Response Regulator Bip in Hcmv Virion Assembly and Egress

... Human cytomegalovirus (HCMV) regulates the unfolded protein response, including specifically inducing the ER chaperone BiP. The increase in BiP protein during infection is the result of promoter activation by the ...

176

The role of bacterial antizyme: From an inhibitory protein to AtoC transcriptional regulator

The role of bacterial antizyme: From an inhibitory protein to AtoC transcriptional regulator

... has been reported for the NtrC response regulator [63- 67]]. Thereafter, AtoC is probably oligomerized, a process that triggers its ATPase activity (our unpublished data). Upon ATP hydrolysis, the ...

9

Two component signal transduction system CBO0787/
CBO0786 represses transcription from botulinum
neurotoxin promoters in Clostridium botulinum ATCC
3502

Two component signal transduction system CBO0787/ CBO0786 represses transcription from botulinum neurotoxin promoters in Clostridium botulinum ATCC 3502

... cognate response regulator and its subsequent effects on target gene ...TCS response regulators showing similar DNA- binding properties regardless of phosphorylation state [43], in vivo ...

11

Subcellular Localization in Bacteria: From EnvZ/OmpR to Transertion

Subcellular Localization in Bacteria: From EnvZ/OmpR to Transertion

... the response regulator, is phosphorylated by EnvZ in response to signal, the presence of phophorylation dependent OmpR-GFP foci suggested that the active form of OmpR interacted preferentially with ...

114

Histidine phosphorylation in bacterial chemotaxis

Histidine phosphorylation in bacterial chemotaxis

... Mourey, L., et al., Crystal Structure of the CheA Histidine Phosphotransfer Domain that Mediates Response Regulator Phosphorylation in Bacterial Chemotaxis. The Journal of Biological [r] ...

209

Comparative genomics reveals a widespread distribution of an exopolysaccharide biosynthesis gene cluster among Vibrionaceae

Comparative genomics reveals a widespread distribution of an exopolysaccharide biosynthesis gene cluster among Vibrionaceae

... Between D and F genes, additional individual genes or a group of three genes were found in several of the stud- ied Vibrionaceae (Fig. 2a). One of these proteins (E) is homologous to A. fischeri SypE which is a ...

7

Organizational Accessibility and Community Connections: Examining Changes in the Spatial Proximity of Pubic Housing Residents to Social Service Providers and Providers' Responses to Redevelopment

Organizational Accessibility and Community Connections: Examining Changes in the Spatial Proximity of Pubic Housing Residents to Social Service Providers and Providers' Responses to Redevelopment

... GAS adaptation to the human environment relies on complex and cross-interacting regulatory circuits, which interpret diverse environmental signals and produce a dynamic expression profile that is adjusted to the nature ...

140

Cytokinin signaling in plant development

Cytokinin signaling in plant development

... a response regulator that propagates the signal, often by directly regulating the transcription of target ...separate response regulators (RRs) (Appleby et ...

7

Microbiology The Essential WalK Histidine Kinase and WalR Regulator Differentially Mediate Autolysis of Staphylococcus aureus RN4220

Microbiology The Essential WalK Histidine Kinase and WalR Regulator Differentially Mediate Autolysis of Staphylococcus aureus RN4220

... Both the WalR response regulator and the WalK histidine kinase are necessary for growth of S. aureus RN4220. Using a temperature sensitive mutagenesis, it has been revealed that WalRK is required for ...

5

Fur Is the Master Regulator of the Extraintestinal Pathogenic Escherichia coli Response to Serum

Fur Is the Master Regulator of the Extraintestinal Pathogenic Escherichia coli Response to Serum

... their response to serum, making a clear distinction between the responses to nu- tritional immunity and innate ...metabolic response is coordinated by three transcriptional regulators, Fur, BasR, and ...

12

Mitochondrial Two-Component Signaling Systems in Candida albicans

Mitochondrial Two-Component Signaling Systems in Candida albicans

... stress response was demonstrated in an earlier study, in which it was shown that the Ssk1 response regulator protein is FIG 7 Apoptosis measurements in strains of ...

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Copper Response Element and Crr1-Dependent Ni2+-Responsive Promoter for Induced, Reversible Gene Expression in Chlamydomonas reinhardtii

Copper Response Element and Crr1-Dependent Ni2+-Responsive Promoter for Induced, Reversible Gene Expression in Chlamydomonas reinhardtii

... copper response elements (CuREs) and a copper response regulator defined by the CRR1 ...The response to nickel ions requires at least one CuRE and also CRR1 function, suggesting that nickel ...

8

Structural Characterization of Two-Component Signal Transduction Proteins and Calbindin D28k

Structural Characterization of Two-Component Signal Transduction Proteins and Calbindin D28k

... lation response regulator Spo0F was studied using a variety of biophysical and biochemical ...of response regulators from ...the response regulator regulatory domain that is known to ...

198

Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

... response to LPS; however, constitutively, there was no difference in the expression between the genotypes (Supplemental Figure 2B). Elevated expression of CD14 has been associated with increased inflam- mation; ...

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