Results using simulated genotypes and phenotypes
GPA-MDS: A Visualization Approach to Investigate Genetic Architecture among Phenotypes Using GWAS Results
... lipid-related phenotypes (HDL, LDL, TC, and TG) cluster together, blood pressure phenotypes (SBP and DBP) cluster, and so ...These results show the poten- tial of the proposed GPA-MDS approach for ...
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GPA-MDS: A Visualization Approach to Investigate Genetic Architecture among Phenotypes Using GWAS Results
... Currently, we are working on the following directions that can further improve the GPA-MDS framework. First, in this paper, we used a definition of distance based on the logarithm transformation of đť‘ť-values. While this ...
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Genotypes and phenotypes of resistance in Ecuadorian Plasmodium falciparum
... The results showed that PfMDR1 of ESM-2013 is not completely functional, since there was inhibition of Fluo 4 trans- ...These results are not directly related with the cur- rent treatment for ...
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Genotypes and phenotypes of patients with Lafora disease living in Germany
... Methods: The patients described in this case series initially had the suspected clinical diagnosis of Lafora disease, or unclassified progressive myoclonus epilepsy. Molecular genetic diagnostics including next ...
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Genotypes And Phenotypes Of Staphylococci On Selected Dairy Farms In Vermont
... comparing results between studies. Overall, the common method in literature for determining the cut point ODc (Optical density) is mean OD for blank well plus 3 standard deviation (Christensen et al., 1985, ...
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Asthma Phenotypes in Japanese Adults - Their Associations with the CCL5 ADRB2 Genotypes
... The results of re- cent studies on defining asthma phenotypes by use of exploratory methods such as a clustering approach are consistent with observations from clinical prac- tice, showing the importance of ...
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Mucopolysaccharidosis type VI phenotypes-genotypes and antibody response to galsulfase
... Results Patients We describe 12 patients with mucopolysaccharidosis type VI in 10 unrelated families (Table 1). Five of the twelve patients had a rapidly progressive phenotype and presented before the age of 5 ...
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Characteristic cardiac phenotypes are detected by cardiovascular magnetic resonance in patients with different clinical phenotypes and genotypes of mitochondrial myopathy
... Pathological CMR findings indicating cardiac involvement were detected significantly more often than pathological ECG results or elevated cardiac serum biomarkers (34 (53 %) vs. 18 (28 %) vs. 21 (33 %); p = ...
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Novel genotypes and phenotypes among Chinese patients with Floating-Harbor syndrome
... Results: Five distinct pathogenic/likely pathogenic variants were identified in 12 independent FHS patients including two previously reported variants (c.7303C > T/p.Arg2435Ter and c.7330C > T/p.Arg2444Ter) and ...
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Gender, but Not CYP2C19 Genotypes and CYP3A Phenotypes, is a Major Determinant of Ilaprazole Pharmacokinetic
... ilaprazole metabolism, but until recently, no similar discovery had been made in vivo. Two studies have investigated the effect of CYP3A5*3 on kinetics profile of ilaprazole in vivo, however no relationship had been ...
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From integrative genomics to systems genetics in the rat to link genotypes to phenotypes.
... example, using mice, Farber et ...mouse results were translated and integrated with human BMD GWAS ...reconstructed using genome-wide expression analysis of surgically resected hippocampi from ...
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Precision medicine and phenotypes, endotypes, genotypes, regiotypes, and theratypes of allergic diseases
... (82). Unlike β2AR-mediated bronchodilation, T2R function is not impaired in asthma and shows little tachyphylaxis. When stimu- lated by the bacterial acyl-homoserine lactones, T2Rs on ASM may act to open airways and, ...
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Comparison of Cyanobacteria Phenotypes with Distinctive Photosynthetic Pigment Compositions to Simulated Lake Browning
... When no one else believed in me, you gave me a chance. Without this opportunity, my life would have taken a path that I never wanted. I always think back to the time you said, “you shouldn’t do the work of a lab ...
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Characterization of Mycobacterium tuberculosis isolates from Hebei, China: genotypes and drug susceptibility phenotypes
... strains using the L-J proportion method. Results: Based on the ...%). Using 15-locus MIRU-VNTR clustering analysis, 846 different patterns were identified, including 84 clusters (2 – 17 strains per ...
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Ecological and functional biodiversity in a marine algal-virus system: genotypes, phenotypes and their ecological significance
... The results here provide further evidence that, the often ignored, intra-family biodiversity could have real and measurable impact on community and ecosystem composition of ecologically important groups of marine ...
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Using ontologies to describe mouse phenotypes
... these results may be interpreted to indicate a value corresponding to the phenotypic character comprised by the entity 'memory' that was assayed for the attribute of 'short-term recall' and returned the ...
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Rh blood group system phenotypes, haplotypes and probable genotypes among major sudanese tribes
... the results recorded. Results are interpreted as follows: positive= agglutinated cells forming a red line on the surface of the gel or agglutinates dispersed in gel; ...
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The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and phenotypes
... query results page provides summary data and relevant links including allele name, parental zygosity, mutation type, affected gene, mapping position and curated ...
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Genotypes and phenotypes of Shiga toxin-producing <em>Escherichia coli</em> (STEC) in Abeokuta, Southwestern Nigeria
... The prevalence of STEC has led to high mortality rates, mostly in poorly developed regions in Nigeria. 19 It largely occurs via the fecal–oral route and usually results in symp- toms ranging from mild ...
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Call for proposals. Green Genetics. Designing genotypes, improving phenotypes. A STW TKI-U/Plantum Programme
... research results is always on the meeting ...The results of the project are confidential until STW decides otherwise, or until STW has given permission for ...of results by any means, such as a text ...
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