retinal ganglion cell
Visual contrast detection cannot be predicted from surrogate measures of retinal ganglion cell number and sampling density in healthy young adults
... of retinal ganglion cell ...of retinal ganglion cells may have the functional consequence of steeper psychometric functions (smaller spread parameter) due to greater signal in response ...
10
Diagnostic performance of isolated-check visual evoked potential versus retinal ganglion cell-inner plexiform layer analysis in early primary open-angle glaucoma
... GCILP: Retinal ganglion cell-inner plexiform layer; icVEP: Isolated-check visual evoked potential; IOP: Intraocular pressure; OCT: Optical coherence tomography; RGC: Retinal ganglion ...
7
Semaphorin 3d guides laterality of retinal ganglion cell projections in zebrafish
... which retinal ganglion cell (RGC) axons either cross the midline to innervate the contralateral brain or turn back to innervate the ipsilateral ...
10
Neurotrophic regulation of retinal ganglion cell synaptic connectivity: from axons and dendrites to synapses
... to retinal- and tectal-derived BDNF (Lom et al. , 2002). While retinal BDNF reduces RGC dendritic arborization, tectal BDNF stimulates RGC dendritic ...and retinal-derived BDNF to modulate the ...
10
Microglial dynamics after axotomy-induced retinal ganglion cell death
... the retinal regions where there is, proportionally, more RGC ...of cell bodies to be removed, and upon them, more or less MCs migrate to the injured zone, having into account that one MC is able to engulf ...
15
Retinal ganglion cell analysis in multiple evanescent white dot syndrome
... MEWDS, with secondary involvement of the RPE and the neurosensory retina [10]. However, the precise loca- tion of the initial MEWDS pathology remains unclear. Due to recent advances in OCT technology, there are now more ...
6
Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons
... of ganglion cells with intact uptake of CTB and a 14-42% reduction in the number of immuno-labelled ganglion cell bodies, with the worst loss occurring ...of ganglion cell axons in ...
14
The Relationship Between the Photopic Negative Response and Retinal Ganglion Cell Topography
... Simplistically, one might expect to find a linear relationship between RGC cell numbers and PhNR amplitude but several lines of evidence suggest this may not be the case. In pharmacologic experiments in macaque to ...
10
GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients
... in retinal Tgfb2 gene expression in the ONC model or the murine chronic glaucoma ...of retinal cells induced by high IOP, and although animal models replicate some features of human POAG, they do not ...
15
Complementation analysis of pseudorabies virus gE and gI mutants in retinal ganglion cell neurotropism.
... Virus infection of circadian centers and visual centersa Presence of viral antigen in: Virus Suprachiasmatic nucleus and intergeniculate leaflet circadian centers PRV-Be PRV91 PRV98 PRV9[r] ...
5
The cell adhesion molecule NrCAM is crucial for growth cone behaviour and pathfinding of retinal ganglion cell axons
... micrograph of a flat-mounted retina (E4) stained for NrCAM. (A) NrCAM is selectively present on RGC axons. Because of the developmental gradient from the central to the peripheral retina, only single axons and thin axon ...
10
The role of retinal ganglion cell axons in the regulation of glial cell numbers in the rodent optic nerve
... I have p rovided four lines of evidence to suggest th at RGC axons drive the proliferation of astrocytes in the developing p o stn atal ro d en t optic nerve. First, I show th at astrocyte proliferation is increased in ...
138
Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5
... amacrine cell fate, and are capable of producing excess numbers of amacrine cells when each of them is ectopically co-expressed with Pax6 or Six3 (Inoue et ...
10
A novel retinal ganglion cell promoter for utility in AAV vectors
... target cell type is often preferable, and in principle represents a valuable safety ...toward retinal ganglion cells (RGCs) using AAV serotype 2, with several ongoing or completed clinical trials ...
12
Retinal ganglion cells : physiology and prosthesis
... Retina, retinal ganglion cell, retinal prosthesis, bionic eye, electrical stimulation, intrinsic property, phase plot, receptive field, brisk-transient, brisk-sustained... Table of Conte[r] ...
199
Endothelial cell derived semaphorin 3A inhibits filopodia formation by blood vascular tip cells
... the retinal ganglion cell layer and the secreted protein binds to Nrp1- and plexin-A1- positive blood ...X-gal-stained retinal whole mount of a P7 Sema3a +/lacZ ...the retinal GCL ...
6
Axonal Transport and Sorting of Herpes Simplex Virus Components in a Mature Mouse Visual System
... mouse retinal ganglion cell axons in ...in retinal homogenates by 2 ...the retinal ganglion cell ...proximal ganglion cell axon by 2 days and reached the ...
10
The retinoprotective role of phenytoin
... effect, retinal ganglion cell survival was considered the pri- mary ...the ganglion cell sur- vival with and without phenytoin gave the following results: optic nerve crush: ...4.0 ...
5
Pupil autoregulation impairment as an early marker of glaucomatous damage
... Patients with diagnosed glaucoma or glaucoma suspects were prospectively enrolled in the study. The included patients were those who were diagnosed with glaucoma and glaucoma suspects who converted to glaucoma within 5 ...
9
Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury
... Background: Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this ...
13