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Retinal pigment epithelial

Altered aldose reductase gene regulation in cultured human retinal pigment epithelial cells

Altered aldose reductase gene regulation in cultured human retinal pigment epithelial cells

... human retinal pigment epithelial cell lines exposed to hyperglycemic and hyperosmolar conditions in ...several retinal pigment epithelial cell ...

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Effects of concentration of amyloid β (Aβ) on viability of cultured retinal pigment epithelial cells

Effects of concentration of amyloid β (Aβ) on viability of cultured retinal pigment epithelial cells

... Our results showed that the number of living RPE cell was significantly increased by exposure to 5 μ M A β but markedly decreased by an exposure to 25 μ M A β . These results indicated that the influence of A β on ...

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Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells

Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells

... Our observations relate to cell-based work on retinal pigment epithelial cells, which might not be principally relevant to an in vivo setting. Impacts of neighboring cells of photoreceptors, in ...

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Effect of curcumin on aging retinal pigment epithelial cells

Effect of curcumin on aging retinal pigment epithelial cells

... Abstract: Age-related macular degeneration (AMD) is now one of the leading causes of blindness in the elderly population. The antioxidative effects of curcumin on aging retinal pigment epithelial ...

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Effects of glucose on sorbitol pathway activation, cellular redox, and metabolism of myo inositol, phosphoinositide, and diacylglycerol in cultured human retinal pigment epithelial cells

Effects of glucose on sorbitol pathway activation, cellular redox, and metabolism of myo inositol, phosphoinositide, and diacylglycerol in cultured human retinal pigment epithelial cells

... expressing retinal pigment epithelial cells, glucose-induced, aldose reductase inhibitor-sensitive CDP- diglyceride accumulation and inhibition of 32P-incorporation into phosphatidylinositol ...

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Effects of steady electric fields on human retinal pigment epithelial cell orientation and migration in culture

Effects of steady electric fields on human retinal pigment epithelial cell orientation and migration in culture

... Low-level, steady electric fields of 6-10 voltskm stimulated directional orientation and translocation of cultured human retinal pigment epithelial cells.. The orientative movements galv[r] ...

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Biocompatibility of the vital dye Acid Violet-17 on retinal pigment epithelial cells

Biocompatibility of the vital dye Acid Violet-17 on retinal pigment epithelial cells

... the retinal pigment epithelial (RPE) cells, and a reduced visual acuity especially after the use of ICG or TB, 3–6 resulting in an increasing concern ...

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Treatment of Retinal Pigment Epithelial Detachment

Treatment of Retinal Pigment Epithelial Detachment

... Anatomical separation of the retinal pigment epithelium (RPE) from the Bruch membrane is de ined as retinal pigment epithelial detachment (PED). Several degenerative and idiopathic ...

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Optimization of an in vitro bilayer model for studying the functional interplay between human primary retinal pigment epithelial and choroidal endothelial cells isolated from donor eyes

Optimization of an in vitro bilayer model for studying the functional interplay between human primary retinal pigment epithelial and choroidal endothelial cells isolated from donor eyes

... primary retinal pigment epithelial cells (hRPE) and human primary choroidal endothelial cells (hCEC) from donor eyes to construct a bilayer of hCEC/hRPE on transwell ...

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Original Article Plasticity of adult human retinal pigment epithelial cells

Original Article Plasticity of adult human retinal pigment epithelial cells

... Retinal pigment epithelium (RPE) cell damage underlies many degenerative, dystrophic, and proliferative diseases of human retina [1, ...for retinal function and they are highly specialized and do not ...

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Osmolarity and spectrophotometric property of brilliant blue green define the degree of toxicity on retinal pigment epithelial cells exposed to surgical endoilluminator

Osmolarity and spectrophotometric property of brilliant blue green define the degree of toxicity on retinal pigment epithelial cells exposed to surgical endoilluminator

... Conclusion: Our findings suggest that BBG at 0.25 mg/mL during vitreoretinal surgery is safe and not toxic to RPE cells up to 5 minutes under focal high illumination (10 mm) and up to 15 minutes under medium diffuse ...

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Original Article Effect of bradykinin on cultured retinal pigment epithelial cells

Original Article Effect of bradykinin on cultured retinal pigment epithelial cells

... In this study, BK was found to promote the expression of COX-2 and iNOS, which are impor- tant inflammatory factors. BK is an important vasoactive substance that might be related to PDR. BK activates NOS expression, ...

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Cyclic stretch induced-retinal pigment epithelial cell apoptosis and cytokine changes

Cyclic stretch induced-retinal pigment epithelial cell apoptosis and cytokine changes

... VMA-induced retinal stretching, by means of medication or surgery, has the potential to protect against the development and progression of AMD, which offers new insights into the prevention and treatment of ...

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Retinal pigment epithelial cells in vitro: Behaviour and the cytoskeleton with particular emphasis on cytokeratins

Retinal pigment epithelial cells in vitro: Behaviour and the cytoskeleton with particular emphasis on cytokeratins

... intestinal epithelial cells (Mooseker & Tilney, 1975; Geiger et al, 1980, 1981; Hirokawa et al, ...all epithelial cells, including the RPE, and of focal adhesion plaques (focal contacts) in cultured ...

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Enhanced generation of retinal progenitor cells from human retinal pigment epithelial cells induced by amniotic fluid

Enhanced generation of retinal progenitor cells from human retinal pigment epithelial cells induced by amniotic fluid

... induce retinal progenitor genes and thus convert an RPE culture into an invaluable source of retinal progenitor ...in epithelial mesenchymal transition (EMT), cell migration to the area of damage and ...

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Influence of Cell Confluency on the Expression of the α4 Integrin Subunit of Retinal Pigment Epithelial Cells

Influence of Cell Confluency on the Expression of the α4 Integrin Subunit of Retinal Pigment Epithelial Cells

... Apart from the immune cells, the α 4 β 1 integrin has also been identified on dermal fibroblasts [27], in the epi- cardium [28] [29], on developing myocytes [30] [31], on neural crest cells [32] [33], on ...

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Expression of microRNA in human retinal pigment epithelial cells following infection with Zaire ebolavirus

Expression of microRNA in human retinal pigment epithelial cells following infection with Zaire ebolavirus

... Abbreviations cDNA: complementary DNA; DNA: deoxyribonucleic acid; EBOV: Zaire ebolavirus; EBV: Epstein–Barr virus; EVD: Ebola virus disease; IFN: interferon; KEGG: Kyoto Encyclopedia of[r] ...

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Original Article Exendin-4 protects retinal pigment epithelial cells against oxidative stress in vitro via PI3K/Akt-STAT3 activation

Original Article Exendin-4 protects retinal pigment epithelial cells against oxidative stress in vitro via PI3K/Akt-STAT3 activation

... sheets of fetal neural retina with its retinal pig- ment epithelium in retinitis pigmentosa pa- tients. Am J Ophthalmol 2002; 133: 544-550. [7] Davidson AE, Millar ID, Urquhart JE, Burgess- Mullan R, Shweikh Y, ...

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Synergistic effects of gamma interferon on inflammatory mediators that induce interleukin-6 gene expression and secretion by human retinal pigment epithelial cells.

Synergistic effects of gamma interferon on inflammatory mediators that induce interleukin-6 gene expression and secretion by human retinal pigment epithelial cells.

... INFLAMMATORY MEDIATORS AND IL-6 SECRETION BY RPE CELLS 577 human retinal pigment epithelium, p. Marmor (ed.), The retinal pigment epithelium[r] ...

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Evaluation of ultraviolet light toxicity on cultured retinal pigment epithelial and retinal ganglion cells

Evaluation of ultraviolet light toxicity on cultured retinal pigment epithelial and retinal ganglion cells

... radiated retinal ganglion and pigment epithelial cells were observed using bright field phase contrast microscopy (Olympus 1 × 51; Long Island, ...

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