RGD motif
The coxsackievirus A9 RGD motif is not essential for virus viability.
... an RGD (arginine-glycine-aspartic acid) motif, located in an exposed position, has been implicated by peptide-blocking studies (2, 4, 12, 38) and mutagenesis (22, ...an RGD motif (8, ...The ...
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Analysis of a conserved RGE/RGD motif in HCV E2 in mediating entry
... RGE/RGD motif of E2, is crit- ical for the proper folding and structure of ...acid motif is the trans- membrane domain, which has been well defined in its involvement in entry ...
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An evolutionary RGD motif in the spike protein of SARS-CoV-2 may serve as a potential high risk factor for virus infection?
... the RGD motif by Hydrogen bonds, and/or π-π/p-π interactions respectively, indicating that these hits may potentially block interaction of S protein with ACE2 and ...
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Integrin αVβ3 Binds to the RGD Motif of Glycoprotein B of Kaposi's Sarcoma-Associated Herpesvirus and Functions as an RGD-Dependent Entry Receptor
... the RGD motifs of viral (B) and extracellular matrix (C) ligands of cellular integrin ...The RGD motif is boxed, and conserved res- idues, including conservative (S)erine–(T)hreonine changes, are ...
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Canine Adenovirus Type 2 Attachment and Internalization: Coxsackievirus-Adenovirus Receptor, Alternative Receptors, and an RGD-Independent Pathway
... an RGD motif. The lack of an RGD motif in the CAV-2 virion suggests that this motif may have a rather limited role in internalization and that other motifs in the CAV-2 capsid probably ...
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Positively Charged Residues at the Five-Fold Symmetry Axis of Cell Culture-Adapted Foot-and-Mouth Disease Virus Permit Novel Receptor Interactions
... (RGD) motif located at the apex of a structurally disordered loop (the GH loop of ...other RGD-dependent integrins ( ␣ v  1, ␣ v  3, and ␣ v  8) have also been reported to be receptors for field ...
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Contrasting Effects of Human, Canine, and Hybrid Adenovirus Vectors on the Phenotypical and Functional Maturation of Human Dendritic Cells: Implications for Clinical Efficacy
... In contrast to the case with Ad  gal, hMoDC incubated with all doses of CAV  gal or AAV vectors (not shown) showed no marked upregulation of costimulatory molecules or MHC class I/II molecules in most donors (Fig. 3A). ...
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Cell Recognition by Foot-and-Mouth Disease Virus That Lacks the RGD Integrin-Binding Motif: Flexibility in Aphthovirus Receptor Usage
... the RGD motif upon replication in cell culture ...the RGD motif (43, ...the RGD motif is conditioned to a number of amino acid replace- ments in the FMDV ...the RGD ...
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Identification of HI-Like Loop in CELO Adenovirus Fiber for Incorporation of Receptor Binding Motifs
... integrin-binding motif (RGD) was incorporated at two different sites of the fiber 1 knob domain, within an HI-like loop that we identified and at the C ...the RGD motif within the HI-like loop ...
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Nonimmune cell–derived ICOS ligand functions as a renoprotective αvβ3 integrin–selective antagonist
... Inducible costimulator ligand (ICOSL) (also known as B7h, GL50, B7RP-1, and B7-H2) belongs to the B7 superfamily of pro- teins that bind to the CD28 family of receptors on lymphocytes (15– 19). ICOSL is expressed ...
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Novel production method of innovative antiangiogenic and antitumor small peptides in <em>Escherichia coli</em>
... cyclic RGD motif, this peptide presents an improved targeting capability of α 5 β 1 and α v β 3 integrins- expressing tumor cells and endothelial ...
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Preparation and evaluation of RGD and TAT co-modified docetaxel-loaded liposome
... Different DTX-LPs were prepared by the emulsification- solvent evaporation method. Briefly, DTX (5 mg), phosphatidylcholine (100 mg), cholesterol (50 mg), and DSPE-PEG1000–TAT (2.5 mg) and DSPE-PEG3500–RGD (2.5 ...
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Optical imaging of head and neck squamous cell carcinoma in vivo using arginine-glycine- aspartic acid peptide conjugated near-infrared quantum dots
... conjugated RGD with quan- tum dots with emission wavelength of 800 nm (QD800) to generate QD800-RGD, and used it via intravenous injection as a probe to image tumors in nude mice bearing head and neck ...
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Stimulating effect of graphene oxide on myogenesis of C2C12 myoblasts on RGD peptide-decorated PLGA nanofiber matrices
... Immunofluorescence staining of C2C12 myoblasts For the morphological observations, C2C12 myoblasts cultured on the PLGA or RGD/PLGA matrices for 3 and 7 days were fixed with a 3.7 % formaldehyde solution ...
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Noninvasive monitoring of early antiangiogenic therapy response in human nasopharyngeal carcinoma xenograft model using MRI with RGD-conjugated ultrasmall superparamagnetic iron oxide nanoparticles
... of RGD-PAA-USPIO with human umbilical vein endothelial cells (HUVECs) was confirmed by Prussian blue staining and transmission electron microscopy in ...of RGD-PAA-USPIO was evaluated in the NPC xenograft ...
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RGD: A comparative genomics platform
... The RGD provides a unique comparative genomics platform for researchers interested in comprehen- sive rat, mouse and human ...make RGD an outstanding resource, not only for rat researchers, but also for ...
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Cell-adhesive RGD peptide-displaying M13 bacteriophage/PLGA nanofiber matrices for growth of fibroblasts
... of RGD-M13 phage/PLGA mat- rices was observed under a scanning electron microscope ...The RGD-M13 phages and nano- fibers were characterized by using Raman ...in RGD-M13 phage/PLGA matrices or not, ...
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Arginine–glycine–aspartic acid–polyethylene glycol–polyamidoamine dendrimer conjugate improves liver-cell aggregation and function in 3-D spheroid culture
... FITC-labeled RGD in the RGD- PEG-PAMAM ...or RGD-PEG-PAMAM treatment may enable cells to produce less ...of RGD-PEG-PAMAM for 6 hours as well as the 293A cells exposed to 250 μ g/mL ...
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