Rhesus Macaques
Inhalational Botulism in Rhesus Macaques Exposed to Botulinum Neurotoxin Complex Serotypes A1 and B1
... Mild splenic lymphoid hyperplasia characterized by de- creased germinal centers was also noted in a number of study monkeys of both sexes and exposed to both serotypes/subtypes and was interpreted to be stress related ...
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Rapid Clearance of Simian Immunodeficiency Virus Particles from Plasma of Rhesus Macaques
... Perturbation of the equilibrium between human immunodeficiency virus type 1 (HIV-1) and the infected host by administering antiretroviral agents has revealed the rapid turnover of both viral particles and productively ...
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Immune correlates of aging in outdoor-housed captive rhesus macaques (Macaca mulatta)
... in rhesus macaques for developing a model of immune ...of macaques exhibited increasing levels of several pro-inflammatory cytokines with age, including IFNγ, IL1β, IL6, IL12, IL15, MIF, sCD40L, and ...
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Altered gene expression in asymptomatic SHIV infected rhesus macaques (Macacca mulatta)
... Simian immunodeficiency virus (SIV), previously referred to as simian T-cell lymphotropic virus type III (STLV-III), induces an AIDS-like disease in its natural host, rhesus macaques. HIV and SIV, members ...
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Viral and immunological factors associated with breast milk transmission of SIV in rhesus macaques
... female rhesus macaques (Macaca mulatta) were selected for the study 15–54 days after vaginal delivery of normal ...on rhesus pri- mary peripheral blood mononuclear cells (PBMC) ...
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Oxidative stress as an indicator of the costs of reproduction among free ranging rhesus macaques
... in rhesus macaques, a moderately polygynous species, sex differences in the costs of reproduction are reflected in the pattern of 8-OHdG concentration, a marker of DNA oxidative ...
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The Affiliative Social Relations Of Free-Ranging Rhesus Macaques In The Context Of Instability
... Across primates, socially integrated individuals exhibit improved genetic fitness compared to their peripheral conspecifics. However, the mechanisms through which this disparity operates is unclear. One hypothesis is ...
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Morphological and immunohistochemical characterization of spontaneous endometriosis in rhesus macaques ( Macaca mulatta
... transfers (Coe et al., 1998; Dick et al., 2003). Since all exam- ined animals, except one, did not have a history of surgical intervention, this had not been a crucial factor for the de- velopment of the disease in the ...
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LFA 1–specific therapy prolongs allograft survival in rhesus macaques
... Five groups of diabetic rhesus macaques received different immunosup- pressive regimens (Table 1). Group 1 received TS-1/22 i.v. on PODs 0 and 3 at 20 mg/kg; on PODs 7, 10, and 14 at 10 mg/kg; and on PODs ...
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The use of preferred social stimuli as rewards for rhesus macaques in behavioural neuroscience
... to macaques, the ques- tion remains as to whether they are sufficiently motivating to function as a reward for adequate task ...male rhesus macaques chose between a smaller fluid reward coupled with ...
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Vaginal transmission of chimeric simian/human immunodeficiency viruses in rhesus macaques.
... Virus isolation. Virus was isolated from heparinized whole blood obtained from the SHIV-inoculated rhesus macaques. PBMC were isolated by Ficoll gradient separation (in Lymphocyte Separation Medium; Organon ...
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Aikeqing decreases viral loads in SHIV89.6-infected Chinese rhesus macaques
... colony-bred rhesus macaques (Macaca mulatta) of Chinese origin that were maintained in accordance with the regula- tions of the American Association for Assessment and Accreditation of Laboratory Animal ...
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Infection, Viral Dissemination, and Antibody Responses of Rhesus Macaques Exposed to the Human Gammaretrovirus XMRV
... control rhesus macaques also exhibited such findings with- out other evidence of prostate infection, arguing against a viral specificity for these observations ...
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Acquisition of Helicobacter pylori Infection in Rhesus Macaques Is Most Consistent with Oral Oral Transmission
... SPF monkeys placed in cages formerly occupied by infected monkeys could potentially have had physical contact with an infected monkey in an adjacent cage. We therefore next per- formed a similar experiment with 4 SPF ...
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Identification of EnteropathogenicEscherichia coli in Simian Immunodeficiency Virus Infected Infant and Adult Rhesus Macaques
... EPEC infection was more frequent in neonatal and infant rhesus macaques. In humans a striking age susceptibility is recognized, with clinical disease seen primarily in infants under 2 years of age (24). ...
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Expression of DC-SIGN by Dendritic Cells of Intestinal and Genital Mucosae in Humans and Rhesus Macaques
... as rhesus ma- caques, provided that rhesus DC-SIGN functions like human DC-SIGN and is expressed in a manner similar to that of its human ...that rhesus ma- caque DC-SIGN efficiently binds and ...
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Epstein-Barr Virus gp350 Can Functionally Replace the Rhesus Lymphocryptovirus Major Membrane Glycoprotein and Does Not Restrict Infection of Rhesus Macaques
... Rhesus macaques provide an animal model in which impor- tant aspects of EBV biology and vaccine development can be strin- gently ...However, macaques cannot be infected with EBV, so the model uses ...
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Immune Activation and Regulation in Simian Immunodeficiency Virus-Plasmodium fragile-Coinfected Rhesus Macaques
... a rhesus macaque model of simian immuno- deficiency virus (SIV)-Plasmodium fragile coinfection to study ...fragile-coinfected rhesus macaques experienced increased viremia and gametocytemia dur- ing ...
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Temporal Characterization of Marburg Virus Angola Infection following Aerosol Challenge in Rhesus Macaques
... Animals. Research was conducted under an IACUC approved protocol in compliance with the Animal Welfare Act, PHS Policy, and other federal statutes and regulations relating to animals and experiments involving animals. ...
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Attenuation of Simian Varicella Virus Infection by Enhanced Green Fluorescent Protein in Rhesus Macaques
... IMPORTANCE SVV infection in nonhuman primates has served as an extremely use- ful animal model to study varicella-zoster virus (VZV) pathogenesis. eGFP-tagged vi- ruses are a great tool to investigate their pathogenesis. ...
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