RNA HELICASE
RNA-Stimulated ATPase and RNA Helicase Activities and RNA Binding Domain of Hepatitis G Virus Nonstructural Protein 3
... an RNA-stimulated ATPase activ- ity nor an RNA helicase activity (data not ...the RNA-stimulated ATPase and RNA helicase activities of HGV NS3 were not derived from contaminating ...
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Vaccinia virus RNA helicase: nucleic acid specificity in duplex unwinding.
... essential RNA helicase that cat- alyzes unidirectional unwinding of 3 9 -tailed duplex RNAs (12, ...virus helicase, known originally as nucleoside triphosphate (NTP) phosphohydrolase-II, or NPH-II ...
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Structurally Conserved Amino Acid W501 Is Required for RNA Helicase Activity but Is Not Essential for DNA Helicase Activity of Hepatitis C Virus NS3 Protein
... the RNA substrate, all three V432 mutants showed strand displacement activities similar to that of the wild-type enzyme in the DNA ...for RNA helicase activity but is not essential for the DNA ...
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Targeting RNA helicase DDX3 in stem cell maintenance and teratoma formation
... DDX3 is an RNA helicase that has antiapoptotic properties, and promotes proliferation and transformation. Besides the role of DDX3 in transformed cells, there is evidence to indicate that DDX3 expression is ...
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Germ Cell Lineage Homeostasis in Drosophila Requires the Vasa RNA Helicase
... Vas RNA helicase early in oogenesis is essential to prevent activation of Chk2 signaling and license the germline component of the Drosophila ovary for further ...
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Conserved requirement for DEAD box RNA helicase Gemin3 in Drosophila oogenesis
... DEAD-box RNA helicase Gemin3 (also referred to as DP130 or DDX20) is a core member of the SMN (survival of motor neurons) complex ...DEAD-box RNA helicases or unwindases are capable of rearranging ...
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In Vitro and In Vivo Analysis of the Interaction between RNA Helicase A and HIV-1 RNA
... (7). RNA helicase A (RHA), also known as DHX9, is an SF2 DExH box protein that can unwind both double- stranded RNA (dsRNA) and double-stranded DNA (dsDNA) by utilizing any of the four ribo- or ...
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Mutational analysis of the hepatitis C virus RNA helicase.
... the RNA binding activity was reduced about twofold, and the RNA helicase activity was almost abol- ...this RNA helicase ...the RNA helicase activity was also ...for ...
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Genetic Requirement For The Rna Helicase Mov10l1 In Pirna Biogenesis
... MOV10L1 RNA helicase activity in piRNA biogenesis in vivo, we generated two knock-in mouse models containing mutations in residues of Mov10l1 that are critical for its RNA helicase ...MOV10L1 ...
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Human Norovirus NS3 Has RNA Helicase and Chaperoning Activities
... ABSTRACT RNA-remodeling proteins, including RNA helicases and chaperones, act to remodel RNA structures and/or protein-RNA interactions and are required for all processes involving ...encode ...
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Pestivirus NS3 (p80) protein possesses RNA helicase activity.
... of RNA helicase activity associated with purified recombinant pestivirus NS3 ...specific RNA-stimulated NTPase activity, whereas preparations derived from NS3-deficient lysates did not; that the NS3 ...
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DDX5/p68 RNA helicase expression is essential for initiating adipogenesis
... Here we demonstrate that DDX5/p68 RNA helicase peaks in expression on day 2 of adipogenesis in two different murine cell lines (Fig. 1a–d). These observations led us to speculate that this transient ...
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The RNA helicase A in malignant transformation
... (RNA helicase A and RHII/Gu), one serine/threonine protein kinase (SRPK1), one HMG protein (SSRP1), and two pre-mRNA splicing factors (PRP8 and hnRNP C) ...
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RNA Helicase A Is an Important Host Factor Involved in Dengue Virus Replication
... viral RNA replica- tion, and the subunits of OST specifically associate with viral NS2B and NS3 proteins using the CRISPR/Cas9 technique (11, ...Through RNA affinity chromatography or quantitative thiouridine ...
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The QRxGRxGRxxxG motif of the vaccinia virus DExH box RNA helicase NPH-II is required for ATP hydrolysis and RNA unwinding but not for RNA binding.
... DNA helicase (27), the potyvirus C1 RNA helicase (12), and the bovine viral diarrhea virus NS3 RNA helicase ...box RNA helicase eIF-4A (see ...the helicase, ...
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The Cellular RNA Helicase UAP56 Is Required for Prevention of Double-Stranded RNA Formation during Influenza A Virus Infection
... exhibit RNA helicase (un- winding) activity (35, ...positive-strand RNA viruses, negative-strand RNA viruses do not appear to produce detectable amounts of viral dsRNA intermediates in ...
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DDX3 DEAD-Box RNA Helicase Is Required for Hepatitis C Virus RNA Replication
... vector-mediated RNA interference to stably knock down DDX3 in three HuH-7-derived cell lines: O cells, harboring a replicative genome-length HCV RNA (HCV-O, genotype 1b) (13); sO cells, harboring its sub- ...
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RNA- and Virus-Independent Inhibition of Antiviral Signaling by RNA Helicase LGP2
... CARD- helicase receptor and IPS-1 ...that RNA sequestration functions in parallel with protein interaction-based inhibition, but it is important to note that the RIG-IC-terminal fragment (RIG-IC) fails to ...
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Involvement of a Toxoplasma DEAD-box RNA Helicase in Post-transcriptional Gene Regulation
... for RNA-mediated gene silencing (RNAi), resulting in the formation of 21-23 nucleotide RNA species that are used in the targeting of the RNAi-induced silencing complex ...
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The RNA Helicase eIF4A Is Required for Sapovirus Translation
... PSaV RNA genome predicted by Mfold ...secondary RNA structures of Sapovirus genogroups I, II, IV, and V (Dresden, AY694184; Mc10, AY237420; Ehime 1107, DQ058829; and NK, AY646856) in schematic ...
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