RNA-induced silencing complex
A Structured Viroid RNA Serves as a Substrate for Dicer-Like Cleavage To Produce Biologically Active Small RNAs but Is Resistant to RNA-Induced Silencing Complex-Mediated Degradation
... RNA silencing is a potent means of antiviral defense in plants and ...of RNA silencing, and some viral RNAs function directly as silencing suppressors as ...trigger RNA ...
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Adenovirus Virus-Associated RNAII-Derived Small RNAs Are Efficiently Incorporated into the RNA-Induced Silencing Complex and Associate with Polyribosomes
... small RNA cDNA library could hypothetically also result from a cloning artifact, where the VA RNAII small RNA population might be ...small RNA pop- ulation ...
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RNAi as an emerging approach to control Fusarium Head Blight disease and mycotoxin contamination in cereals
... gene silencing (HIGS) and spray-induced gene silencing ...hairpin RNA structure into plant ...a RNA-induced silencing complex ...
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Transcriptional Repression and RNA Silencing Act Synergistically To Demonstrate the Function of the Eleventh Component of the Vaccinia Virus Entry-Fusion Complex
... the RNA-induced silencing complex had additional time to form and was distributed throughout the cytoplasm before establishment of specialized DNA factories where VACV transcription occurs ...
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RNA Interference: An Evolutionary Pathway in Periodontal Tissue Engineering
... large complex proteins to form RNA induced silencing complex, commonly called RISC; in association with si ...short RNA. In certain systems, in particu- lar plants, worms and ...
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MicroRNAs associated with therapy of non-small cell lung cancer
... micro- RNA; RISC: RNA induced silencing complex; EGFR-TK: epidermal growth factor receptor-tyrosine kinase; PI3K: phosphoinositide-3 kinase; Akt: protein kinase-B; mTOR: mammalian ...
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Exosomes in Mesenchymal Stem Cells, a New Therapeutic Strategy for Cardiovascular Diseases?
... RISC: RNA-induced silencing complex; VEGF: Vascular endothelial growth factor; SMCs: Smooth muscle cells; CHF: Congestive heart failure; Mecp2: Methyl CpG binding protein 2; PUMA: p53 ...
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RNAi therapy to the wall of arteries and veins: anatomical, physiologic, and pharmacological considerations
... non-coding RNA molecules (~22 bp) that contain an imperfectly base-paired hairpin segment ...the RNA- induced silencing complex ...this complex directs the miRNA to the target ...
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RNA silencing and HIV: A hypothesis for the etiology of the severe combined immunodeficiency induced by the virus
... antisense RNA with multiple functions (Figure 3a– d)[14]. The HIVaINR antisense RNA encodes a set of pro- teins called HIV antisense proteins (HAPs) ...antisense RNA enables intrinsic viral ...
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RNA silencing in Monterey
... by RNA polymerase II, resulting in the production of a primary miRNA ...‘microprocessor complex’ (composed of the RNase III enzyme Drosha and its co-factor Dgcr8) and is cleaved (yellows arrows) by Drosha ...
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RNA Silencing in Aspergillus nidulans Is Independent of RNA-Dependent RNA Polymerases
... NA silencing refers to a group of very similar post- ases (RDRPs) are essential components of RNA silenc- transcriptional gene-silencing mechanisms that ing ...of RNA silencing are ...
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Spliced leader RNA silencing (SLS) a programmed cell death pathway in Trypanosoma brucei that is induced upon ER stress
... whose silencing abolished the SLS ...SL RNA transcription and to accumulate tSNAP42 (manuscript in ...SL RNA transcription complex during SLS. Purifi- cation of the SL RNA transcription ...
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Targeting of Dicer-2 and RNA by a Viral RNA Silencing Suppressor in Drosophila Cells
... antiserum-captured complex or im- munoprecipitates from control cells ...inhibits RNA silencing of GFP induced by dsRNA in Drosophila S2 ...the RNA-binding domain (RBD) is composed of ...
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The miRNA Biogenesis Machinery Modulates Lineage Commitment During αβ T Cell Development
... gene silencing at sites of constitutive heterochromatin such as centromeric ...an RNA-‐dependent RNA polymerase complex (RDRC)) results in the generation of dsRNAs that are processed to ...
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RNA induced epigenetic silencing inhibits HIV 1 reactivation from latency
... of RNA Pol II is associated with genes susceptible to rapid reactiva- ...ated RNA Pol II at the LTR ...of RNA Pol II pSer2 compared to ...of RNA Pol II has been described in highly transcribed ...
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Involvement of RDR6 in short range intercellular RNA silencing in Nicotiana benthamiana
... of silencing foci under epi- fluorescent and confocal microscopes, no individual epidermal cells with viral transient GFP fluorescence in the centre of silencing foci were ever found, although ...
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Herpes Simplex Virus Type 1 Suppresses RNA-Induced Gene Silencing in Mammalian Cells
... between silencing and silencing ...suppress RNA silencing in mammalian cells, identify a novel mechanism by which this highly evolved and complex virus is capable of refining the ...
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RNA Interference (RNAi) Induced Gene Silencing: A Promising Approach of Hi-Tech Plant Breeding
... strand RNA (dsRNA) averts the specific gene expres- sion by inducing degeneration in the chain sequence of particular target messenger RNA in the ...of complex molecular techniques be- cause of ...
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Complex Formation of RNA Silencing Proteins in the Perinuclear Region of Neurospora crassa
... meiotic silencing by unpaired DNA (MSUD) targets genes not paired with a homologous partner during meiosis (Shiu et ...aberrant RNA (aRNA; ab- normal RNA that would enter the silencing ...
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RNA protects a nucleoprotein complex against radiation damage
... With the wide use of high-flux third-generation synchrotron sources, radiation damage (RD) has once again become a dominant reason for the failure of structure determination using macromolecular crystallography (MX) in ...
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