ROS Generation
Glucose initially inhibits and later stimulates blood ROS generation
... the generation of NADPH, the cofactor of the oxidative burst enzyme NADPH-oxidase of blood ...the generation of reactive oxygen species (ROS). The new blood ROS ge- neration assay (BRGA) ...
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Cigarette Smoking and Erectile Dysfunction: Focus on NO Bioavailability and ROS Generation
... Main Outcome Measures. There are strong parallels between smoking and ED and considerable evidence support- ing the concept that smoking-related ED is associated with reduced bioavailability of NO because of increased ...
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Possible involvement of ROS generation in vorinostat pretreatment induced enhancement of the antibacterial activity of ciprofloxacin
... Notes: (A) Mean fluorescence intensity (MFI) was shown as the ratio of geometric mean fluorescence intensity of the test sample and the corresponding control. Data shown are representative of three individual ...
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Urea induced ROS generation causes insulin resistance in mice with chronic renal failure
... Urea-induced decrease in insulin-stimulated glucose transport is mediated by mitochondrial ROS. Cells were infected with adenoviral vectors expressing catalase, UCP1, or MnSOD. After 48 hours incubation with urea, ...
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Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes
... induces ROS generation that contributes to the induction of DNA damage or ...is ROS, which is pro- duced by NADPH oxidase upon nSP70 ...and ROS generation, we measured the produc- tion ...
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Airway smooth muscle NOX4 is upregulated and modulates ROS generation in COPD
... of ROS generation were not different be- tween ASM from healthy control, asthmatic and COPD ...of ROS generated following stimulation with hydrogen peroxide using the DCFDA assay was similar in ASM ...
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Petry, Andreas (2009): Characterization of novel NADPH oxidases in endothelial cells under basal and stress conditions. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... been recently found to be expressed in certain types of endothelial cells suggesting that it may play a role in endothelial ROS generation [40]. Interestingly, high levels of NOX2 mRNA have been found in ...
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Antimicrobial use of reactive oxygen therapy: current insights
... of ROS production and the common procedures that exert their antimicrobial effects due to ROS formation are ...reviewed. ROS generation is the antimicrobial mechanism of nanoparticles, ...
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Assessment of complementary feeding of Canadian infants: effects on microbiome & oxidative stress, a randomized controlled trial
... (ROS) generation, gut microbiota and ...fecal ROS formation ( p < ...with ROS and Staphylococcaceae were negatively correlated with ...
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Pyrrolidine Dithiocarbamate Reduces Coxsackievirus B3 Replication through Inhibition of the Ubiquitin-Proteasome Pathway
... massive generation of reactive oxygen species ...alleviated ROS generation, the antiviral activity was unlikely dependent on its antioxidant effect because the potent antioxidant, N-acetyl- L ...
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Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen
... the CO (pre-HBO) group and the control group. This is consistent as CI and CIII are considered the major sites for ROS production whereas CIV is generally not a source of ROS production as seen with our ...
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Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy
... intracellular ROS, and induced apoptosis in ...radiation-induced ROS and sensitized PCSCs to fractionated ...enhanced ROS generation, promoted radiation sensitivity, and attenuated tumor ...
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Differential activation of RAW 264.7 macrophages by size-segregated crystalline silica
... cellular ROS generation results from the CS interaction with the plasma mem- brane prior to phagocytosis, as a result of lipid peroxida- ...mROS generation occurring with the introduction of the CS ...
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Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling
... induced ROS generation and caused redox imbalance, oxidative stress, and NO/NOS system disorder, leading to oxidative damage and inflammation response, which conse- quently resulted in endothelial ...
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Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidative stress and endoplasmic reticulum stress
... processes has been identified, so we reasoned that iNOS inhibition may recover progranulin-induced ER stress response and increased autophagy, preventing from insulin resistance in adipocytes. As expected, 30 μM ...
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Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and reactive oxygen species generation in A549 and NCI H1299 non small cell lung cancer cells
... of ROS products that induce cell death in various cancer cell types [12, ...through ROS [39] and that the generation of ROS products is prevented by ROS scavengers, which results in the ...
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Theory of pleiotropic action of biologically active compounds and medicines—Basic principles and practical application
... sociated ROS generation it became possible to establish the ...Nox2-dependent ROS generation, the com- bination should form a SAP-pattern, and in case of dose- dependent antagonistic ...
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Threshold effect in the H2O2 production of skeletal muscle mitochondria during fasting and refeeding
... affects ROS generation in these two metabolically contrasted skeletal muscles and whether mitochondrial adjustments to fasting drive a change in % ROS/ATP remain ...(% ROS/O) and the oxidative ...
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Influence of thiol stress on oxidative phosphorylation and generation of ROS in Streptomyces coelicolor
... Bacteria are versatile and can adapt to extremes of adverse conditions. They, therefore, contain regulatory mechanisms to overcome reductive stress. CatalaseA is found to be induced to a very high level in the presence ...
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A critical role of the transient receptor potential melastatin 2 channel in a positive feedback mechanism for reactive oxygen species‐induced delayed cell death
... induced mitochondrial fragmentation and ROS generation were prevented by treatment with TPEN (Fig. 3f and Fig. 4), suggesting that mitochondrial Zn 2+ accumulation triggers alterations in the mitochondrial ...
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