Rotenone-Induced
Capsicum Protects Against Rotenone-Induced Toxicity in Mice Brain Via Reduced Oxidative Stress and 5-Lipoxygenase Activation
... radicals. Rotenone has been shown to increase the release of reactive oxygen species in vitro [45], increase lipid peroxidation products and to decrease GSH and catalase activity in rodent brain [33, 34, ...the ...
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Effect of Cymbopogon Flexuosus (Lemongrass Oil) against Rotenone-Induced Parkinsonism in Rats
... on rotenone induced rat model of Parkinson‘s disease: Suppression of neuroinflammation and oxidative stress mediated ...ROT induced group and prevented the neuroinflammation in substantia nigra pars ...
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Aging-related rotenone-induced neurochemical and behavioral deficits: role of SIRT2 and redox imbalance, and neuroprotection by AK-7
... aging-related rotenone-induced increase in SIRT2 expression in the SN of ...aging-related rotenone-induced behavior abnormality and striatal DA depletion, and the potential neuroprotec- tion ...
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The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson’s disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain
... from rotenone-induced toxicity in rat primary mixed cell cultures and characterisation of a liposomal formulation of ...of rotenone after 48 h ...h rotenone insult, conferred dose-dependent ...
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PROTECTIVE EFFECTS OF PIPER BETEL PHENOL, HYDROXYCHAVICOL AND ITS DERIVATIVES AGAINST ROTENONE INDUCED NEUROTOXICITY: SYNTHESIS, IN VITRO AND IN VIVO EFFICACY STUDIES
... against rotenone induced toxicity by prevention of oxidative stress and neuro ...in rotenone induced neurotoxicity in ...against rotenone induced alterations in grip strength and ...
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Neuroprotective and Therapeutic Role of Omega-3 Against Oxidative Stress and Neurotransmitter Disturbances in Rotenone-Induced Mice Model of Parkinson's Disease
... The present findings indicate that rotenone induced a significant decrease in cerebral AchE activity. According to the DA-Ach balance hypothesis, DA could inhibit acetylcholine releasein the striatum [48]. ...
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Centella Asiatica Increased the Body Length Through the Modulation of Antioxidant in Rotenone-Induced Zebrafish Larvae
... Centella asiatica (CA) is herbal medicine that used as traditional medicine including ayurvedic theraphy since hundreds years ago. This herb containa of pentacyclic triterpenoids such as asiaticoside, madecassoside, ...
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IN-VIVO ANTIOXIDANT POTENTIALS OF CITRULLUS COLOCYNTHIS SCHARD IN ROTENONE INDUCED PARKINSON’S DISEASE ANIMAL MODEL.
... inhibitor rotenone reproduces features of Parkinson’s disease, including selective nigrostriatal dopaminergic degeneration and α-synuclein- positive cytoplasmic inclusions 8 ...the ROTENONE induced ...
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Curcumin protects against rotenone induced neurotoxicity in cell and drosophila models of Parkinson’s disease
... used rotenone (a mitochondrial complex I inhibitor) based cell and Drosophila models that resemble some key pathological features of PD to test whether curcumin, a po- tent antioxidant compound, derived from the ...
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Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism
... against rotenone-induced ...that rotenone triggering signifi- cant phosphorylation and activation of ERK1/2 was antagonized by baicalein pretreatment, indicating that inactivation of ERK1/2 pathway ...
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In vitro neuroprotective potential of four medicinal plants against rotenone induced toxicity in SH SY5Y neuroblastoma cells
... on rotenone-induced cytotoxicity Cytotoxicity was determined using the sulforhodamine B assay (SRB) as described by Vichai and Kirtikara ...or rotenone alone, a volume of 20 μL of either plant ...
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The effect of Centella asiatica to the vascular endothelial growth factor and vascular endothelial growth factor receptor-2 on the rotenone induced zebrafish larvae (Danio rerio) stunting model
... This research used 2 hpf (hour post fertilization) zebrafish embryos from adult zebrafish fertilization, which has been identified on Hydrology Laboratory in Faculty of Fisheries and Marine Science of Universitas ...
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Piperine induces autophagy by enhancing protein phosphotase 2A activity in a rotenone-induced Parkinson’s disease model
... on rotenone-induced neurotoxicity in SK-N-SH cells, primary rat cortical neurons, and in a mouse ...administered rotenone (10mg/kg) for 6 weeks; PIP (25mg/kg, 50mg/kg) was subsequently administered ...
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Evaluation of Haematological Alterations in Intraperitoneal and Oral Rotenone Induced Parkinson’s Disease Wistar Rat
... inperitoneal rotenone toxicity induced alterations in Hb, RBCs, WBCs and Platelets in ...rot-50-po induced hematological ...oral rotenone (rot- 6-ip and rot-100-po) revealed drastic and abrupt ...
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BEHAVIORAL STUDIES OF DASATINIB AND RESVERATROL IN ROTENONE INDUCED PARKINSON’S RAT MODEL
... in Rotenone Induced PD Rat Model: The effect of different treatments in rotenone-induced PD animals when tested with radial arm maze for evaluating the time taken for task completion is shown ...
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Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH SY 5Y Neuroblastoma cells
... Rotenone, DMC, thiobarbituric acid (TBA), MTT, 2–7- diacetyldichlorofluorescein (DCFH-DA), rhodamine 123 (Rh-123), heat-inactivated fetal calf serum (FCS), Dulbecco’s modified Eagle’s medium (DMEM), glutamine, ...
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Hormetic effect of rotenone in primary human fibroblasts
... in rotenone treated cells but significantly up-regulated with age in replicative senescent MRC-5 fibroblasts ...mild rotenone stress but significantly down-regulated in aging HFF, however not in MRC-5 ...
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Mutants of Chlamydomonas reinhardtii Deficient in Mitochondrial Complex I: Characterization of Two Mutations Affecting the nd1 Coding Sequence
... to rotenone was also ...of rotenone induced a reduction of 56 and 50% oxidase (complex IV) activity; dum20, which lacks rote- of the cell respiration of wild-type and dum19 cells, re- none-sensitive ...
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Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production
... inhibition induced by metformin ...of rotenone-induced CI-dysfunction and metformin-induced mitochondrial dysfunction like those by Karlsson et ...
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The Effect of Rotenone on Ndfip1 in MES23.5 Cells
... with rotenone in a rotenone-induced PD cell ...after rotenone treatment in ...of rotenone on MES ...on rotenone-induced neurotoxicity should be further studied in the ...
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