RTA/1
Induction of Epstein-Barr Virus Latent Membrane Protein 1 by a Lytic Transactivator Rta
... Instead of the truncated LMP1, we focused this study on the regulation of full-length LMP1 in the EBV lytic cycle. Notably, a significant increase of full-length LMP1 has been observed frequently when EBV reactivation is ...
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Renal potassium wasting in renal tubular acidosis (RTA): Its occurrence in types 1 and 2 RTA despite sustained correction of systemic acidosis
... classic RTA, neither renal potassium wasting nor hyperaldosteronism could be explained as a consequence of a gradient restriction on renal H + - Na + exchange because the urinary pH remained greater than, or ...
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K-bZIP of Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 (KSHV/HHV-8) Binds KSHV/HHV-8 Rta and Represses Rta-Mediated Transactivation
... (lanes 1 to 4) or absence (lane 5) of the Rta expression plasmid, CMV- Rta (1 g), together with 0, ...0.5, 1 and 2 g of pCMV-HA-K-bZIP (lanes 1-4, respectively) using ...
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Exploring the DNA Binding Interactions of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Switch Protein by Selective Amplification of Bound Sequences In Vitro
... by RTA expression. EMSA experiments confirm that RTA indeed binds to at least two sequences genetically linked to RTA responsiveness (site A in GBS2 and site D in GBS3), though the affinity of these ...
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The Cellular Peptidyl-Prolyl cis/trans Isomerase Pin1 Regulates Reactivation of Kaposi's Sarcoma-Associated Herpesvirus from Latency
... with Rta and other immediate early (IE) protein expression, followed by Rta-mediated transactivation of delayed early (DE) genes, such as Mta, and which include tumor seeding DE oncoproteins and viral DNA ...
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Activation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) by Inhibitors of Class III Histone Deacetylases: Identification of Sirtuin 1 as a Regulator of the KSHV Life Cycle
... repression. RTA, as a transacti- vator of KSHV lytic genes and lytic replication, plays a central role in the switch of KSHV from latency to lytic ...of RTA is highly controlled in order for the virus to ...
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Quantitative Analysis of the Bidirectional Viral G-Protein-Coupled Receptor and Lytic Latency-Associated Nuclear Antigen Promoter of Kaposi's Sarcoma-Associated Herpesvirus
... Plasmids. All plasmids were sequence verified and match nucleotide po- sitions 127583 to 128879 of the BC-1 KSHV genome (70). Site-directed mutations are shown in Fig. 1B. LANApi and K14p single reporter con- ...
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Kaposi's Sarcoma-Associated Herpesvirus RTA Promotes Degradation of the Hey1 Repressor Protein through the Ubiquitin Proteasome Pathway
... an RTA-specific IgG. Results demonstrated a modest increase in RTA levels in the presence of Hey1-specific siRNAs upon reactivation ...enhance RTA levels during early stages of lytic ...
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Prospective study on Outcome of Antero Posterior Compression Type of Pelvic Injuries treated with Anterior Plating and Posterior Percutaneous Ilio-Sacral Screw Fixation
... s .no Name Ag e/s ex Date of admission 1 Madhiyalag an 43/ M 25.01.2017 35/ M 06.01.2017 2 Gunasekar an Mode of injury RTA RTA Diagnosis Pubicdiastasis with Lt SI joint disruption Pubic [r] ...
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Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 RTA Reactivates Murine Gammaherpesvirus 68 from Latency
... To determine whether H/RTA was able to drive viral repli- cation of MHV-68 to completion, infectious virions in super- natants from S11E transfections were quantitated by plaque assay as previously described (37). ...
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Induction of Protective Immunity against Murine Gammaherpesvirus 68 Infection in the Absence of Viral Latency
... FLAG-tagged RTA expression cassette driven by a -actin CMV immediate-early hybrid pro- moter/enhancer was inserted into the StuI-SpeI-SnaBI sites of pSVL/LAL with either a right or a left ...
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Cellular Corepressor TLE2 Inhibits Replication-and-Transcription- Activator-Mediated Transactivation and Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus
... of RTA to auto-activate its own ...with RTA in a dose-dependent ...by RTA through binding to RRE directly (PAN) or in combination with cellular factors, such as RBP-J (ORF59), is reduced gradually ...
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Comparison of signalling mechanisms underlying UTP-evoked vasoconstriction of rat pulmonary and tail arteries
... The methods used conform to the ARRIVE guidelines and meet the ethical requirements of Strathclyde University (https://www.strath.ac.uk/science/biomedicalresearchatstrathclyde/). Segments of rIPA (Chootip et al., 2002) ...
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Hybrid Brain-Computer Interface: a Novel Method on the Integration of EEG and sEMG Signal for Active Prosthetic Control
... of RTA-2 method, this paper generates a model from Table 2 for the new methodology with the following model feature: (1) high accuracy for detecting movement; (2) suppresses mistake decisions or detection ...
9
Enhanced UV photosensitivity from rapid thermal annealed vertically aligned ZnO nanowires
... the RTA treated at 700°C, 13.6 and 118.4 s for the RTA treated at 800°C, ...after RTA at 700°C and do not change significantly for further ...the RTA-treated NWs under periodic UV illumina- ...
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Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: Dual Role of Replication and Transcription Activator
... how RTA, SSB, and PPF interact with 3F ...with RTA? Similarly, does RTA bind to 3F DNA directly or through interaction with K8? We designed two lines of exper- iment to address these ...on RTA ...
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Rta of Murine Gammaherpesvirus 68 Reactivates the Complete Lytic Cycle from Latency
... the rta homo- logue of gammaherpesviruses. The rta genes of HHV-8, EBV, HVS, and BHV-4 share one common feature: the second exon containing ORF50 is spliced to the first exon by removing an intron carrying ...
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Road Traffic Accident Scenario, Pattern and Forecasting in Bangladesh
... Road traffic accident (RTA) has become one of the major concerns for the de- velopment of a country. A developing country like Bangladesh is not apart from its effects. In spite of great progress in international ...
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Role of MR Urethrography Compared to Conventional Urethrography (Retrograde Urethrography and Opposing Urethrography) in the Surgical Management of Obliterative Urethral Stricture.
... NO 1 2 3 NAME Gopal Saravanan Settu AGE HISTORY 48 RTA with pelvic bone fracture 33 RTA with pelvic bone fracture 20 RTA with pelvic bone fracture RTA with pelvic bone fracture 4 Sampath[r] ...
120
A Virally Encoded Small Peptide Regulates RTA Stability and Facilitates Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication
... Luciferase assays. 293T cells were cotransfected with a luciferase re- porter construct and with the pCR3.1-ORF50 and T3.0 expression vec- tors. The pRL-TK plasmid was also included as an internal control that ...
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