salvianolic acid
Dihydromyricetin and Salvianolic acid B inhibit alpha synuclein aggregation and enhance chaperone mediated autophagy
... [29–31]. Salvianolic acid B (Sal B) is one of the bioactive com- pounds of Salvia miltiorrhiza Bunge extracted from the root of Salvia miltiorrhiza and has been shown to exert various anti-oxidative and ...
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Original Article Salvianolic acid B reduces brain inflammation and oxidative stress after experimental intracerebral hemorrhage
... ICH+Salvianolic acid B (SAB) group (n = ...of Salvianolic acid B ...of Salvianolic acid B administration was based on prior study in rat model of transient middle cerebral artery ...
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Original Article Salvianolic acid B ameliorates hydrogen peroxide-induced barrier disruption in monolayer Caco-2 cells
... Salvianolic acid B (Sal B), a pure bioactive com- pound extracted from Salvia miltiorrhiza, is known for its broad pharmacological potential, including neuro- and cardio-protective proper- ties by ...
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Metabolomic profiles of myocardial ischemia under treatment with salvianolic acid B
... SA-B: salvianolic acid B; VEGF: vascular endothelial growth factor; DMSO: dimethyl sulfoxide; ECG: electrocardiograms; DMEM: Dulbecco ’ s Modified Eagle ’ s Medium; FBS: fetal bovine serum; OD: optical ...
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Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats
... Salvianolic acid B (Sal B), a major bioactive component of the traditional Chinese medical agent, Salvia miltior- rhiza, is widely accepted for use against cardiovascular dis- eases ...
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<p>Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway</p>
... Introduction: Depression is one of the most common neuropsychiatric illnesses which leads to a huge social and economic burden on modern society. So, it is necessary to develop an effective and safe pharmacological ...
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Salvianolic acid B induced upregulation of miR 30a protects cardiac myocytes from ischemia/reperfusion injury
... Salvianolic acid B (Sal B) is the most important and abundant bioactive component of the traditional Chinese herb Salvia miltiorrhiza. Sal B is used widely to treat cardiovascular diseases [21]. Recent data ...
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<p>Salvianolic Acid Alleviated Blood–Brain Barrier Permeability in Spontaneously Hypertensive Rats by Inhibiting Apoptosis in Pericytes via P53 and the Ras/Raf/MEK/ERK Pathway</p>
... Salvianolic acid A (SA) is a water-soluble phenolic acid compound extracted from the dried roots and rhi- zomes of Salvia miltiorrhiza bunge. Studies show signi fi - cant antioxidant, 17 ...
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<p>Salvianolic Acid B-Loaded Chitosan/hydroxyapatite Scaffolds Promotes The Repair Of Segmental Bone Defect By Angiogenesis And Osteogenesis</p>
... a salvianolic acid B-loaded chitosan/ hydroxyapatite (Sal B-CS/HA) bone scaffold with controlled release and effective ...of salvianolic acid B and chitosan/hydroxyapatite (CS/HA) material did ...
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<p>Salvianolic Acid A Exhibits Anti-Inflammatory and Antiarthritic Effects via Inhibiting NF-κB and p38/MAPK Pathways</p>
... In our study, we aim to observe the effect of SAA, a potential anti-in fl ammatory, on in fl ammation in vitro. We focus on investigating the potential effects of SAA on reducing the expression of major in fl ammatory ...
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Salvianolic acid B promotes bone formation by increasing activity of alkaline phosphatase in a rat tibia fracture model: a pilot study
... [12,13]. Salvianolic acid B (Sal B) is a water-soluble active component isolated from Danshen ...phenolic acid and the most active constituent ...
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Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells
... Salvianolic Acid B (Sal B), an active compound extracted from the Chinese herb Salvia miltiorrhiza, is attracting more and more attention due to its biological activities, including antioxidant, ...
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Original Article Salvianolic acid A exhibits anti-tumor activity in nasopharyngeal carcinoma cells through regulation of Pin1
... Salvianolic acid A (SAA, ≥98% purity) powder was purchased from Sigma-Aldrich (Shang- hai). A stock solution of SAA was made at 10 mM in ddH 2 O and stored at -20°C. CN- E2, HNE1, and NP69 cells were ...
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Novel anti infective potential of salvianolic acid B against human serious pathogen Neisseria meningitidis
... Background: Epidemics of meningococcal meningitis cause significant health problems especially in Sub‑Saharan Africa. Novel anti‑infective candidates are needed. In modern anti‑adhesion therapy initial attachment of ...
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Protective efficacy of a single salvianolic acid A treatment on photothrombosis-induced sustained spatial memory impairments
... dementia. Salvianolic acid A (SAA), one of the major active ingredients of Danshen, was demonstrated to be effective in protecting against cerebral ischemic ...Keywords: salvianolic acid A, ...
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Original Article Protective effect of salvianolic acid B on NASH rat liver through restoring intestinal mucosal barrier function
... Abstract: Aim: To investigate the effect of Salvianolic acid B (Sal B) on the disease progress of NASH and change of intestinal barrier function. Methods: Sixty Sprague-Dawley (SD) rats were randomly ...
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Hepatoprotective effect of Matrine salvianolic acid B salt on Carbon Tetrachloride-Induced Hepatic Fibrosis
... adopted salvianolic acid B and Matrine as raw materials to prepare Matrine salvianolic acid B salt, which is first reported in this ...Matrine salvianolic acid B salt has been ...
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Activation of transsulfuration pathway by salvianolic acid a treatment: a homocysteine-lowering approach with beneficial effects on redox homeostasis in high-fat diet-induced hyperlipidemic rats
... [14,15]. Salvianolic acid A (Sal A), an aqueous extract from salvia miltiorrhiza , has been shown to present wide cardioprotective effects in myocardial ischemia, endothelial dysfunction and diabetes with ...
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Salvianolic acid A & B: potential cytotoxic polyphenols in battle against cancer via targeting multiple signaling pathways
... nature, salvianolic acid A & B, which are major bioactive constituents of a traditional Chinses medicinal herb, Salvia ...miltiorrhiza. Salvianolic acid A & B have been reported to owe ...
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Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity
... Salvianolic acid A (Sal A) ， an important component of Radix Salviae Miltiorrhizae (RSM), is effective for the treatment of myocardial infarction (MI) and coronary heart disease due to its potential in the ...
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