salvianolic acid A
Protective efficacy of a single salvianolic acid A treatment on photothrombosis-induced sustained spatial memory impairments
... dementia. Salvianolic acid A (SAA), one of the major active ingredients of Danshen, was demonstrated to be effective in protecting against cerebral ischemic ...Keywords: salvianolic acid A, ...
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Salvianolic acid A & B: potential cytotoxic polyphenols in battle against cancer via targeting multiple signaling pathways
... of salvianolic acids as cardio-protective and antioxidant agents but no one has still attempted to review the anti-cancer properties of salvianolic ...of salvianolic acids with specifically focusing ...
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Activation of transsulfuration pathway by salvianolic acid a treatment: a homocysteine-lowering approach with beneficial effects on redox homeostasis in high-fat diet-induced hyperlipidemic rats
... [14,15]. Salvianolic acid A (Sal A), an aqueous extract from salvia miltiorrhiza , has been shown to present wide cardioprotective effects in myocardial ischemia, endothelial dysfunction and diabetes with ...
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<p>Salvianolic Acid A Exhibits Anti-Inflammatory and Antiarthritic Effects via Inhibiting NF-κB and p38/MAPK Pathways</p>
... In our study, we aim to observe the effect of SAA, a potential anti-in fl ammatory, on in fl ammation in vitro. We focus on investigating the potential effects of SAA on reducing the expression of major in fl ammatory ...
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<p>Salvianolic acid A attenuates CCl<sub>4</sub>-induced liver fibrosis by regulating the PI3K/AKT/mTOR, Bcl-2/Bax and caspase-3/cleaved caspase-3 signaling pathways</p>
... whether salvianolic acid A (SA-A), a traditional Chinese medicine extracted from the plant Danshen, could effectively inhibit the liver fi brosis, which is induced by CCl 4 in ...
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Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity
... Salvianolic acid A (Sal A) ， an important component of Radix Salviae Miltiorrhizae (RSM), is effective for the treatment of myocardial infarction (MI) and coronary heart disease due to its potential in the ...
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Original Article Salvianolic acid A exhibits anti-tumor activity in nasopharyngeal carcinoma cells through regulation of Pin1
... Salvianolic acid A (SAA, ≥98% purity) powder was purchased from Sigma-Aldrich (Shang- hai). A stock solution of SAA was made at 10 mM in ddH 2 O and stored at -20°C. CN- E2, HNE1, and NP69 cells were ...
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Antioxidant activity and components of a traditional chinese medicine formula consisting of Crataegus pinnatifida and Salvia miltiorrhiza
... chlorogenic acid, rutin, and ( − )-epicatechin [5], while the active components of DS have been identified as salvianolic acid A and salvianolic acid B ...
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Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection
... especially salvianolic acid A (Sal A) and salvianolic acid B (Sal B), have been found to have potent anti-oxidative capabilities due to their polyphenolic ...by salvianolic acids in ...
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Effects of Different Proportions of Salvianolic Acid and Hydroxysafflor Yellow A on the Myocardial Ischemia Model Induced by Pituitrin in Rats
... years. Salvianolic acids, especially salvianolic acid A (Sal A) and salvianolic acid B (Sal B), have been found to have potent anti– oxidative capabilities due to their polyphenolic ...
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A computational and functional study elicits the ameliorating effect of the Chinese herbal formula <em>Huo Luo Xiao Ling Dan</em> on experimental ischemia-induced myocardial injury in rats via inhibition of apoptosis
... ferulic acid, ligustilide, succinic acid, vanillic acid, tanshinone IIA, tanshinone IIB, danshensu, salvianolic acid A, salvianolic acid B, salvianolic acid ...
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<p>Salvianolic Acid Alleviated Blood–Brain Barrier Permeability in Spontaneously Hypertensive Rats by Inhibiting Apoptosis in Pericytes via P53 and the Ras/Raf/MEK/ERK Pathway</p>
... Salvianolic acid A (SA) is a water-soluble phenolic acid compound extracted from the dried roots and rhi- zomes of Salvia miltiorrhiza bunge. Studies show signi fi - cant antioxidant, 17 ...
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<p>Salvianolic Acid B-Loaded Chitosan/hydroxyapatite Scaffolds Promotes The Repair Of Segmental Bone Defect By Angiogenesis And Osteogenesis</p>
... MC3T3-E1 cells were purchased from the Cell Bank of the Shanghai Institute of Life Sciences (ATCC CRL-2594, Chinese Academy of Sciences, Shanghai, People ’ s Republic of China) and cultured in DMEM/F12 medium ...
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Original Article Salvianolic acid B ameliorates hydrogen peroxide-induced barrier disruption in monolayer Caco-2 cells
... [40]. Salvianolic acid is one of the bioactive compounds of Salvia ...Among salvianolic acids, Sal A and Sal B are the most abundant ...of salvianolic acids on hepatic protection [41], neural ...
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Original Article Salvianolic acid B protects against spinal cord injuries via microRNA-21/PTEN/AKT pathways in rats
... Recently, salvianolic acid B (Sal B), a compound extracted from Salvia miltiorrhiza, has been demon- strated to hold antioxidant, anti-inflammatory, and antiapoptotic ...
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Original Article Salvianolic acid B attenuates lung ischemia-reperfusion injury in rat possibly by inhibiting the P2X7/NLRP3 signaling pathway
... LIRI. Salvianolic acid B (Sal B) is a natural active product extracted from Salvia miltiorrhiza Bge, and protects cardiac myocytes as well as neurons from ischemia-reperfusion ...
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Salvianolic acid B protects against myocardial damage caused by nanocarrier TiO<sub>2</sub>; and synergistic anti-breast carcinoma effect with curcumin via codelivery system of folic acid-targeted and polyethylene glycol-modified TiO<sub>2</sub> nanoparticles
... Technology Co Ltd (Shanghai, China). TiO 2 NPs were purchased from Aladdin (Shanghai, China). Coumarin 6 was purchased from Thermo Fisher Scientific (Waltham, MA, USA). 1,10-Dioctadecyl-3,3,3,3-tetramethyl ...
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Original Article Protective effect of salvianolic acid B on NASH rat liver through restoring intestinal mucosal barrier function
... Abstract: Aim: To investigate the effect of Salvianolic acid B (Sal B) on the disease progress of NASH and change of intestinal barrier function. Methods: Sixty Sprague-Dawley (SD) rats were randomly ...
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Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome
... These results suggest that autophagy process may inter- act with NLRP3 inflammasome to promote depression- like behaviors and neuroimmune activation, which may also actively participate [r] ...
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Aqueous Extract of Tournefortia sarmentosa Stem Inhibits ADP-induced Platelet Aggregation
... PRP was treated with T. sarmentosa stem extract or each compound (100 μM) for 30 min. Washed platelets were prepared in modified calcium-free Tyrode buffer and then incubated with 10 μM forskolin and 10 μM ADP at 37° for ...
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